| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | RXRA | Ser260 | NMGLNPSsPNDPVTN | phosphorylation down-regulates activity | 17604322 | SIGNOR-88658 |
| ERK1/2 | RXRA | Ser260 | NMGLNPSsPNDPVTN | phosphorylation down-regulates activity | 17604322 | SIGNOR-244573 |
| MAPK8 | RXRA | Ser260 | NMGLNPSsPNDPVTN | phosphorylation down-regulates activity | 16551633 | SIGNOR-145297 |
| MAPK9 | RXRA | Ser260 | NMGLNPSsPNDPVTN | phosphorylation down-regulates activity | 16551633 | SIGNOR-145301 |
| MAPK3 | RXRA | Ser260 | NMGLNPSsPNDPVTN | phosphorylation down-regulates activity | 17604322 | SIGNOR-88662 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | RXRA PSer260 | phosphorylation down-regulates ⊣ | RXRA | 17604322 | SIGNOR-88658 |
| ERK1/2 | phosphorylation up-regulates → | RXRA PSer260 | phosphorylation down-regulates ⊣ | RXRA | 17604322 | SIGNOR-244573 |
| MAPK8 | phosphorylation up-regulates → | RXRA PSer260 | phosphorylation down-regulates ⊣ | RXRA | 16551633 | SIGNOR-145297 |
| MAPK9 | phosphorylation up-regulates → | RXRA PSer260 | phosphorylation down-regulates ⊣ | RXRA | 16551633 | SIGNOR-145301 |
| MAPK3 | phosphorylation up-regulates → | RXRA PSer260 | phosphorylation down-regulates ⊣ | RXRA | 17604322 | SIGNOR-88662 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation → down-regulates activity | RXRA | SIGNOR-88658 |
| ERK1/2 | phosphorylation → down-regulates activity | RXRA | SIGNOR-244573 |
| MAPK8 | phosphorylation → down-regulates activity | RXRA | SIGNOR-145297 |
| MAPK9 | phosphorylation → down-regulates activity | RXRA | SIGNOR-145301 |
| MAPK3 | phosphorylation → down-regulates activity | RXRA | SIGNOR-88662 |
