Summary

Name CDC25C
Full Name M-phase inducer phosphatase 3
Synonyms Dual specificity phosphatase Cdc25C
Primary ID P30307
Links - -
Type protein
Relations 45
Function Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.

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Modifications Tables

Relations

Regulator Mechanism target score
+ up-regulates img/direct-activation.png phosphorylation CDC25C 0.2
Publications: 5 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation CDC25C 0.37
Publications: 11 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation CDC25C 0.34
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation CDC25C 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation CDC25C 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation CDC25C 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation CDC25C 0.36
Publications: 2 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation CDC25C 0.47
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation CDC25C 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png phosphorylation CDC25C 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation CDC25C 0.14
Publications: 1 Organism: Chlorocebus Aethiops
+ img/unknown.png phosphorylation CDC25C 0.28
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation CDC25C 0.34
Publications: 1 Organism: Homo Sapiens
+ down-regulates activity img/direct_inhibition.png phosphorylation CDC25C 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation CDC25C 0.14
Publications: 1 Organism: Homo Sapiens
Tissue: Brain
+ down-regulates img/direct_inhibition.png phosphorylation CDC25C 0.34
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation CDC25C 0.46
Publications: 1 Organism: Homo Sapiens
+ img/unknown.png phosphorylation CDC25C 0.36
Publications: 1 Organism: In Vitro
+ down-regulates activity img/direct_inhibition.png phosphorylation CDC25C 0.34
Publications: 1 Organism: In Vitro
+ up-regulates activity img/direct-activation.png phosphorylation CDC25C 0.42
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png dephosphorylation CDK1 0.46
Publications: 2 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png dephosphorylation CyclinB/CDK1 0.14
Publications: 2 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png phosphorylation CDC25C 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates img/direct-activation.png binding CDC25C 0.14
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/indirect_inhibition.png CDC25C 0.14
Publications: 1 Organism: Homo Sapiens
+ up-regulates activity img/direct-activation.png phosphorylation CDC25C 0.2
Publications: 1 Organism: Homo Sapiens
+ down-regulates img/direct_inhibition.png relocalization CDC25C 0.14
Publications: 1 Organism: Homo Sapiens