| Name | AKT1 |
| ID | P31749 |
| Role | kinase |
| Enzymatic Domains |
PH 5-108 PROSITE-ProRule
Protein kinase 150-408 PROSITE-ProRule
AGC-kinase C-terminal 409-480 PROSITE-ProRule |
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| Modifier | Substrate | Residue | Sequence | Mechanism/Effect | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | ACOT4 | Ser392 | GGEPRAHsKAQEDAW | phosphorylation up-regulates quantity by stabilization | 33148467 | SIGNOR-271820 |
| AKT1 | METTL1 | Ser27 | YYRQRAHsNPMADHT | phosphorylation down-regulates | 3627513 | SIGNOR-24994 |
| AKT1 | YBX1 | Ser102 | NPRKYLRsVGDGETV | phosphorylation up-regulates | 19036157 | SIGNOR-252521 |
| AKT1 | CARD11 | Ser652 | LERPFRPsVTSVGHV | phosphorylation up-regulates activity | 24548923 | SIGNOR-276256 |
| AKT1 | RUNX2 | – | phosphorylation down-regulates activity | 23389849 | SIGNOR-280176 | |
| AKT1 | CASP9 | Ser196 | KLRRRFSsLHFMVEV | phosphorylation down-regulates activity | 9812896 | SIGNOR-252581 |
| AKT1 | TERT | Ser824 | AVRIRGKsYVQCQGI | phosphorylation up-regulates | 10224060 | SIGNOR-67317 |
| AKT1 | ESR1 | Ser167 | GGRERLAsTNDKGSM | phosphorylation up-regulates | 11108261 | SIGNOR-84975 |
| AKT1 | FOXO | – | phosphorylation down-regulates activity | 21798082 | SIGNOR-252841 | |
| AKT1 | TSC | – | phosphorylation down-regulates activity | 19593385 | SIGNOR-235340 | |
| AKT1 | EP300 | Ser1834 | MLRRRMAsMQRTGVV | phosphorylation up-regulates | 16926151 | SIGNOR-148983 |
| AKT1 | FOXO3 | Thr32 | QSRPRSCtWPLQRPE | phosphorylation down-regulates activity | 19188143 | SIGNOR-252524 |
| AKT1 | FOXO | Ser315 | DFRSRTNsNASTVSG | phosphorylation down-regulates quantity by destabilization | 19951971 | SIGNOR-252845 |
| AKT1 | FOXO | – | phosphorylation down-regulates | 21798082 | SIGNOR-252843 | |
| AKT1 | CTNNB1 | Ser552 | QDTQRRTsMGGTQQQ | phosphorylation up-regulates | 17287208 | SIGNOR-252499 |
| AKT1 | BLVRA | Ser230 | LKRNRYLsFHFKSGS | phosphorylation up-regulates activity | 15870194 | SIGNOR-275517 |
| AKT1 | RANBP3 | Ser126 | VKRERTSsLTQFPPS | phosphorylation unknown | 18280241 | SIGNOR-252504 |
| AKT1 | PHF20 | Ser291 | ELRRRKIsKGCEVPL | phosphorylation down-regulates | 22334668 | SIGNOR-252529 |
| AKT1 | CELF1 | Ser28 | GQVPRTWsEKDLREL | phosphorylation up-regulates activity | 18570922 | SIGNOR-280173 |
| AKT1 | GAPDH | Thr237 | GMAFRVPtANVSVVD | phosphorylation down-regulates activity | 23332158 | SIGNOR-280174 |
| AKT1 | PRKCD | – | phosphorylation up-regulates activity | 25247763 | SIGNOR-280175 | |
| AKT1 | UPF1 | Thr151 | FCNGRGNtSGSHIVN | phosphorylation up-regulates activity | 35675814 | SIGNOR-277597 |
| AKT1 | DOCK6 | Ser1194 | GQRSRLAsMLDSDTE | phosphorylation up-regulates activity | 23462102 | SIGNOR-275666 |
| AKT1 | FOXO | Ser253 | APRRRAVsMDNSNKY | phosphorylation down-regulates quantity by destabilization | 19951971 | SIGNOR-252844 |
| AKT1 | FBXO31 | Ser33 | AETAAADsEPDTDPE | phosphorylation down-regulates quantity by destabilization | 29343641 | SIGNOR-277376 |
| AKT1 | SIRT6 | Ser338 | PKRERPTsPAPHRPP | phosphorylation down-regulates activity | 25074979 | SIGNOR-278465 |
