Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MAPK1	RXRA	Ser260 View in OncoXplorer	NMGLNPSsPNDPVTN	phosphorylation down-regulates activity	17604322	SIGNOR-88658
MAPK1	RXRA	Thr82	HSMSVPTtPTLGFST	phosphorylation down-regulates activity	17604322	SIGNOR-262958
ERK1/2	RXRA	Ser260 View in OncoXplorer	NMGLNPSsPNDPVTN	phosphorylation down-regulates activity	17604322	SIGNOR-244573
MAPK8	RXRA	Ser260 View in OncoXplorer	NMGLNPSsPNDPVTN	phosphorylation down-regulates activity	16551633	SIGNOR-145297
GSK3B	RXRA	Ser49	GSPGQLHsPISTLSS	phosphorylation up-regulates activity	29137318	SIGNOR-277372
MAPK3	RXRA	Thr82	HSMSVPTtPTLGFST	phosphorylation down-regulates activity	17604322	SIGNOR-262959
GSK3B	RXRA	Ser78	PMGPHSMsVPTTPTL	phosphorylation up-regulates activity	29137318	SIGNOR-277371
MAPK9	RXRA	Ser260 View in OncoXplorer	NMGLNPSsPNDPVTN	phosphorylation down-regulates activity	16551633	SIGNOR-145301
Gbeta	RXRA	–		phosphorylation down-regulates activity	17604322	SIGNOR-269995
MAP2K4	RXRA	Tyr249	VEPKTETyVEANMGL	phosphorylation down-regulates	10938283	SIGNOR-80619
GSK3B	RXRA	Ser66	NGMGPPFsVISSPMG	phosphorylation up-regulates activity	29137318	SIGNOR-277370
PRKACA	RXRA	Ser27	TSPTGRGsMAAPSLH	phosphorylation down-regulates	11162439	SIGNOR-104954
ERK1/2	RXRA	Thr82	HSMSVPTtPTLGFST	phosphorylation down-regulates activity	17604322	SIGNOR-262960
MAPK3	RXRA	Ser260 View in OncoXplorer	NMGLNPSsPNDPVTN	phosphorylation down-regulates activity	17604322	SIGNOR-88662

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAPK1	phosphorylation up-regulates →	RXRA PSer260	phosphorylation down-regulates ⊣	RXRA	17604322	SIGNOR-88658
MAPK1	phosphorylation up-regulates →	RXRA PThr82	phosphorylation down-regulates ⊣	RXRA	17604322	SIGNOR-262958
ERK1/2	phosphorylation up-regulates →	RXRA PSer260	phosphorylation down-regulates ⊣	RXRA	17604322	SIGNOR-244573
MAPK8	phosphorylation up-regulates →	RXRA PSer260	phosphorylation down-regulates ⊣	RXRA	16551633	SIGNOR-145297
GSK3B	phosphorylation up-regulates →	RXRA PSer49	phosphorylation up-regulates →	RXRA	29137318	SIGNOR-277372
MAPK3	phosphorylation up-regulates →	RXRA PThr82	phosphorylation down-regulates ⊣	RXRA	17604322	SIGNOR-262959
GSK3B	phosphorylation up-regulates →	RXRA PSer78	phosphorylation up-regulates →	RXRA	29137318	SIGNOR-277371
MAPK9	phosphorylation up-regulates →	RXRA PSer260	phosphorylation down-regulates ⊣	RXRA	16551633	SIGNOR-145301
MAP2K4	phosphorylation up-regulates →	RXRA PTyr249	phosphorylation down-regulates ⊣	RXRA	10938283	SIGNOR-80619
GSK3B	phosphorylation up-regulates →	RXRA PSer66	phosphorylation up-regulates →	RXRA	29137318	SIGNOR-277370
PRKACA	phosphorylation up-regulates →	RXRA PSer27	phosphorylation down-regulates ⊣	RXRA	11162439	SIGNOR-104954
ERK1/2	phosphorylation up-regulates →	RXRA PThr82	phosphorylation down-regulates ⊣	RXRA	17604322	SIGNOR-262960
MAPK3	phosphorylation up-regulates →	RXRA PSer260	phosphorylation down-regulates ⊣	RXRA	17604322	SIGNOR-88662

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MAPK1	phosphorylation → down-regulates activity	RXRA	SIGNOR-88658
MAPK1	phosphorylation → down-regulates activity	RXRA	SIGNOR-262958
ERK1/2	phosphorylation → down-regulates activity	RXRA	SIGNOR-244573
MAPK8	phosphorylation → down-regulates activity	RXRA	SIGNOR-145297
GSK3B	phosphorylation → up-regulates activity	RXRA	SIGNOR-277372
MAPK3	phosphorylation → down-regulates activity	RXRA	SIGNOR-262959
GSK3B	phosphorylation → up-regulates activity	RXRA	SIGNOR-277371
MAPK9	phosphorylation → down-regulates activity	RXRA	SIGNOR-145301
Gbeta	phosphorylation → down-regulates activity	RXRA	SIGNOR-269995
MAP2K4	phosphorylation down-regulates	RXRA	SIGNOR-80619
GSK3B	phosphorylation → up-regulates activity	RXRA	SIGNOR-277370
PRKACA	phosphorylation down-regulates	RXRA	SIGNOR-104954
ERK1/2	phosphorylation → down-regulates activity	RXRA	SIGNOR-262960
MAPK3	phosphorylation → down-regulates activity	RXRA	SIGNOR-88662