Entity Details

Name AKT_Thr440
ID P15056
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
AKT2BRAFThr440EDRNRMKtLGRRDSSphosphorylation
down-regulates		10869359SIGNOR-78689
AKTBRAFThr440EDRNRMKtLGRRDSSphosphorylation
down-regulates		10869359SIGNOR-244156
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
AKT2phosphorylation
up-regulates
→
BRAF
PThr440		phosphorylation
down-regulates
⊣		BRAF10869359SIGNOR-78689
AKTphosphorylation
up-regulates
→
BRAF
PThr440		phosphorylation
down-regulates
⊣		BRAF10869359SIGNOR-244156
Regulator Mechanism/Effect Target SIGNOR-ID
AKT2phosphorylation
img/direct_inhibition.png
down-regulates 		BRAFSIGNOR-78689
AKTphosphorylation
img/direct_inhibition.png
down-regulates 		BRAFSIGNOR-244156