| AKT1 | MDM2 | Ser166 | SSRRRAIsETEENSD | phosphorylation up-regulates quantity by stabilization | 11504915 | SIGNOR-116270 |
| AKT1 | BAD | Ser75 | EIRSRHSsYPAGTED | phosphorylation down-regulates activity | 9381178 | SIGNOR-252562 |
| AKT1 | SRPK2 | Thr492 | PSHDRSRtVSASSTG | phosphorylation up-regulates | 19592491 | SIGNOR-186760 |
| AKT1 | CABLES1 | Thr309 | APLRRCRtLSGSPRP | phosphorylation down-regulates activity | 25361894 | SIGNOR-276756 |
| AKT1 | GSK3B | Ser9 | SGRPRTTsFAESCKP | phosphorylation down-regulates activity | 9373175 | SIGNOR-252546 |
| AKT1 | ADAR | Thr1033 | RLGERLRtMSCSDKI | phosphorylation down-regulates activity | 31095429 | SIGNOR-276193 |
| AKT1 | FOXO | Thr32 | QSRPRSCtWPLQRPE | phosphorylation down-regulates activity | 19188143 | SIGNOR-252848 |
| AKT1 | PDCD4 | Ser67 | KRRLRKNsSRDSGRG | phosphorylation down-regulates | 17053147 | SIGNOR-252496 |
| AKT1 | BAD | Ser99 | PFRGRSRsAPPNLWA | phosphorylation down-regulates activity | 9381178 | SIGNOR-252563 |
| AKT1 | LARP1 | Ser847 | EHRPRTAsISSSPSE | phosphorylation down-regulates activity | 28650797 | SIGNOR-260991 |
| AKT1 | CDKN1C | Thr310 | GVGSVEQtPRKRLR | phosphorylation down-regulates | 23421998 | SIGNOR-252536 |
| AKT1 | PTK2 | Ser601 | INFRRFTsASDVWMF | phosphorylation up-regulates activity | 31138602 | SIGNOR-279775 |
| AKT1 | PTK2 | Ser695 | EERMRMEsRRQATVS | phosphorylation up-regulates activity | 31138602 | SIGNOR-279776 |
| AKT1 | HSF1 | Ser230 | PKYSRQFsLEHVHGS | phosphorylation up-regulates activity | 35080342 | SIGNOR-278373 |
| AKT1 | MDM2 | Ser186 | RQRKRHKsDSISLSF | phosphorylation up-regulates activity | 11504915 | SIGNOR-116274 |
| AKT1 | MAP3K11 | Ser674 | PGRERGEsPTTPPTP | phosphorylation down-regulates | 12458207 | SIGNOR-252592 |
| AKT1 | SH2B2 | Ser598 | SARSRSNsAERLLEA | phosphorylation up-regulates activity | 16141217 | SIGNOR-252557 |
| AKT1 | EZH2 | Ser21 | CWRKRVKsEYMRLRQ | phosphorylation down-regulates activity | 16224021 | SIGNOR-141043 |
| AKT1 | BECN1 | Ser295 | FRLGRLPsVPVEWNE | phosphorylation down-regulates activity | 31852899 | SIGNOR-279667 |
| AKT1 | HSF1 | Ser326 | SSVDTLLsPTALIDS | phosphorylation up-regulates activity | 35080342 | SIGNOR-277581 |
| AKT1 | RARG | Ser371 | YARRRRPsQPYMFPR | phosphorylation up-regulates activity | 31740618 | SIGNOR-277492 |
| AKT1 | FOXO3 | Ser253 | APRRRAVsMDNSNKY | phosphorylation down-regulates quantity by destabilization | 19951971 | SIGNOR-249626 |
| AKT1 | HSF1 | Thr527 | PPKAKDPtVS | phosphorylation up-regulates activity | 35080342 | SIGNOR-277578 |
| AKT1 | MAPK1 | – | phosphorylation up-regulates activity | 20693286 | SIGNOR-279136 | |
| AKT1 | PDK1 | Thr346 | APRPRVEtSRAVPLA | phosphorylation up-regulates activity | 27505672 | SIGNOR-277272 |
| AKT1 | ADRB2 | Ser345 | ELLCLRRsSLKAYGN | phosphorylation down-regulates | 11809767 | SIGNOR-252469 |
| AKT1 | CREB1 | Ser119 | EILSRRPsYRKILND | phosphorylation up-regulates activity | 9829964 | SIGNOR-252549 |
| AKT1 | ARFIP2 | Ser260 | GTRGRLEsAQATFQA | phosphorylation unknown | 15809304 | SIGNOR-252476 |
| AKT1 | TWIST1 | Ser42 | GGRKRRSsRRSAGGG | phosphorylation up-regulates | 20400976 | SIGNOR-164884 |
| AKT1 | FOXO | – | phosphorylation down-regulates | 18394876 | SIGNOR-252859 | |
