| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATR | CREB1 | Ser107 | SVDSVTDsQKRREIL | phosphorylation down-regulates | 15073328 | SIGNOR-124060 |
| ATM | CREB1 | Ser107 | SVDSVTDsQKRREIL | phosphorylation down-regulates | 15073328 | SIGNOR-124047 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| ATR | phosphorylation up-regulates → | CREB1 PSer107 | phosphorylation down-regulates ⊣ | CREB1 | 15073328 | SIGNOR-124060 |
| ATM | phosphorylation up-regulates → | CREB1 PSer107 | phosphorylation down-regulates ⊣ | CREB1 | 15073328 | SIGNOR-124047 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| ATR | phosphorylation![]() down-regulates | CREB1 | SIGNOR-124060 |
| ATM | phosphorylation![]() down-regulates | CREB1 | SIGNOR-124047 |