| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | RRAS | Tyr66 | DPTIEDSyTKICSVD | phosphorylation down-regulates activity | 11682467 | SIGNOR-111189 |
| EPHB2 | RRAS | Tyr66 | DPTIEDSyTKICSVD | phosphorylation down-regulates activity | 10570155 | SIGNOR-251125 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| SRC | phosphorylation up-regulates → | RRAS PTyr66 | phosphorylation down-regulates ⊣ | RRAS | 11682467 | SIGNOR-111189 |
| EPHB2 | phosphorylation up-regulates → | RRAS PTyr66 | phosphorylation down-regulates ⊣ | RRAS | 10570155 | SIGNOR-251125 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| SRC | phosphorylation → down-regulates activity | RRAS | SIGNOR-111189 |
| EPHB2 | phosphorylation → down-regulates activity | RRAS | SIGNOR-251125 |