| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | RPS6KB1 | Ser447 | GSPRTPVsPVKFSPG | phosphorylation up-regulates | 21035469 | SIGNOR-169154 |
| MAPK1 | RPS6KB1 | Ser447 | GSPRTPVsPVKFSPG | phosphorylation up-regulates | 19085255 | SIGNOR-182808 |
| MAPK1 | RPS6KB1 | Ser447 | GSPRTPVsPVKFSPG | phosphorylation up-regulates | 7545671 | SIGNOR-28800 |
| MAPK1 | RPS6KB1 | Ser447 | GSPRTPVsPVKFSPG | phosphorylation up-regulates | 14967450 | SIGNOR-121988 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| MAPK1 | phosphorylation up-regulates → | RPS6KB1 PSer447 | phosphorylation up-regulates → | RPS6KB1 | 21035469 | SIGNOR-169154 |
| MAPK1 | phosphorylation up-regulates → | RPS6KB1 PSer447 | phosphorylation up-regulates → | RPS6KB1 | 19085255 | SIGNOR-182808 |
| MAPK1 | phosphorylation up-regulates → | RPS6KB1 PSer447 | phosphorylation up-regulates → | RPS6KB1 | 7545671 | SIGNOR-28800 |
| MAPK1 | phosphorylation up-regulates → | RPS6KB1 PSer447 | phosphorylation up-regulates → | RPS6KB1 | 14967450 | SIGNOR-121988 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| MAPK1 | phosphorylation → up-regulates | RPS6KB1 | SIGNOR-169154 |
| MAPK1 | phosphorylation → up-regulates | RPS6KB1 | SIGNOR-182808 |
| MAPK1 | phosphorylation → up-regulates | RPS6KB1 | SIGNOR-28800 |
| MAPK1 | phosphorylation → up-regulates | RPS6KB1 | SIGNOR-121988 |
