Entity Details

Name TYK2_Tyr466
ID P17181
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
TYK2IFNAR1Tyr466VFLRCINyVFFPSLKphosphorylation
up-regulates activity		8605876SIGNOR-246934
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
TYK2phosphorylation
up-regulates
→
IFNAR1
PTyr466		phosphorylation
up-regulates
→		IFNAR18605876SIGNOR-246934
Regulator Mechanism/Effect Target SIGNOR-ID
TYK2phosphorylation
→
up-regulates activity 		IFNAR1SIGNOR-246934