| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | CDC27 | Ser426 | TQPNINDsLEITKLD | phosphorylation up-regulates | 14657031 | SIGNOR-119873 |
| AMPK | CDC27 | Ser379 | NALPRRSsRLFTSDS | phosphorylation unknown | 22137581 | SIGNOR-216434 |
| CSNK2A1 | CDC27 | Ser154 | FLWSPFEsLCEIGEK | phosphorylation up-regulates | 21209074 | SIGNOR-170872 |
| PRKAA2 | CDC27 | Ser379 | NALPRRSsRLFTSDS | phosphorylation unknown | 22137581 | SIGNOR-195106 |
| CDK1 | CDC27 | Thr446 | EGKISTItPQIQAFN | phosphorylation up-regulates | 14657031 | SIGNOR-119877 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CDK1 | phosphorylation up-regulates → | CDC27 PSer426 | phosphorylation up-regulates → | CDC27 | 14657031 | SIGNOR-119873 |
| AMPK | phosphorylation up-regulates → | CDC27 PSer379 | phosphorylation down-regulates ⊣ | CDC27 | 22137581 | SIGNOR-216434 |
| CSNK2A1 | phosphorylation up-regulates → | CDC27 PSer154 | phosphorylation up-regulates → | CDC27 | 21209074 | SIGNOR-170872 |
| PRKAA2 | phosphorylation up-regulates → | CDC27 PSer379 | phosphorylation down-regulates ⊣ | CDC27 | 22137581 | SIGNOR-195106 |
| CDK1 | phosphorylation up-regulates → | CDC27 PThr446 | phosphorylation up-regulates → | CDC27 | 14657031 | SIGNOR-119877 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CDK1 | phosphorylation → up-regulates | CDC27 | SIGNOR-119873 |
| AMPK | phosphorylation → unknown | CDC27 | SIGNOR-216434 |
| CSNK2A1 | phosphorylation → up-regulates | CDC27 | SIGNOR-170872 |
| PRKAA2 | phosphorylation → unknown | CDC27 | SIGNOR-195106 |
| CDK1 | phosphorylation → up-regulates | CDC27 | SIGNOR-119877 |
