| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | HMGA1 | Ser36 | PRKQPPVsPGTALVG | phosphorylation down-regulates | 17960875 | SIGNOR-158612 |
| CDK1 | HMGA1 | Ser36 | PRKQPPVsPGTALVG | phosphorylation down-regulates | 17960875 | SIGNOR-158604 |
| HIPK2 | HMGA1 | Ser36 | PRKQPPVsPGTALVG | phosphorylation down-regulates | 17960875 | SIGNOR-158616 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK2 | phosphorylation up-regulates → | HMGA1 PSer36 | phosphorylation down-regulates ⊣ | HMGA1 | 17960875 | SIGNOR-158612 |
| CDK1 | phosphorylation up-regulates → | HMGA1 PSer36 | phosphorylation down-regulates ⊣ | HMGA1 | 17960875 | SIGNOR-158604 |
| HIPK2 | phosphorylation up-regulates → | HMGA1 PSer36 | phosphorylation down-regulates ⊣ | HMGA1 | 17960875 | SIGNOR-158616 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK2 | phosphorylation![]() down-regulates | HMGA1 | SIGNOR-158612 |
| CDK1 | phosphorylation![]() down-regulates | HMGA1 | SIGNOR-158604 |
| HIPK2 | phosphorylation![]() down-regulates | HMGA1 | SIGNOR-158616 |