| Name | IL4R |
| ID | P24394 |
| Role | kinase |
| Enzymatic Domains |
Fibronectin type-III 125-224 PROSITE-ProRule |
View in  |
|
| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| IL4R | JAK2 | – | phosphorylation up-regulates activity | 18852293 | SIGNOR-249530 | |
| IL4R | JAK1 | – | phosphorylation up-regulates activity | 23124025 | SIGNOR-249529 | |
| IL4R | IRS1 | – | phosphorylation up-regulates | 12704343 | SIGNOR-100768 | |
| IL4R | IRS2 | – | phosphorylation up-regulates | 12704343 | SIGNOR-100771 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| IL4R | phosphorylation → up-regulates activity | JAK2 | SIGNOR-249530 |
| IL4R | phosphorylation → up-regulates activity | JAK1 | SIGNOR-249529 |
| IL4R | phosphorylation → up-regulates | IRS1 | SIGNOR-100768 |
| IL4R | phosphorylation → up-regulates | IRS2 | SIGNOR-100771 |