Entity Details

Name XRCC6
ID P12956
Role substrate
Enzymatic Domains
Ku 261-468
SAP 573-607
PROSITE-ProRule
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PRKDCXRCC6Ser27
View in OncoXplorer
QEENLEAsGDYKYSGphosphorylation
up-regulates activity		26337656SIGNOR-274022
ATMXRCC6Ser27
View in OncoXplorer
QEENLEAsGDYKYSGphosphorylation
up-regulates activity		26337656SIGNOR-274020
PRKDCXRCC6Ser33ASGDYKYsGRDSLIFphosphorylation
up-regulates activity		26337656SIGNOR-274023
ATMXRCC6Ser33ASGDYKYsGRDSLIFphosphorylation
up-regulates activity		26337656SIGNOR-274021
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PRKDCphosphorylation
up-regulates
→
XRCC6
PSer27		phosphorylation
up-regulates
→		XRCC626337656SIGNOR-274022
ATMphosphorylation
up-regulates
→
XRCC6
PSer27		phosphorylation
up-regulates
→		XRCC626337656SIGNOR-274020
PRKDCphosphorylation
up-regulates
→
XRCC6
PSer33		phosphorylation
up-regulates
→		XRCC626337656SIGNOR-274023
ATMphosphorylation
up-regulates
→
XRCC6
PSer33		phosphorylation
up-regulates
→		XRCC626337656SIGNOR-274021
Regulator Mechanism/Effect Target SIGNOR-ID
PRKDCphosphorylation
→
up-regulates activity 		XRCC6SIGNOR-274022
ATMphosphorylation
→
up-regulates activity 		XRCC6SIGNOR-274020
PRKDCphosphorylation
→
up-regulates activity 		XRCC6SIGNOR-274023
ATMphosphorylation
→
up-regulates activity 		XRCC6SIGNOR-274021