| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK8 | BCL2 | Thr69 | SRDPVARtSPLQTPA | phosphorylation down-regulates | 18570871 | SIGNOR-179096 |
| MAPK8 | BCL2 | Thr69 | SRDPVARtSPLQTPA | phosphorylation down-regulates | 10567572 | SIGNOR-72361 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK8 | phosphorylation up-regulates → | BCL2 PThr69 | phosphorylation down-regulates ⊣ | BCL2 | 18570871 | SIGNOR-179096 |
| MAPK8 | phosphorylation up-regulates → | BCL2 PThr69 | phosphorylation down-regulates ⊣ | BCL2 | 10567572 | SIGNOR-72361 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK8 | phosphorylation![]() down-regulates | BCL2 | SIGNOR-179096 |
| MAPK8 | phosphorylation![]() down-regulates | BCL2 | SIGNOR-72361 |