Entity Details

Name H2AX_Tyr143
ID P16104
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
BAZ1BH2AXTyr143ATQASQEyphosphorylation
up-regulates		19092802SIGNOR-182831
EYA1H2AXTyr143ATQASQEydephosphorylation
down-regulates		20965415SIGNOR-168879
EYA3H2AXTyr143ATQASQEydephosphorylation
down-regulates		20965415SIGNOR-168927
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
BAZ1Bphosphorylation
up-regulates
→
H2AX
PTyr143		phosphorylation
up-regulates
→		H2AX19092802SIGNOR-182831
EYA1dephosphorylation
down-regulates
⊣
H2AX
PTyr143		dephosphorylation
up-regulates
→		H2AX20965415SIGNOR-168879
EYA3dephosphorylation
down-regulates
⊣
H2AX
PTyr143		dephosphorylation
up-regulates
→		H2AX20965415SIGNOR-168927
Regulator Mechanism/Effect Target SIGNOR-ID
BAZ1Bphosphorylation
→
up-regulates 		H2AXSIGNOR-182831
EYA1dephosphorylation
img/direct_inhibition.png
down-regulates 		H2AXSIGNOR-168879
EYA3dephosphorylation
img/direct_inhibition.png
down-regulates 		H2AXSIGNOR-168927