| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | FGFR1 | Ser777 | SMPLDQYsPSFPDTR | phosphorylation down-regulates | 23405013 | SIGNOR-200884 |
| ERK1/2 | FGFR1 | Ser777 | SMPLDQYsPSFPDTR | phosphorylation down-regulates | 23405013 | SIGNOR-244541 |
| MAPK1 | FGFR1 | Ser777 | SMPLDQYsPSFPDTR | phosphorylation down-regulates | 23405013 | SIGNOR-200880 |
| MAPK14 | FGFR1 | Ser777 | SMPLDQYsPSFPDTR | phosphorylation down-regulates | 20626350 | SIGNOR-166598 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK3 | phosphorylation up-regulates → | FGFR1 PSer777 | phosphorylation down-regulates ⊣ | FGFR1 | 23405013 | SIGNOR-200884 |
| ERK1/2 | phosphorylation up-regulates → | FGFR1 PSer777 | phosphorylation down-regulates ⊣ | FGFR1 | 23405013 | SIGNOR-244541 |
| MAPK1 | phosphorylation up-regulates → | FGFR1 PSer777 | phosphorylation down-regulates ⊣ | FGFR1 | 23405013 | SIGNOR-200880 |
| MAPK14 | phosphorylation up-regulates → | FGFR1 PSer777 | phosphorylation down-regulates ⊣ | FGFR1 | 20626350 | SIGNOR-166598 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK3 | phosphorylation down-regulates | FGFR1 | SIGNOR-200884 |
| ERK1/2 | phosphorylation down-regulates | FGFR1 | SIGNOR-244541 |
| MAPK1 | phosphorylation down-regulates | FGFR1 | SIGNOR-200880 |
| MAPK14 | phosphorylation down-regulates | FGFR1 | SIGNOR-166598 |
