| Name | ATF1 |
| ID | P18846 |
| Role | substrate |
| Enzymatic Domains |
KID 31-90 PROSITE-ProRule
bZIP 213-271 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| RPS6KA4 | ATF1 | – | phosphorylation up-regulates | 11909979 | SIGNOR-116252 | |
| PPP2R5C | ATF1 | Ser38 | QVSSLSEsEESQDSS | dephosphorylation up-regulates | 20730097 | SIGNOR-167564 |
| CSNK2A1 | ATF1 | Ser41 | SLSESEEsQDSSDSI | phosphorylation down-regulates | 20730097 | SIGNOR-167552 |
| PPP2R5C | ATF1 | Ser44 | ESEESQDsSDSIGSS | dephosphorylation up-regulates | 20730097 | SIGNOR-167572 |
| RPS6KA5 | ATF1 | Ser63 | GILARRPsYRKILKD | phosphorylation up-regulates activity | 11909979 | SIGNOR-249144 |
| PRKACA | ATF1 | Ser63 | GILARRPsYRKILKD | phosphorylation up-regulates activity | 9016641 | SIGNOR-250336 |
| CAMK1 | ATF1 | Ser63 | GILARRPsYRKILKD | phosphorylation up-regulates activity | 8663317 | SIGNOR-250611 |
| RPS6KA5 | ATF1 | Ser63 | GILARRPsYRKILKD | phosphorylation up-regulates activity | 12414794 | SIGNOR-95318 |
| RPS6KA4 | ATF1 | – | phosphorylation up-regulates | 20626350 | SIGNOR-166661 | |
| RPS6KA4 | ATF1 | Ser63 | GILARRPsYRKILKD | phosphorylation up-regulates activity | 11909979 | SIGNOR-249145 |
| CAMK2G | ATF1 | Ser63 | GILARRPsYRKILKD | phosphorylation up-regulates activity | 8663317 | SIGNOR-250692 |
| RPS6KA3 | ATF1 | – | phosphorylation up-regulates activity | 10723128 | SIGNOR-280117 | |
| ATM | ATF1 | Ser51 | SSDSIGSsQKAHGIL | phosphorylation up-regulates activity | 20730097 | SIGNOR-278909 |
| CSNK2A1 | ATF1 | Ser44 | ESEESQDsSDSIGSS | phosphorylation down-regulates | 20730097 | SIGNOR-167556 |
| PPP2R5C | ATF1 | Ser41 | SLSESEEsQDSSDSI | dephosphorylation up-regulates | 20730097 | SIGNOR-167568 |
| CDK3 | ATF1 | Ser63 | GILARRPsYRKILKD | phosphorylation up-regulates | 18794154 | SIGNOR-180920 |
| CSNK2A1 | ATF1 | Ser63 | GILARRPsYRKILKD | phosphorylation up-regulates | 8663317 | SIGNOR-42565 |
| CSNK2A1 | ATF1 | Ser36 | AQQVSSLsESEESQD | phosphorylation down-regulates | 20730097 | SIGNOR-167544 |
| PPP2R5C | ATF1 | Ser36 | AQQVSSLsESEESQD | dephosphorylation up-regulates | 20730097 | SIGNOR-167560 |
| CSNK2A1 | ATF1 | Ser38 | QVSSLSEsEESQDSS | phosphorylation down-regulates | 20730097 | SIGNOR-167548 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PPP2R5C | dephosphorylation down-regulates ⊣ | ATF1 PSer38 | dephosphorylation down-regulates ⊣ | ATF1 | 20730097 | SIGNOR-167564 |
| CSNK2A1 | phosphorylation up-regulates → | ATF1 PSer41 | phosphorylation down-regulates ⊣ | ATF1 | 20730097 | SIGNOR-167552 |
| PPP2R5C | dephosphorylation down-regulates ⊣ | ATF1 PSer44 | dephosphorylation down-regulates ⊣ | ATF1 | 20730097 | SIGNOR-167572 |
| RPS6KA5 | phosphorylation up-regulates → | ATF1 PSer63 | phosphorylation up-regulates → | ATF1 | 11909979 | SIGNOR-249144 |
| PRKACA | phosphorylation up-regulates → | ATF1 PSer63 | phosphorylation up-regulates → | ATF1 | 9016641 | SIGNOR-250336 |
