Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
CDK2	MCM3	Thr722 View in OncoXplorer	EEMPQVHtPKTADSQ	phosphorylation up-regulates	21965652	SIGNOR-176656
DAPK1	MCM3	Ser160 View in OncoXplorer	KTIERRYsDLTTLVA	phosphorylation unknown	18283219	SIGNOR-160958
ATM	MCM3	Ser535 View in OncoXplorer	ATDDPNFsQEDQQDT	phosphorylation unknown	15210935	SIGNOR-126308
CyclinE/CDK2	MCM3	Thr722 View in OncoXplorer	EEMPQVHtPKTADSQ	phosphorylation up-regulates	21965652	SIGNOR-216694

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
CDK2	phosphorylation up-regulates →	MCM3 PThr722	phosphorylation up-regulates →	MCM3	21965652	SIGNOR-176656
DAPK1	phosphorylation up-regulates →	MCM3 PSer160	phosphorylation down-regulates ⊣	MCM3	18283219	SIGNOR-160958
ATM	phosphorylation up-regulates →	MCM3 PSer535	phosphorylation down-regulates ⊣	MCM3	15210935	SIGNOR-126308
CyclinE/CDK2	phosphorylation up-regulates →	MCM3 PThr722	phosphorylation up-regulates →	MCM3	21965652	SIGNOR-216694

Regulator	Mechanism/Effect	Target	SIGNOR-ID
CDK2	phosphorylation → up-regulates	MCM3	SIGNOR-176656
DAPK1	phosphorylation → unknown	MCM3	SIGNOR-160958
ATM	phosphorylation → unknown	MCM3	SIGNOR-126308
CyclinE/CDK2	phosphorylation → up-regulates	MCM3	SIGNOR-216694