| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | CDC25C | Thr130 | PAQLLCStPNGLDRG | phosphorylation up-regulates | 10864927 | SIGNOR-216769 |
| CDK1 | CDC25C | Thr130 | PAQLLCStPNGLDRG | phosphorylation up-regulates | 10864927 | SIGNOR-78424 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| CyclinB/CDK1 | phosphorylation up-regulates → | CDC25C PThr130 | phosphorylation up-regulates → | CDC25C | 10864927 | SIGNOR-216769 |
| CDK1 | phosphorylation up-regulates → | CDC25C PThr130 | phosphorylation up-regulates → | CDC25C | 10864927 | SIGNOR-78424 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| CyclinB/CDK1 | phosphorylation → up-regulates | CDC25C | SIGNOR-216769 |
| CDK1 | phosphorylation → up-regulates | CDC25C | SIGNOR-78424 |