| CAMK1 | phosphorylation up-regulates → | ATF1 PSer63 | phosphorylation up-regulates → | ATF1 | 8663317 | SIGNOR-250611 |
| RPS6KA5 | phosphorylation up-regulates → | ATF1 PSer63 | phosphorylation up-regulates → | ATF1 | 12414794 | SIGNOR-95318 |
| RPS6KA4 | phosphorylation up-regulates → | ATF1 PSer63 | phosphorylation up-regulates → | ATF1 | 11909979 | SIGNOR-249145 |
| CAMK2G | phosphorylation up-regulates → | ATF1 PSer63 | phosphorylation up-regulates → | ATF1 | 8663317 | SIGNOR-250692 |
| ATM | phosphorylation up-regulates → | ATF1 PSer51 | phosphorylation up-regulates → | ATF1 | 20730097 | SIGNOR-278909 |
| CSNK2A1 | phosphorylation up-regulates → | ATF1 PSer44 | phosphorylation down-regulates ⊣ | ATF1 | 20730097 | SIGNOR-167556 |
| PPP2R5C | dephosphorylation down-regulates ⊣ | ATF1 PSer41 | dephosphorylation down-regulates ⊣ | ATF1 | 20730097 | SIGNOR-167568 |
| CDK3 | phosphorylation up-regulates → | ATF1 PSer63 | phosphorylation up-regulates → | ATF1 | 18794154 | SIGNOR-180920 |
| CSNK2A1 | phosphorylation up-regulates → | ATF1 PSer63 | phosphorylation up-regulates → | ATF1 | 8663317 | SIGNOR-42565 |
| CSNK2A1 | phosphorylation up-regulates → | ATF1 PSer36 | phosphorylation down-regulates ⊣ | ATF1 | 20730097 | SIGNOR-167544 |
| PPP2R5C | dephosphorylation down-regulates ⊣ | ATF1 PSer36 | dephosphorylation down-regulates ⊣ | ATF1 | 20730097 | SIGNOR-167560 |
| CSNK2A1 | phosphorylation up-regulates → | ATF1 PSer38 | phosphorylation down-regulates ⊣ | ATF1 | 20730097 | SIGNOR-167548 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| RPS6KA4 | phosphorylation → up-regulates | ATF1 | SIGNOR-116252 |
| PPP2R5C | dephosphorylation → up-regulates | ATF1 | SIGNOR-167564 |
| CSNK2A1 | phosphorylation down-regulates | ATF1 | SIGNOR-167552 |
| PPP2R5C | dephosphorylation → up-regulates | ATF1 | SIGNOR-167572 |
| RPS6KA5 | phosphorylation → up-regulates activity | ATF1 | SIGNOR-249144 |
| PRKACA | phosphorylation → up-regulates activity | ATF1 | SIGNOR-250336 |
| CAMK1 | phosphorylation → up-regulates activity | ATF1 | SIGNOR-250611 |
| RPS6KA5 | phosphorylation → up-regulates activity | ATF1 | SIGNOR-95318 |
| RPS6KA4 | phosphorylation → up-regulates | ATF1 | SIGNOR-166661 |
| RPS6KA4 | phosphorylation → up-regulates activity | ATF1 | SIGNOR-249145 |
| CAMK2G | phosphorylation → up-regulates activity | ATF1 | SIGNOR-250692 |
| RPS6KA3 | phosphorylation → up-regulates activity | ATF1 | SIGNOR-280117 |
| ATM | phosphorylation → up-regulates activity | ATF1 | SIGNOR-278909 |
| CSNK2A1 | phosphorylation down-regulates | ATF1 | SIGNOR-167556 |
| PPP2R5C | dephosphorylation → up-regulates | ATF1 | SIGNOR-167568 |
| CDK3 | phosphorylation → up-regulates | ATF1 | SIGNOR-180920 |
| CSNK2A1 | phosphorylation → up-regulates | ATF1 | SIGNOR-42565 |
| CSNK2A1 | phosphorylation down-regulates | ATF1 | SIGNOR-167544 |
| PPP2R5C | dephosphorylation → up-regulates | ATF1 | SIGNOR-167560 |
| CSNK2A1 | phosphorylation down-regulates | ATF1 | SIGNOR-167548 |