Entity Details

Name IFNAR1
ID P17181
Role substrate
Enzymatic Domains
Fibronectin type-III 1 32-126
PROSITE-ProRule
Fibronectin type-III 2 127-227
PROSITE-ProRule
Fibronectin type-III 3 231-329
PROSITE-ProRule
Fibronectin type-III 4 331-432
PROSITE-ProRule
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
TYK2IFNAR1Tyr466VFLRCINyVFFPSLKphosphorylation
up-regulates activity		8605876SIGNOR-246934
TYK2IFNAR1Tyr481PSSSIDEyFSEQPLKphosphorylation
up-regulates activity		7526154SIGNOR-246939
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
TYK2phosphorylation
up-regulates
→
IFNAR1
PTyr466		phosphorylation
up-regulates
→		IFNAR18605876SIGNOR-246934
TYK2phosphorylation
up-regulates
→
IFNAR1
PTyr481		phosphorylation
up-regulates
→		IFNAR17526154SIGNOR-246939
Regulator Mechanism/Effect Target SIGNOR-ID
TYK2phosphorylation
→
up-regulates activity 		IFNAR1SIGNOR-246934
TYK2phosphorylation
→
up-regulates activity 		IFNAR1SIGNOR-246939