| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | ELK1 | Thr336 | GGPGPERtPGSGSGS | phosphorylation up-regulates | 7889942 | SIGNOR-235467 |
| MAPK3 | ELK1 | Thr336 | GGPGPERtPGSGSGS | phosphorylation up-regulates | 7889942 | SIGNOR-34669 |
| ERK1/2 | ELK1 | Thr336 | GGPGPERtPGSGSGS | phosphorylation up-regulates | 7889942 | SIGNOR-252082 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | ELK1 PThr336 | phosphorylation up-regulates → | ELK1 | 7889942 | SIGNOR-235467 |
| MAPK3 | phosphorylation up-regulates → | ELK1 PThr336 | phosphorylation up-regulates → | ELK1 | 7889942 | SIGNOR-34669 |
| ERK1/2 | phosphorylation up-regulates → | ELK1 PThr336 | phosphorylation up-regulates → | ELK1 | 7889942 | SIGNOR-252082 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation → up-regulates | ELK1 | SIGNOR-235467 |
| MAPK3 | phosphorylation → up-regulates | ELK1 | SIGNOR-34669 |
| ERK1/2 | phosphorylation → up-regulates | ELK1 | SIGNOR-252082 |
