Modifier	Substrate	Residue	Sequence	Mechanism/Effect	PMID	Interaction ID
MAPK1	PML	Ser527 View in OncoXplorer	PHLDGPPsPRSPVIG	phosphorylation up-regulates	15093545	SIGNOR-124252

Enzyme	Effect	Phosphosite	Effect	Target	PMID	Interaction ID
MAPK1	phosphorylation up-regulates →	PML PSer527	phosphorylation up-regulates →	PML	15093545	SIGNOR-124252

Regulator	Mechanism/Effect	Target	SIGNOR-ID
MAPK1	phosphorylation → up-regulates	PML	SIGNOR-124252