| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | TOP2A | Ser1247 | KNENTEGsPQEDGVE | phosphorylation unknown | 7635160 | SIGNOR-30244 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | phosphorylation up-regulates → | TOP2A PSer1247 | phosphorylation down-regulates ⊣ | TOP2A | 7635160 | SIGNOR-30244 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK1 | phosphorylation → unknown | TOP2A | SIGNOR-30244 |
