Entity Details

Name XRCC6
ID P12956
Role substrate
Enzymatic Domains
Ku 261-468
SAP 573-607
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
ATMXRCC6Ser27
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QEENLEAsGDYKYSGphosphorylation
up-regulates activity		26337656SIGNOR-274020
ATMXRCC6Ser33ASGDYKYsGRDSLIFphosphorylation
up-regulates activity		26337656SIGNOR-274021
PRKDCXRCC6Ser33ASGDYKYsGRDSLIFphosphorylation
up-regulates activity		26337656SIGNOR-274023
PRKDCXRCC6Ser27
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QEENLEAsGDYKYSGphosphorylation
up-regulates activity		26337656SIGNOR-274022
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
ATMphosphorylation
up-regulates
→
XRCC6
PSer27		phosphorylation
up-regulates
→		XRCC626337656SIGNOR-274020
ATMphosphorylation
up-regulates
→
XRCC6
PSer33		phosphorylation
up-regulates
→		XRCC626337656SIGNOR-274021
PRKDCphosphorylation
up-regulates
→
XRCC6
PSer33		phosphorylation
up-regulates
→		XRCC626337656SIGNOR-274023
PRKDCphosphorylation
up-regulates
→
XRCC6
PSer27		phosphorylation
up-regulates
→		XRCC626337656SIGNOR-274022
Regulator Mechanism/Effect Target SIGNOR-ID
ATMphosphorylation
→
up-regulates activity 		XRCC6SIGNOR-274020
ATMphosphorylation
→
up-regulates activity 		XRCC6SIGNOR-274021
PRKDCphosphorylation
→
up-regulates activity 		XRCC6SIGNOR-274023
PRKDCphosphorylation
→
up-regulates activity 		XRCC6SIGNOR-274022