| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | CALM1 | Tyr100 | FDKDGNGyISAAELR | phosphorylation down-regulates | 7925415 | SIGNOR-34691 |
| INSR | CALM1 | Tyr100 | FDKDGNGyISAAELR | phosphorylation down-regulates | 3415247 | SIGNOR-24782 |
| EGFR | CALM1 | Tyr100 | FDKDGNGyISAAELR | phosphorylation down-regulates | 3415247 | SIGNOR-24778 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| EGFR | phosphorylation up-regulates → | CALM1 PTyr100 | phosphorylation down-regulates ⊣ | CALM1 | 7925415 | SIGNOR-34691 |
| INSR | phosphorylation up-regulates → | CALM1 PTyr100 | phosphorylation down-regulates ⊣ | CALM1 | 3415247 | SIGNOR-24782 |
| EGFR | phosphorylation up-regulates → | CALM1 PTyr100 | phosphorylation down-regulates ⊣ | CALM1 | 3415247 | SIGNOR-24778 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| EGFR | phosphorylation down-regulates | CALM1 | SIGNOR-34691 |
| INSR | phosphorylation down-regulates | CALM1 | SIGNOR-24782 |
| EGFR | phosphorylation down-regulates | CALM1 | SIGNOR-24778 |
