| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDPK1 | RPS6KB1 | Thr252 | HDGTVTHtFCGTIEY | phosphorylation up-regulates | 19864428 | SIGNOR-188907 |
| PDPK1 | RPS6KB1 | Thr252 | HDGTVTHtFCGTIEY | phosphorylation up-regulates activity | 9445476 | SIGNOR-243338 |
| PDPK1 | RPS6KB1 | Thr252 | HDGTVTHtFCGTIEY | phosphorylation up-regulates | 9445476 | SIGNOR-55306 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PDPK1 | phosphorylation up-regulates → | RPS6KB1 PThr252 | phosphorylation up-regulates → | RPS6KB1 | 19864428 | SIGNOR-188907 |
| PDPK1 | phosphorylation up-regulates → | RPS6KB1 PThr252 | phosphorylation up-regulates → | RPS6KB1 | 9445476 | SIGNOR-243338 |
| PDPK1 | phosphorylation up-regulates → | RPS6KB1 PThr252 | phosphorylation up-regulates → | RPS6KB1 | 9445476 | SIGNOR-55306 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PDPK1 | phosphorylation → up-regulates | RPS6KB1 | SIGNOR-188907 |
| PDPK1 | phosphorylation → up-regulates activity | RPS6KB1 | SIGNOR-243338 |
| PDPK1 | phosphorylation → up-regulates | RPS6KB1 | SIGNOR-55306 |