| AKT1 | NCF1 | Ser328 | QDAYRRNsVRFLQQR | phosphorylation up-regulates | 10559253 | SIGNOR-252587 |
| AKT1 | HTRA2 | Ser212 | RVRVRLLsGDTYEAV | phosphorylation down-regulates | 17311912 | SIGNOR-252500 |
| AKT1 | GSK3A | Ser21 | SGRARTSsFAEPGGG | phosphorylation down-regulates | 11035810 | SIGNOR-252589 |
| AKT1 | CDCA7 | Thr163 | SRRPRRRtFPGVASR | phosphorylation down-regulates | 23166294 | SIGNOR-252533 |
| AKT1 | YAP1 | Ser127 | PQHVRAHsSPASLQL | phosphorylation down-regulates | 12535517 | SIGNOR-252593 |
| AKT1 | PFKFB2 | Ser483 | IRRPRNYsVGSRPLK | phosphorylation unknown | 12853467 | SIGNOR-252575 |
| AKT1 | PALLD | Ser1118 | VRRPRSRsRDSGDEN | phosphorylation unknown | 20471940 | SIGNOR-252510 |
| AKT1 | VCP | Ser746 | AMRFARRsVSDNDIR | phosphorylation up-regulates | 16551632 | SIGNOR-252492 |
| AKT1 | FOXO | – | phosphorylation down-regulates quantity by destabilization | 21440011 | SIGNOR-252858 | |
| AKT1 | FOXO | Thr24 | LPRPRSCtWPLPRPE | phosphorylation down-regulates | 10377430 | SIGNOR-252857 |
| AKT1 | HSF1 | Thr142 | DSVTKLLtDVQLMKG | phosphorylation up-regulates activity | 35080342 | SIGNOR-277579 |
| AKT1 | TARBP2 | Ser283 | ILSLRSCsLGSLGAL | phosphorylation up-regulates activity | 27407113 | SIGNOR-274064 |
| AKT1 | FOXO3 | Ser253 | APRRRAVsMDNSNKY | phosphorylation down-regulates activity | 19188143 | SIGNOR-252522 |
| AKT1 | RPS6KA3 | Ser19 | KMAVESPsDSAENGQ | phosphorylation down-regulates activity | 33574926 | SIGNOR-277548 |
| AKT1 | PEA15 | Ser116 | KDIIRQPsEEEIIKL | phosphorylation up-regulates activity | 12808093 | SIGNOR-102092 |
| AKT1 | PFKFB2 | Ser483 | IRRPRNYsVGSRPLK | phosphorylation up-regulates activity | 23457334 | SIGNOR-252528 |
| AKT1 | S1PR1 | Thr236 | RTRSRRLtFRKNISK | phosphorylation up-regulates activity | 11583630 | SIGNOR-252467 |
| AKT1 | MST1R | Ser1394 | VRRPRPLsEPPRPT | phosphorylation up-regulates | 14505491 | SIGNOR-252471 |
| AKT1 | FOXO6 | – | phosphorylation down-regulates | 18394876 | SIGNOR-252582 | |
| AKT1 | TSC2 | Ser939 | SFRARSTsLNERPKS | phosphorylation down-regulates activity | 12150915 | SIGNOR-235511 |
| AKT1 | CTBP1 | – | phosphorylation down-regulates quantity | 20361981 | SIGNOR-278304 | |
| AKT1 | STK4 | Thr387 | TMKRRDEtMQPAKPS | phosphorylation down-regulates | 23431053 | SIGNOR-252537 |
| AKT1 | PFKFB2 | Ser466 | PVRMRRNsFTPLSSS | phosphorylation unknown | 12853467 | SIGNOR-252574 |
| AKT1 | LONP1 | Ser173 | VFLKRDDsNESDVVE | phosphorylation up-regulates activity | 31406245 | SIGNOR-265724 |
| AKT1 | BMI1 | Ser316 | ANRPRKSsVNGSSAT | phosphorylation up-regulates activity | 22505453 | SIGNOR-252559 |
| AKT1 | STK4 | Thr120 | IIRLRNKtLTEDEIA | phosphorylation down-regulates | 19940129 | SIGNOR-252507 |
| AKT1 | DLX5 | – | phosphorylation up-regulates | 22298955 | SIGNOR-195546 | |
| AKT1 | BRCA1 | Ser694 | QTSKRHDsDTFPELK | phosphorylation up-regulates | 20085797 | SIGNOR-163472 |
| AKT1 | FOXO3 | Ser315 | DFRSRTNsNASTVSG | phosphorylation down-regulates activity | 19188143 | SIGNOR-252523 |
| AKT1 | PDE3B | Ser318 | CKIFRRPsLPCISRE | phosphorylation up-regulates activity | 10454575 | SIGNOR-252554 |
