Entity Details

Name SLC6A4
ID P31645
Role substrate
Enzymatic Domains
View in

Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
SRCSLC6A4Tyr47SGQISNGySAVPSPGphosphorylation
up-regulates quantity by stabilization		21992875SIGNOR-276385
PRKG1SLC6A4Thr276SIWKGVKtSGKVVWVphosphorylation
up-regulates		17913921SIGNOR-158186
SRCSLC6A4Tyr142MELALGQyHRNGCISphosphorylation
up-regulates quantity by stabilization		21992875SIGNOR-276386
TBK1SLC6A4Ser13LNSQKQLsACEDGEDphosphorylation
up-regulates activity		32757223SIGNOR-278384
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
SRCphosphorylation
up-regulates
→
SLC6A4
PTyr47		phosphorylation
up-regulates
→		SLC6A421992875SIGNOR-276385
PRKG1phosphorylation
up-regulates
→
SLC6A4
PThr276		phosphorylation
up-regulates
→		SLC6A417913921SIGNOR-158186
SRCphosphorylation
up-regulates
→
SLC6A4
PTyr142		phosphorylation
up-regulates
→		SLC6A421992875SIGNOR-276386
TBK1phosphorylation
up-regulates
→
SLC6A4
PSer13		phosphorylation
up-regulates
→		SLC6A432757223SIGNOR-278384
Regulator Mechanism/Effect Target SIGNOR-ID
SRCphosphorylation
→
up-regulates quantity by stabilization 		SLC6A4SIGNOR-276385
PRKG1phosphorylation
→
up-regulates 		SLC6A4SIGNOR-158186
SRCphosphorylation
→
up-regulates quantity by stabilization 		SLC6A4SIGNOR-276386
TBK1phosphorylation
→
up-regulates activity 		SLC6A4SIGNOR-278384