| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BMX | F2R | Tyr383 | SECQRYVySILCCKE | phosphorylation down-regulates activity | 31910739 | SIGNOR-279594 |
| STK11 | F2R | – | phosphorylation up-regulates activity | 23271647 | SIGNOR-278992 | |
| BMX | F2R | Tyr381 | ASSECQRyVYSILCC | phosphorylation down-regulates activity | 31910739 | SIGNOR-279593 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| BMX | phosphorylation up-regulates → | F2R PTyr383 | phosphorylation down-regulates ⊣ | F2R | 31910739 | SIGNOR-279594 |
| BMX | phosphorylation up-regulates → | F2R PTyr381 | phosphorylation down-regulates ⊣ | F2R | 31910739 | SIGNOR-279593 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| BMX | phosphorylation → down-regulates activity | F2R | SIGNOR-279594 |
| STK11 | phosphorylation → up-regulates activity | F2R | SIGNOR-278992 |
| BMX | phosphorylation → down-regulates activity | F2R | SIGNOR-279593 |