Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
ERK1/2	BRAF	Thr401 View in OncoXplorer	STTGLSAtPPASLPG	phosphorylation down-regulates	21135229	SIGNOR-170339

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
ERK1/2	phosphorylation up-regulates →	BRAF PThr401	phosphorylation down-regulates ⊣	BRAF	21135229	SIGNOR-170339

Regulator	Mechanism/Effect	Target	SIGNOR-ID
ERK1/2	phosphorylation down-regulates	BRAF	SIGNOR-170339