Entity Details

Name	DNMT1_Ser143
ID	P26358
Role	residue
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Data Summary

PTM Format

SIGNOR Summary

Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
AKT	DNMT1	Ser143 View in OncoXplorer	RTPRRSKsDGEAKPE	phosphorylation up-regulates	21151116	SIGNOR-244232
AKT1	DNMT1	Ser143 View in OncoXplorer	RTPRRSKsDGEAKPE	phosphorylation up-regulates	21151116	SIGNOR-170530

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
AKT	phosphorylation up-regulates →	DNMT1 PSer143	phosphorylation up-regulates →	DNMT1	21151116	SIGNOR-244232
AKT1	phosphorylation up-regulates →	DNMT1 PSer143	phosphorylation up-regulates →	DNMT1	21151116	SIGNOR-170530

Regulator	Mechanism/Effect	Target	SIGNOR-ID
AKT	phosphorylation → up-regulates	DNMT1	SIGNOR-244232
AKT1	phosphorylation → up-regulates	DNMT1	SIGNOR-170530