| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK14 | ELK1 | Ser383 | IHFWSTLsPIAPRSP | phosphorylation up-regulates | 11145955 | SIGNOR-85510 |
| MAPK14 | ELK1 | Ser383 | IHFWSTLsPIAPRSP | phosphorylation up-regulates | 20727996 | SIGNOR-167539 |
| ERK1/2 | ELK1 | Ser383 | IHFWSTLsPIAPRSP | phosphorylation up-regulates | 7889942 | SIGNOR-252083 |
| MAPK1 | ELK1 | Ser383 | IHFWSTLsPIAPRSP | phosphorylation up-regulates activity | 7889942 | SIGNOR-235455 |
| TAOK2 | ELK1 | Ser383 | IHFWSTLsPIAPRSP | phosphorylation up-regulates activity | 12665513 | SIGNOR-246638 |
| MAPK3 | ELK1 | Ser383 | IHFWSTLsPIAPRSP | phosphorylation up-regulates | 7889942 | SIGNOR-34657 |
| RPS6KA5 | ELK1 | Ser383 | IHFWSTLsPIAPRSP | phosphorylation up-regulates | 11145955 | SIGNOR-85514 |
| MAPK14 | ELK1 | Ser383 | IHFWSTLsPIAPRSP | phosphorylation up-regulates | 9130707 | SIGNOR-47630 |
| MAPK8 | ELK1 | Ser383 | IHFWSTLsPIAPRSP | phosphorylation up-regulates | 8846788 | SIGNOR-44356 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK14 | phosphorylation up-regulates → | ELK1 PSer383 | phosphorylation up-regulates → | ELK1 | 11145955 | SIGNOR-85510 |
| MAPK14 | phosphorylation up-regulates → | ELK1 PSer383 | phosphorylation up-regulates → | ELK1 | 20727996 | SIGNOR-167539 |
| ERK1/2 | phosphorylation up-regulates → | ELK1 PSer383 | phosphorylation up-regulates → | ELK1 | 7889942 | SIGNOR-252083 |
| MAPK1 | phosphorylation up-regulates → | ELK1 PSer383 | phosphorylation up-regulates → | ELK1 | 7889942 | SIGNOR-235455 |
| TAOK2 | phosphorylation up-regulates → | ELK1 PSer383 | phosphorylation up-regulates → | ELK1 | 12665513 | SIGNOR-246638 |
| MAPK3 | phosphorylation up-regulates → | ELK1 PSer383 | phosphorylation up-regulates → | ELK1 | 7889942 | SIGNOR-34657 |
| RPS6KA5 | phosphorylation up-regulates → | ELK1 PSer383 | phosphorylation up-regulates → | ELK1 | 11145955 | SIGNOR-85514 |
| MAPK14 | phosphorylation up-regulates → | ELK1 PSer383 | phosphorylation up-regulates → | ELK1 | 9130707 | SIGNOR-47630 |
| MAPK8 | phosphorylation up-regulates → | ELK1 PSer383 | phosphorylation up-regulates → | ELK1 | 8846788 | SIGNOR-44356 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK14 | phosphorylation → up-regulates | ELK1 | SIGNOR-85510 |
| MAPK14 | phosphorylation → up-regulates | ELK1 | SIGNOR-167539 |
| ERK1/2 | phosphorylation → up-regulates | ELK1 | SIGNOR-252083 |
| MAPK1 | phosphorylation → up-regulates activity | ELK1 | SIGNOR-235455 |
| TAOK2 | phosphorylation → up-regulates activity | ELK1 | SIGNOR-246638 |
| MAPK3 | phosphorylation → up-regulates | ELK1 | SIGNOR-34657 |
| RPS6KA5 | phosphorylation → up-regulates | ELK1 | SIGNOR-85514 |
| MAPK14 | phosphorylation → up-regulates | ELK1 | SIGNOR-47630 |
| MAPK8 | phosphorylation → up-regulates | ELK1 | SIGNOR-44356 |
