| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK1B | CCND1 | Thr288 | VDLACTPtDVRDVDI | phosphorylation down-regulates | 17046823 | SIGNOR-150126 |
| DYRK1B | CCND1 | Thr288 | VDLACTPtDVRDVDI | phosphorylation down-regulates | 15546868 | SIGNOR-235801 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| DYRK1B | phosphorylation up-regulates → | CCND1 PThr288 | phosphorylation down-regulates ⊣ | CCND1 | 17046823 | SIGNOR-150126 |
| DYRK1B | phosphorylation up-regulates → | CCND1 PThr288 | phosphorylation down-regulates ⊣ | CCND1 | 15546868 | SIGNOR-235801 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| DYRK1B | phosphorylation![]() down-regulates | CCND1 | SIGNOR-150126 |
| DYRK1B | phosphorylation![]() down-regulates | CCND1 | SIGNOR-235801 |