Entity Details

Name MAPK8_Ser260
ID P19793
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
MAPK8RXRASer260NMGLNPSsPNDPVTNphosphorylation
down-regulates activity		16551633SIGNOR-145297
ERK1/2RXRASer260NMGLNPSsPNDPVTNphosphorylation
down-regulates activity		17604322SIGNOR-244573
MAPK1RXRASer260NMGLNPSsPNDPVTNphosphorylation
down-regulates activity		17604322SIGNOR-88658
MAPK9RXRASer260NMGLNPSsPNDPVTNphosphorylation
down-regulates activity		16551633SIGNOR-145301
MAPK3RXRASer260NMGLNPSsPNDPVTNphosphorylation
down-regulates activity		17604322SIGNOR-88662
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
MAPK8phosphorylation
up-regulates
→
RXRA
PSer260		phosphorylation
down-regulates
⊣		RXRA16551633SIGNOR-145297
ERK1/2phosphorylation
up-regulates
→
RXRA
PSer260		phosphorylation
down-regulates
⊣		RXRA17604322SIGNOR-244573
MAPK1phosphorylation
up-regulates
→
RXRA
PSer260		phosphorylation
down-regulates
⊣		RXRA17604322SIGNOR-88658
MAPK9phosphorylation
up-regulates
→
RXRA
PSer260		phosphorylation
down-regulates
⊣		RXRA16551633SIGNOR-145301
MAPK3phosphorylation
up-regulates
→
RXRA
PSer260		phosphorylation
down-regulates
⊣		RXRA17604322SIGNOR-88662
Regulator Mechanism/Effect Target SIGNOR-ID
MAPK8phosphorylation
→
down-regulates activity 		RXRASIGNOR-145297
ERK1/2phosphorylation
→
down-regulates activity 		RXRASIGNOR-244573
MAPK1phosphorylation
→
down-regulates activity 		RXRASIGNOR-88658
MAPK9phosphorylation
→
down-regulates activity 		RXRASIGNOR-145301
MAPK3phosphorylation
→
down-regulates activity 		RXRASIGNOR-88662