| Name | RXRA |
| ID | P19793 |
| Role | substrate |
| Enzymatic Domains |
NR LBD 227-458 PROSITE-ProRule |
View in ![]() |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK9 | RXRA | Ser260 | NMGLNPSsPNDPVTN | phosphorylation down-regulates activity | 16551633 | SIGNOR-145301 |
| GSK3B | RXRA | Ser49 | GSPGQLHsPISTLSS | phosphorylation up-regulates activity | 29137318 | SIGNOR-277372 |
| MAP2K4 | RXRA | Tyr249 | VEPKTETyVEANMGL | phosphorylation down-regulates | 10938283 | SIGNOR-80619 |
| GSK3B | RXRA | Ser66 | NGMGPPFsVISSPMG | phosphorylation up-regulates activity | 29137318 | SIGNOR-277370 |
| MAPK3 | RXRA | Thr82 | HSMSVPTtPTLGFST | phosphorylation down-regulates activity | 17604322 | SIGNOR-262959 |
| MAPK1 | RXRA | Thr82 | HSMSVPTtPTLGFST | phosphorylation down-regulates activity | 17604322 | SIGNOR-262958 |
| MAPK3 | RXRA | Ser260 | NMGLNPSsPNDPVTN | phosphorylation down-regulates activity | 17604322 | SIGNOR-88662 |
| Gbeta | RXRA | – | phosphorylation down-regulates activity | 17604322 | SIGNOR-269995 | |
| MAPK8 | RXRA | Ser260 | NMGLNPSsPNDPVTN | phosphorylation down-regulates activity | 16551633 | SIGNOR-145297 |
| GSK3B | RXRA | Ser78 | PMGPHSMsVPTTPTL | phosphorylation up-regulates activity | 29137318 | SIGNOR-277371 |
| ERK1/2 | RXRA | Thr82 | HSMSVPTtPTLGFST | phosphorylation down-regulates activity | 17604322 | SIGNOR-262960 |
| PRKACA | RXRA | Ser27 | TSPTGRGsMAAPSLH | phosphorylation down-regulates | 11162439 | SIGNOR-104954 |
| ERK1/2 | RXRA | Ser260 | NMGLNPSsPNDPVTN | phosphorylation down-regulates activity | 17604322 | SIGNOR-244573 |
| MAPK1 | RXRA | Ser260 | NMGLNPSsPNDPVTN | phosphorylation down-regulates activity | 17604322 | SIGNOR-88658 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK9 | phosphorylation up-regulates → | RXRA PSer260 | phosphorylation down-regulates ⊣ | RXRA | 16551633 | SIGNOR-145301 |
| GSK3B | phosphorylation up-regulates → | RXRA PSer49 | phosphorylation up-regulates → | RXRA | 29137318 | SIGNOR-277372 |
| MAP2K4 | phosphorylation up-regulates → | RXRA PTyr249 | phosphorylation down-regulates ⊣ | RXRA | 10938283 | SIGNOR-80619 |
| GSK3B | phosphorylation up-regulates → | RXRA PSer66 | phosphorylation up-regulates → | RXRA | 29137318 | SIGNOR-277370 |
| MAPK3 | phosphorylation up-regulates → | RXRA PThr82 | phosphorylation down-regulates ⊣ | RXRA | 17604322 | SIGNOR-262959 |
| MAPK1 | phosphorylation up-regulates → | RXRA PThr82 | phosphorylation down-regulates ⊣ | RXRA | 17604322 | SIGNOR-262958 |
| MAPK3 | phosphorylation up-regulates → | RXRA PSer260 | phosphorylation down-regulates ⊣ | RXRA | 17604322 | SIGNOR-88662 |
| MAPK8 | phosphorylation up-regulates → | RXRA PSer260 | phosphorylation down-regulates ⊣ | RXRA | 16551633 | SIGNOR-145297 |
| GSK3B | phosphorylation up-regulates → | RXRA PSer78 | phosphorylation up-regulates → | RXRA | 29137318 | SIGNOR-277371 |
| ERK1/2 | phosphorylation up-regulates → | RXRA PThr82 | phosphorylation down-regulates ⊣ | RXRA | 17604322 | SIGNOR-262960 |
| PRKACA | phosphorylation up-regulates → | RXRA PSer27 | phosphorylation down-regulates ⊣ | RXRA | 11162439 | SIGNOR-104954 |
| ERK1/2 | phosphorylation up-regulates → | RXRA PSer260 | phosphorylation down-regulates ⊣ | RXRA | 17604322 | SIGNOR-244573 |
| MAPK1 | phosphorylation up-regulates → | RXRA PSer260 | phosphorylation down-regulates ⊣ | RXRA | 17604322 | SIGNOR-88658 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK9 | phosphorylation → down-regulates activity | RXRA | SIGNOR-145301 |
| GSK3B | phosphorylation → up-regulates activity | RXRA | SIGNOR-277372 |
| MAP2K4 | phosphorylation![]() down-regulates | RXRA | SIGNOR-80619 |
| GSK3B | phosphorylation → up-regulates activity | RXRA | SIGNOR-277370 |
| MAPK3 | phosphorylation → down-regulates activity | RXRA | SIGNOR-262959 |
| MAPK1 | phosphorylation → down-regulates activity | RXRA | SIGNOR-262958 |
| MAPK3 | phosphorylation → down-regulates activity | RXRA | SIGNOR-88662 |
| Gbeta | phosphorylation → down-regulates activity | RXRA | SIGNOR-269995 |
| MAPK8 | phosphorylation → down-regulates activity | RXRA | SIGNOR-145297 |
| GSK3B | phosphorylation → up-regulates activity | RXRA | SIGNOR-277371 |
| ERK1/2 | phosphorylation → down-regulates activity | RXRA | SIGNOR-262960 |
| PRKACA | phosphorylation![]() down-regulates | RXRA | SIGNOR-104954 |
| ERK1/2 | phosphorylation → down-regulates activity | RXRA | SIGNOR-244573 |
| MAPK1 | phosphorylation → down-regulates activity | RXRA | SIGNOR-88658 |