Summary

Name GJA1
Full Name Gap junction alpha-1 protein
Synonyms Connexin-43, Cx43, Gap junction 43 kDa heart protein | GJAL
Primary ID P17302
Links - -
Type protein
Relations 22
Function Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity

Viewer

Modifications Tables

Relations

Regulator Mechanism target score
+ down-regulates activity img/direct_inhibition.png phosphorylation GJA1 0.22
Publications: 3 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation GJA1 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation GJA1 0.22
Publications: 3 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation GJA1 0.2
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation GJA1 0.35
Publications: 3 Organism: Rattus Norvegicus
+ up-regulates img/direct-activation.png phosphorylation GJA1 0.14
Publications: 4 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation GJA1 0.28
Publications: 1 Organism: Rattus Norvegicus
+ down-regulates activity img/direct_inhibition.png phosphorylation GJA1 0.14
Publications: 1 Organism: Rattus Norvegicus
+ down-regulates activity img/direct_inhibition.png phosphorylation GJA1 0.2
Publications: 1 Organism: Rattus Norvegicus
+ down-regulates img/direct_inhibition.png phosphorylation GJA1 0.44
Publications: 2 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png dephosphorylation GJA1 0.14
Publications: 2 Organism: Homo Sapiens
Tissue: Kidney