Entity Details

Name CDK1_Thr56
ID P10415
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
CDK1BCL2Thr56FSSQPGHtPHPAASRphosphorylation
up-regulates activity		10766756SIGNOR-76837
MAPK1BCL2Thr56FSSQPGHtPHPAASRphosphorylation
up-regulates quantity by stabilization		10669763SIGNOR-74923
LRRK2BCL2Thr56FSSQPGHtPHPAASRphosphorylation
up-regulates activity		25446991SIGNOR-279531
MAPK14BCL2Thr56FSSQPGHtPHPAASRphosphorylation
down-regulates activity		16714293SIGNOR-146786
MAPK3BCL2Thr56FSSQPGHtPHPAASRphosphorylation
up-regulates quantity by stabilization		10669763SIGNOR-74939
ERK1/2BCL2Thr56FSSQPGHtPHPAASRphosphorylation
up-regulates quantity by stabilization		10669763SIGNOR-244610
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
CDK1phosphorylation
up-regulates
→
BCL2
PThr56		phosphorylation
up-regulates
→		BCL210766756SIGNOR-76837
MAPK1phosphorylation
up-regulates
→
BCL2
PThr56		phosphorylation
up-regulates
→		BCL210669763SIGNOR-74923
LRRK2phosphorylation
up-regulates
→
BCL2
PThr56		phosphorylation
up-regulates
→		BCL225446991SIGNOR-279531
MAPK14phosphorylation
up-regulates
→
BCL2
PThr56		phosphorylation
down-regulates
⊣		BCL216714293SIGNOR-146786
MAPK3phosphorylation
up-regulates
→
BCL2
PThr56		phosphorylation
up-regulates
→		BCL210669763SIGNOR-74939
ERK1/2phosphorylation
up-regulates
→
BCL2
PThr56		phosphorylation
up-regulates
→		BCL210669763SIGNOR-244610
Regulator Mechanism/Effect Target SIGNOR-ID
CDK1phosphorylation
→
up-regulates activity 		BCL2SIGNOR-76837
MAPK1phosphorylation
→
up-regulates quantity by stabilization 		BCL2SIGNOR-74923
LRRK2phosphorylation
→
up-regulates activity 		BCL2SIGNOR-279531
MAPK14phosphorylation
→
down-regulates activity 		BCL2SIGNOR-146786
MAPK3phosphorylation
→
up-regulates quantity by stabilization 		BCL2SIGNOR-74939
ERK1/2phosphorylation
→
up-regulates quantity by stabilization 		BCL2SIGNOR-244610