Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CSNK1E	TCF3	–		phosphorylation up-regulates	11524435	SIGNOR-110056
MAP3K10	TCF3	Thr355	NFSSSPStPVGSPQG	phosphorylation down-regulates	19801649	SIGNOR-161544
MAP3K10	TCF3	Ser359	SPSTPVGsPQGLAGT	phosphorylation down-regulates	19801649	SIGNOR-161531
MAP3K10	TCF3	Ser352	SSNNFSSsPSTPVGS	phosphorylation down-regulates	19801649	SIGNOR-161527
MAPK3	TCF3	Thr355	NFSSSPStPVGSPQG	phosphorylation down-regulates quantity by destabilization	14592976	SIGNOR-249117
MAP3K10	TCF3	Ser379 View in OncoXplorer	AGAPGALsPSYDGGL	phosphorylation down-regulates	19801649	SIGNOR-161540
MAPK11	TCF3	Ser139 View in OncoXplorer	LNSPGPLsPSGMKGT	phosphorylation up-regulates	15719023	SIGNOR-134190
PAK5	TCF3	Ser39	NGKGRPAsLAGAQFG	phosphorylation up-regulates activity	26212009	SIGNOR-275653
MAPK14	TCF3	Ser139 View in OncoXplorer	LNSPGPLsPSGMKGT	phosphorylation up-regulates activity	15719023	SIGNOR-134194
HIPK2	TCF3	–		phosphorylation down-regulates activity	21285352	SIGNOR-279193
MAP3K10	TCF3	Ser341	KALASIYsPDHSSNN	phosphorylation down-regulates	19801649	SIGNOR-161523
ERK1/2	TCF3	–		phosphorylation down-regulates quantity by destabilization	14592976	SIGNOR-270139
Gbeta	TCF3	–		phosphorylation down-regulates quantity by destabilization	14592976	SIGNOR-270009
MAPK1	TCF3	Thr355	NFSSSPStPVGSPQG	phosphorylation down-regulates quantity by destabilization	14592976	SIGNOR-249451
MAPKAPK2	TCF3	–		phosphorylation up-regulates	20626350	SIGNOR-166643

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAP3K10	phosphorylation up-regulates →	TCF3 PThr355	phosphorylation down-regulates ⊣	TCF3	19801649	SIGNOR-161544
MAP3K10	phosphorylation up-regulates →	TCF3 PSer359	phosphorylation down-regulates ⊣	TCF3	19801649	SIGNOR-161531
MAP3K10	phosphorylation up-regulates →	TCF3 PSer352	phosphorylation down-regulates ⊣	TCF3	19801649	SIGNOR-161527
MAPK3	phosphorylation up-regulates →	TCF3 PThr355	phosphorylation down-regulates ⊣	TCF3	14592976	SIGNOR-249117
MAP3K10	phosphorylation up-regulates →	TCF3 PSer379	phosphorylation down-regulates ⊣	TCF3	19801649	SIGNOR-161540
MAPK11	phosphorylation up-regulates →	TCF3 PSer139	phosphorylation up-regulates →	TCF3	15719023	SIGNOR-134190
PAK5	phosphorylation up-regulates →	TCF3 PSer39	phosphorylation up-regulates →	TCF3	26212009	SIGNOR-275653
MAPK14	phosphorylation up-regulates →	TCF3 PSer139	phosphorylation up-regulates →	TCF3	15719023	SIGNOR-134194
MAP3K10	phosphorylation up-regulates →	TCF3 PSer341	phosphorylation down-regulates ⊣	TCF3	19801649	SIGNOR-161523
MAPK1	phosphorylation up-regulates →	TCF3 PThr355	phosphorylation down-regulates ⊣	TCF3	14592976	SIGNOR-249451

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CSNK1E	phosphorylation → up-regulates	TCF3	SIGNOR-110056
MAP3K10	phosphorylation down-regulates	TCF3	SIGNOR-161544
MAP3K10	phosphorylation down-regulates	TCF3	SIGNOR-161531
MAP3K10	phosphorylation down-regulates	TCF3	SIGNOR-161527
MAPK3	phosphorylation down-regulates quantity by destabilization	TCF3	SIGNOR-249117
MAP3K10	phosphorylation down-regulates	TCF3	SIGNOR-161540
MAPK11	phosphorylation → up-regulates	TCF3	SIGNOR-134190
PAK5	phosphorylation → up-regulates activity	TCF3	SIGNOR-275653
MAPK14	phosphorylation → up-regulates activity	TCF3	SIGNOR-134194
HIPK2	phosphorylation → down-regulates activity	TCF3	SIGNOR-279193
MAP3K10	phosphorylation down-regulates	TCF3	SIGNOR-161523
ERK1/2	phosphorylation down-regulates quantity by destabilization	TCF3	SIGNOR-270139
Gbeta	phosphorylation down-regulates quantity by destabilization	TCF3	SIGNOR-270009
MAPK1	phosphorylation down-regulates quantity by destabilization	TCF3	SIGNOR-249451
MAPKAPK2	phosphorylation → up-regulates	TCF3	SIGNOR-166643