Entity Details

Name TFEB_Ser142
ID P19484
Role residue
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK1TFEBSer142AGNSAPNsPMAMLHIphosphorylation
down-regulates activity
21617040SIGNOR-248279
PPP3CBTFEBSer142AGNSAPNsPMAMLHIdephosphorylation
up-regulates activity
26000950SIGNOR-255307
mTORC1TFEBSer142AGNSAPNsPMAMLHIphosphorylation
down-regulates activity
22343943SIGNOR-255309
MTORTFEBSer142AGNSAPNsPMAMLHIphosphorylation
down-regulates activity
22343943SIGNOR-255310
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK1phosphorylation
up-regulates
→
TFEB
PSer142
phosphorylation
down-regulates
⊣
TFEB21617040SIGNOR-248279
PPP3CBdephosphorylation
down-regulates
⊣
TFEB
PSer142
dephosphorylation
down-regulates
⊣
TFEB26000950SIGNOR-255307
mTORC1phosphorylation
up-regulates
→
TFEB
PSer142
phosphorylation
down-regulates
⊣
TFEB22343943SIGNOR-255309
MTORphosphorylation
up-regulates
→
TFEB
PSer142
phosphorylation
down-regulates
⊣
TFEB22343943SIGNOR-255310
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK1phosphorylation
→
down-regulates activity
TFEBSIGNOR-248279
PPP3CBdephosphorylation
→
up-regulates activity
TFEBSIGNOR-255307
mTORC1phosphorylation
→
down-regulates activity
TFEBSIGNOR-255309
MTORphosphorylation
→
down-regulates activity
TFEBSIGNOR-255310