| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHUK | NFKBIA | Ser36 | RHDSGLDsMKDEEYE | phosphorylation down-regulates quantity by destabilization | 9346241 | SIGNOR-52879 |
| IKK-complex | NFKBIA | Ser36 | RHDSGLDsMKDEEYE | phosphorylation down-regulates quantity by destabilization | 9346241 | SIGNOR-209773 |
| CSNK2A1 | NFKBIA | Ser36 | RHDSGLDsMKDEEYE | phosphorylation down-regulates quantity by destabilization | 10398585 | SIGNOR-249333 |
| IKBKE | NFKBIA | Ser36 | RHDSGLDsMKDEEYE | phosphorylation down-regulates quantity by destabilization | 11815618 | SIGNOR-249367 |
| TBK1 | NFKBIA | Ser36 | RHDSGLDsMKDEEYE | phosphorylation down-regulates quantity by destabilization | 11815618 | SIGNOR-246643 |
| IKK-complex | NFKBIA | Ser36 | RHDSGLDsMKDEEYE | phosphorylation down-regulates | 9346241 | SIGNOR-216389 |
| IKBKB | NFKBIA | Ser36 | RHDSGLDsMKDEEYE | phosphorylation down-regulates quantity by destabilization | 11815618 | SIGNOR-249366 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CHUK | phosphorylation up-regulates → | NFKBIA PSer36 | phosphorylation down-regulates ⊣ | NFKBIA | 9346241 | SIGNOR-52879 |
| IKK-complex | phosphorylation up-regulates → | NFKBIA PSer36 | phosphorylation down-regulates ⊣ | NFKBIA | 9346241 | SIGNOR-209773 |
| CSNK2A1 | phosphorylation up-regulates → | NFKBIA PSer36 | phosphorylation down-regulates ⊣ | NFKBIA | 10398585 | SIGNOR-249333 |
| IKBKE | phosphorylation up-regulates → | NFKBIA PSer36 | phosphorylation down-regulates ⊣ | NFKBIA | 11815618 | SIGNOR-249367 |
| TBK1 | phosphorylation up-regulates → | NFKBIA PSer36 | phosphorylation down-regulates ⊣ | NFKBIA | 11815618 | SIGNOR-246643 |
| IKK-complex | phosphorylation up-regulates → | NFKBIA PSer36 | phosphorylation down-regulates ⊣ | NFKBIA | 9346241 | SIGNOR-216389 |
| IKBKB | phosphorylation up-regulates → | NFKBIA PSer36 | phosphorylation down-regulates ⊣ | NFKBIA | 11815618 | SIGNOR-249366 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CHUK | phosphorylation down-regulates quantity by destabilization | NFKBIA | SIGNOR-52879 |
| IKK-complex | phosphorylation down-regulates quantity by destabilization | NFKBIA | SIGNOR-209773 |
| CSNK2A1 | phosphorylation down-regulates quantity by destabilization | NFKBIA | SIGNOR-249333 |
| IKBKE | phosphorylation down-regulates quantity by destabilization | NFKBIA | SIGNOR-249367 |
| TBK1 | phosphorylation down-regulates quantity by destabilization | NFKBIA | SIGNOR-246643 |
| IKK-complex | phosphorylation down-regulates | NFKBIA | SIGNOR-216389 |
| IKBKB | phosphorylation down-regulates quantity by destabilization | NFKBIA | SIGNOR-249366 |
