Entity Details

Name MAPK1_Ser142
ID P19484
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MTORTFEBSer142AGNSAPNsPMAMLHIphosphorylation
down-regulates activity		22343943SIGNOR-255310
PPP3CBTFEBSer142AGNSAPNsPMAMLHIdephosphorylation
up-regulates activity		26000950SIGNOR-255307
mTORC1TFEBSer142AGNSAPNsPMAMLHIphosphorylation
down-regulates activity		22343943SIGNOR-255309
MAPK1TFEBSer142AGNSAPNsPMAMLHIphosphorylation
down-regulates activity		21617040SIGNOR-248279
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MTORphosphorylation
up-regulates
→
TFEB
PSer142		phosphorylation
down-regulates
⊣		TFEB22343943SIGNOR-255310
PPP3CBdephosphorylation
down-regulates
⊣
TFEB
PSer142		dephosphorylation
down-regulates
⊣		TFEB26000950SIGNOR-255307
mTORC1phosphorylation
up-regulates
→
TFEB
PSer142		phosphorylation
down-regulates
⊣		TFEB22343943SIGNOR-255309
MAPK1phosphorylation
up-regulates
→
TFEB
PSer142		phosphorylation
down-regulates
⊣		TFEB21617040SIGNOR-248279
Regulator Mechanism/Effect Target SIGNOR-ID
MTORphosphorylation
→
down-regulates activity 		TFEBSIGNOR-255310
PPP3CBdephosphorylation
→
up-regulates activity 		TFEBSIGNOR-255307
mTORC1phosphorylation
→
down-regulates activity 		TFEBSIGNOR-255309
MAPK1phosphorylation
→
down-regulates activity 		TFEBSIGNOR-248279