| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCE | CHAT | Ser465 | LKHVTQSsRKLIRAD | phosphorylation up-regulates | 15381704 | SIGNOR-129304 |
| PRKCG | CHAT | Ser465 | LKHVTQSsRKLIRAD | phosphorylation up-regulates | 15381704 | SIGNOR-129320 |
| PRKCA | CHAT | Ser465 | LKHVTQSsRKLIRAD | phosphorylation up-regulates | 15381704 | SIGNOR-129264 |
| PRKCB | CHAT | Ser465 | LKHVTQSsRKLIRAD | phosphorylation up-regulates | 15381704 | SIGNOR-129284 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| PRKCE | phosphorylation up-regulates → | CHAT PSer465 | phosphorylation up-regulates → | CHAT | 15381704 | SIGNOR-129304 |
| PRKCG | phosphorylation up-regulates → | CHAT PSer465 | phosphorylation up-regulates → | CHAT | 15381704 | SIGNOR-129320 |
| PRKCA | phosphorylation up-regulates → | CHAT PSer465 | phosphorylation up-regulates → | CHAT | 15381704 | SIGNOR-129264 |
| PRKCB | phosphorylation up-regulates → | CHAT PSer465 | phosphorylation up-regulates → | CHAT | 15381704 | SIGNOR-129284 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| PRKCE | phosphorylation → up-regulates | CHAT | SIGNOR-129304 |
| PRKCG | phosphorylation → up-regulates | CHAT | SIGNOR-129320 |
| PRKCA | phosphorylation → up-regulates | CHAT | SIGNOR-129264 |
| PRKCB | phosphorylation → up-regulates | CHAT | SIGNOR-129284 |
