| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| VRK1 | ATF2 | Ser62 | FGPARNDsVIVADQT | phosphorylation up-regulates | 15105425 | SIGNOR-124330 |
| PAK1 | ATF2 | Ser62 | FGPARNDsVIVADQT | phosphorylation down-regulates activity | 28918037 | SIGNOR-279377 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| VRK1 | phosphorylation up-regulates → | ATF2 PSer62 | phosphorylation up-regulates → | ATF2 | 15105425 | SIGNOR-124330 |
| PAK1 | phosphorylation up-regulates → | ATF2 PSer62 | phosphorylation down-regulates ⊣ | ATF2 | 28918037 | SIGNOR-279377 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| VRK1 | phosphorylation → up-regulates | ATF2 | SIGNOR-124330 |
| PAK1 | phosphorylation → down-regulates activity | ATF2 | SIGNOR-279377 |
