| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ACP1 | PDGFRB | Tyr857 | DIMRDSNyISKGSTF | dephosphorylation down-regulates activity | 12149261 | SIGNOR-248452 |
| PDGFRB | PDGFRB | Tyr857 | DIMRDSNyISKGSTF | phosphorylation unknown | 2550144 | SIGNOR-22997 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ACP1 | dephosphorylation down-regulates ⊣ | PDGFRB PTyr857 | dephosphorylation up-regulates → | PDGFRB | 12149261 | SIGNOR-248452 |
| PDGFRB | phosphorylation up-regulates → | PDGFRB PTyr857 | phosphorylation down-regulates ⊣ | PDGFRB | 2550144 | SIGNOR-22997 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ACP1 | dephosphorylation → down-regulates activity | PDGFRB | SIGNOR-248452 |
| PDGFRB | phosphorylation → unknown | PDGFRB | SIGNOR-22997 |
