Entity Details

Name PTPN2_Tyr247
ID P17302
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTPN2GJA1Tyr247VKGKSDPyHATSGALdephosphorylation
up-regulates		24849651SIGNOR-205097
SRCGJA1Tyr247VKGKSDPyHATSGALphosphorylation
down-regulates		16916748SIGNOR-148913
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTPN2dephosphorylation
down-regulates
⊣
GJA1
PTyr247		dephosphorylation
down-regulates
⊣		GJA124849651SIGNOR-205097
SRCphosphorylation
up-regulates
→
GJA1
PTyr247		phosphorylation
down-regulates
⊣		GJA116916748SIGNOR-148913
Regulator Mechanism/Effect Target SIGNOR-ID
PTPN2dephosphorylation
→
up-regulates 		GJA1SIGNOR-205097
SRCphosphorylation
img/direct_inhibition.png
down-regulates 		GJA1SIGNOR-148913