Entity Details

Name PTPN2_Tyr265
ID P17302
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
PTPN2GJA1Tyr265KDCGSQKyAYFNGCSdephosphorylation
up-regulates		24849651SIGNOR-205101
SRCGJA1Tyr265KDCGSQKyAYFNGCSphosphorylation
down-regulates		16916748SIGNOR-148917
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
PTPN2dephosphorylation
down-regulates
⊣
GJA1
PTyr265		dephosphorylation
down-regulates
⊣		GJA124849651SIGNOR-205101
SRCphosphorylation
up-regulates
→
GJA1
PTyr265		phosphorylation
down-regulates
⊣		GJA116916748SIGNOR-148917
Regulator Mechanism/Effect Target SIGNOR-ID
PTPN2dephosphorylation
→
up-regulates 		GJA1SIGNOR-205101
SRCphosphorylation
img/direct_inhibition.png
down-regulates 		GJA1SIGNOR-148917