| Name | LTK |
| ID | P29376 |
| Role | kinase |
| Enzymatic Domains |
Protein kinase 510-786 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LTK | CBL | – | phosphorylation up-regulates | 9223670 | SIGNOR-49528 | |
| LTK | SHC1 | – | phosphorylation up-regulates | 9223670 | SIGNOR-49625 | |
| LTK | IRS1 | – | phosphorylation up-regulates | 9223670 | SIGNOR-49531 | |
| LTK | PREB | Tyr10 | RRRAPELyRAPFPLY | phosphorylation down-regulates activity | 31227593 | SIGNOR-273650 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| LTK | phosphorylation up-regulates → | PREB PTyr10 | phosphorylation down-regulates ⊣ | PREB | 31227593 | SIGNOR-273650 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| LTK | phosphorylation → up-regulates | CBL | SIGNOR-49528 |
| LTK | phosphorylation → up-regulates | SHC1 | SIGNOR-49625 |
| LTK | phosphorylation → up-regulates | IRS1 | SIGNOR-49531 |
| LTK | phosphorylation → down-regulates activity | PREB | SIGNOR-273650 |