| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPM1K | BCKDHA | Ser337 | TYRIGHHsTSDDSSA | dephosphorylation up-regulates activity | 19411760 | SIGNOR-248758 |
| BCKDK | BCKDHA | Ser337 | TYRIGHHsTSDDSSA | phosphorylation down-regulates | 3947057 | SIGNOR-25084 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPM1K | dephosphorylation down-regulates ⊣ | BCKDHA PSer337 | dephosphorylation down-regulates ⊣ | BCKDHA | 19411760 | SIGNOR-248758 |
| BCKDK | phosphorylation up-regulates → | BCKDHA PSer337 | phosphorylation down-regulates ⊣ | BCKDHA | 3947057 | SIGNOR-25084 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PPM1K | dephosphorylation → up-regulates activity | BCKDHA | SIGNOR-248758 |
| BCKDK | phosphorylation down-regulates | BCKDHA | SIGNOR-25084 |
