| Name | CEBPB |
| ID | P17676 |
| Role | substrate |
| Enzymatic Domains |
bZIP 271-334 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | CEBPB | Thr235 | SSSSPPGtPSPADAK | phosphorylation up-regulates activity | 22355693 | SIGNOR-251644 |
| CyclinA2/CDK2 | CEBPB | Thr235 | SSSSPPGtPSPADAK | phosphorylation up-regulates | 22369944 | SIGNOR-217316 |
| CyclinA2/CDK2 | CEBPB | Thr235 | SSSSPPGtPSPADAK | phosphorylation up-regulates | 17601773 | SIGNOR-217312 |
| MAPK3 | CEBPB | Thr235 | SSSSPPGtPSPADAK | phosphorylation up-regulates | 19327116 | SIGNOR-184917 |
| ABL2 | CEBPB | Tyr78 | RAIDFSPyLEPLGAP | phosphorylation up-regulates | 19563810 | SIGNOR-186427 |
| PAK4 | CEBPB | Thr235 | SSSSPPGtPSPADAK | phosphorylation up-regulates activity | 30808546 | SIGNOR-280055 |
| RPS6KA1 | CEBPB | – | phosphorylation up-regulates activity | 22068162 | SIGNOR-280112 | |
| GSK3B | CEBPB | Thr226 | GSSGSLStSSSSSPP | phosphorylation up-regulates | 22369944 | SIGNOR-210129 |
| CDK2 | CEBPB | Thr235 | SSSSPPGtPSPADAK | phosphorylation up-regulates | 22369944 | SIGNOR-196372 |
| CDK2 | CEBPB | Thr235 | SSSSPPGtPSPADAK | phosphorylation up-regulates | 17601773 | SIGNOR-156509 |
| ABL1 | CEBPB | Tyr78 | RAIDFSPyLEPLGAP | phosphorylation up-regulates | 19563810 | SIGNOR-186423 |
| CAMK2A | CEBPB | Ser325 | EQLSRELsTLRNLFK | phosphorylation up-regulates activity | 1314426 | SIGNOR-250617 |
| GSK3B | CEBPB | Ser231 | LSTSSSSsPPGTPSP | phosphorylation up-regulates | 22369944 | SIGNOR-196377 |
| MAPK1 | CEBPB | Thr235 | SSSSPPGtPSPADAK | phosphorylation up-regulates | 19723873 | SIGNOR-187798 |
| GSK3B | CEBPB | Ser231 | LSTSSSSsPPGTPSP | phosphorylation up-regulates | 17601773 | SIGNOR-156514 |
| Gbeta | CEBPB | – | phosphorylation up-regulates | 19327116 | SIGNOR-270045 | |
| ERK1/2 | CEBPB | Thr235 | SSSSPPGtPSPADAK | phosphorylation up-regulates activity | 19723873 | SIGNOR-238303 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| GSK3B | phosphorylation up-regulates → | CEBPB PThr235 | phosphorylation up-regulates → | CEBPB | 22355693 | SIGNOR-251644 |
| CyclinA2/CDK2 | phosphorylation up-regulates → | CEBPB PThr235 | phosphorylation up-regulates → | CEBPB | 22369944 | SIGNOR-217316 |
| CyclinA2/CDK2 | phosphorylation up-regulates → | CEBPB PThr235 | phosphorylation up-regulates → | CEBPB | 17601773 | SIGNOR-217312 |
| MAPK3 | phosphorylation up-regulates → | CEBPB PThr235 | phosphorylation up-regulates → | CEBPB | 19327116 | SIGNOR-184917 |
| ABL2 | phosphorylation up-regulates → | CEBPB PTyr78 | phosphorylation up-regulates → | CEBPB | 19563810 | SIGNOR-186427 |
| PAK4 | phosphorylation up-regulates → | CEBPB PThr235 | phosphorylation up-regulates → | CEBPB | 30808546 | SIGNOR-280055 |
| GSK3B | phosphorylation up-regulates → | CEBPB PThr226 | phosphorylation up-regulates → | CEBPB | 22369944 | SIGNOR-210129 |
| CDK2 | phosphorylation up-regulates → | CEBPB PThr235 | phosphorylation up-regulates → | CEBPB | 22369944 | SIGNOR-196372 |
| CDK2 | phosphorylation up-regulates → | CEBPB PThr235 | phosphorylation up-regulates → | CEBPB | 17601773 | SIGNOR-156509 |
| ABL1 | phosphorylation up-regulates → | CEBPB PTyr78 | phosphorylation up-regulates → | CEBPB | 19563810 | SIGNOR-186423 |
| CAMK2A | phosphorylation up-regulates → | CEBPB PSer325 | phosphorylation up-regulates → | CEBPB | 1314426 | SIGNOR-250617 |
| GSK3B | phosphorylation up-regulates → | CEBPB PSer231 | phosphorylation up-regulates → | CEBPB | 22369944 | SIGNOR-196377 |
| MAPK1 | phosphorylation up-regulates → | CEBPB PThr235 | phosphorylation up-regulates → | CEBPB | 19723873 | SIGNOR-187798 |
| GSK3B | phosphorylation up-regulates → | CEBPB PSer231 | phosphorylation up-regulates → | CEBPB | 17601773 | SIGNOR-156514 |
| ERK1/2 | phosphorylation up-regulates → | CEBPB PThr235 | phosphorylation up-regulates → | CEBPB | 19723873 | SIGNOR-238303 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| GSK3B | phosphorylation → up-regulates activity | CEBPB | SIGNOR-251644 |
| CyclinA2/CDK2 | phosphorylation → up-regulates | CEBPB | SIGNOR-217316 |
| CyclinA2/CDK2 | phosphorylation → up-regulates | CEBPB | SIGNOR-217312 |
| MAPK3 | phosphorylation → up-regulates | CEBPB | SIGNOR-184917 |
| ABL2 | phosphorylation → up-regulates | CEBPB | SIGNOR-186427 |
| PAK4 | phosphorylation → up-regulates activity | CEBPB | SIGNOR-280055 |
| RPS6KA1 | phosphorylation → up-regulates activity | CEBPB | SIGNOR-280112 |
| GSK3B | phosphorylation → up-regulates | CEBPB | SIGNOR-210129 |
| CDK2 | phosphorylation → up-regulates | CEBPB | SIGNOR-196372 |
| CDK2 | phosphorylation → up-regulates | CEBPB | SIGNOR-156509 |
| ABL1 | phosphorylation → up-regulates | CEBPB | SIGNOR-186423 |
| CAMK2A | phosphorylation → up-regulates activity | CEBPB | SIGNOR-250617 |
| GSK3B | phosphorylation → up-regulates | CEBPB | SIGNOR-196377 |
| MAPK1 | phosphorylation → up-regulates | CEBPB | SIGNOR-187798 |
| GSK3B | phosphorylation → up-regulates | CEBPB | SIGNOR-156514 |
| Gbeta | phosphorylation → up-regulates | CEBPB | SIGNOR-270045 |
| ERK1/2 | phosphorylation → up-regulates activity | CEBPB | SIGNOR-238303 |