| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | PDGFRB | Tyr970 | GEGYKKKyQQVDEEF | phosphorylation up-regulates activity | 19275932 | SIGNOR-276143 |
| ABL1 | PDGFRB | Tyr970 | GEGYKKKyQQVDEEF | phosphorylation down-regulates | 19275932 | SIGNOR-184556 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ABL1 | phosphorylation up-regulates → | PDGFRB PTyr970 | phosphorylation up-regulates → | PDGFRB | 19275932 | SIGNOR-276143 |
| ABL1 | phosphorylation up-regulates → | PDGFRB PTyr970 | phosphorylation down-regulates ⊣ | PDGFRB | 19275932 | SIGNOR-184556 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ABL1 | phosphorylation → up-regulates activity | PDGFRB | SIGNOR-276143 |
| ABL1 | phosphorylation![]() down-regulates | PDGFRB | SIGNOR-184556 |