Entity Details

Name ERK1/2_Ser151
ID P15056
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK3BRAFSer151VARSNPKsPQKPIVRphosphorylation
down-regulates activity		21478863SIGNOR-259921
ERK1/2BRAFSer151VARSNPKsPQKPIVRphosphorylation
down-regulates activity		21478863SIGNOR-259919
MAPK1BRAFSer151VARSNPKsPQKPIVRphosphorylation
down-regulates activity		21478863SIGNOR-259920
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK3phosphorylation
up-regulates
→
BRAF
PSer151		phosphorylation
down-regulates
⊣		BRAF21478863SIGNOR-259921
ERK1/2phosphorylation
up-regulates
→
BRAF
PSer151		phosphorylation
down-regulates
⊣		BRAF21478863SIGNOR-259919
MAPK1phosphorylation
up-regulates
→
BRAF
PSer151		phosphorylation
down-regulates
⊣		BRAF21478863SIGNOR-259920
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK3phosphorylation
→
down-regulates activity 		BRAFSIGNOR-259921
ERK1/2phosphorylation
→
down-regulates activity 		BRAFSIGNOR-259919
MAPK1phosphorylation
→
down-regulates activity 		BRAFSIGNOR-259920