Name	MCM3 View Modifications
Full Name	DNA replication licensing factor MCM3
Synonyms	DNA polymerase alpha holoenzyme-associated protein P1, P1-MCM3, RLF subunit beta, p102
Primary ID	P25205
Links	- -
Type	protein
Relations	5
Function	Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.