| AKT1 | DNMT1 | Ser143 | RTPRRSKsDGEAKPE | phosphorylation up-regulates | 21151116 | SIGNOR-170530 |
| AKT1 | CARD11 | Ser558 | MQPPRSRsSIMSITA | phosphorylation up-regulates activity | 24548923 | SIGNOR-276254 |
| AKT1 | ESR1 | Ser118 | LHPPPQLsPFLQPHG | phosphorylation up-regulates | 11108261 | SIGNOR-84971 |
| AKT1 | FOXO | Ser256 | SPRRRAAsMDNNSKF | phosphorylation down-regulates | 10377430 | SIGNOR-252856 |
| AKT1 | PLN | Thr17 | SAIRRAStIEMPQQA | phosphorylation down-regulates activity | 19696029 | SIGNOR-252578 |
| AKT1 | CLK2 | Ser34 | HKRRRSRsWSSSSDR | phosphorylation up-regulates | 20682768 | SIGNOR-167336 |
| AKT1 | FOXO | Ser262 | TFRPRSSsNASSVST | phosphorylation down-regulates activity | 10217147 | SIGNOR-252862 |
| AKT1 | BCL2L11 | Ser87 | FIFMRRSsLLSRSSS | phosphorylation down-regulates activity | 16282323 | SIGNOR-252487 |
| AKT1 | FOXO | Ser315 | DFRSRTNsNASTVSG | phosphorylation down-regulates activity | 19188143 | SIGNOR-252850 |
| AKT1 | TMIGD2 | Ser220 | GKDQRGQsIYSTSFP | phosphorylation up-regulates activity | 31341021 | SIGNOR-273481 |
| AKT1 | HSF1 | Thr527 | PPKAKDPtVS | phosphorylation up-regulates activity | 35080342 | SIGNOR-278371 |
| AKT1 | GATA1 | Ser310 | QTRNRKAsGKGKKKR | phosphorylation up-regulates | 16107690 | SIGNOR-139782 |
| AKT1 | ESR1 | Ser106 | PLNSVSPsPLMLLHP | phosphorylation up-regulates | 11108261 | SIGNOR-84967 |
| AKT1 | MAPKAP1 | Thr86 | GIRRRSNtAQRLERL | phosphorylation up-regulates activity | 26235620 | SIGNOR-276932 |
| AKT1 | SKI | Thr458 | QPRKRKLtVDTPGAP | phosphorylation down-regulates | 19875456 | SIGNOR-252527 |
| AKT1 | NIBAN1 | Ser602 | ASPARRAsAILPGVL | phosphorylation unknown | 22510990 | SIGNOR-252530 |
| AKT1 | KDM5A | Thr285 | QMRQRKGtLSVNFVD | phosphorylation up-regulates activity | 27292631 | SIGNOR-274061 |
| AKT1 | MAP3K5 | Ser83 | ATRGRGSsVGGGSRR | phosphorylation down-regulates activity | 11154276 | SIGNOR-252465 |
| AKT1 | Hexokinase | – | phosphorylation up-regulates activity | 31435020 | SIGNOR-270267 | |
| AKT1 | TAL1 | Thr90 | EARHRVPtTELCRPP | phosphorylation down-regulates | 15930267 | SIGNOR-252479 |
| AKT1 | MAP3K8 | Ser413 | LERKRLLsRKELELP | phosphorylation up-regulates activity | 12138205 | SIGNOR-252572 |
| AKT1 | AR | Ser792 | CVRMRHLsQEFGWLQ | phosphorylation down-regulates activity | 11404460 | SIGNOR-108508 |
| AKT1 | WNK1 | Thr60 | EYRRRRHtMDKDSRG | phosphorylation up-regulates | 16081417 | SIGNOR-252481 |
| AKT1 | PARK7 | Thr125 | GFGSKVTtHPLAKDK | phosphorylation up-regulates activity | 32858971 | SIGNOR-275582 |
| AKT1 | PTK2 | Thr700 | MESRRQAtVSWDSGG | phosphorylation up-regulates activity | 31138602 | SIGNOR-279777 |
| AKT1 | SMURF1 | Thr145 | QTRDRIGtGGSVVDC | phosphorylation up-regulates activity | 27036023 | SIGNOR-279778 |
| AKT1 | EPHA2 | Ser897 | RVSIRLPsTSGSEGV | phosphorylation up-regulates activity | 35869144 | SIGNOR-279787 |
| AKT1 | FOXO1 | Ser256 | SPRRRAAsMDNNSKF | phosphorylation down-regulates activity | 10377430 | SIGNOR-236159 |
| AKT1 | RAB3IP | Ser165 | LSRLRSPsVLEVREK | phosphorylation up-regulates activity | 36797475 | SIGNOR-277802 |
| AKT1 | LARP6 | Ser451 | QEKSPGTsPLLSRKM | phosphorylation up-regulates activity | 26932461 | SIGNOR-277213 |
| AKT1 | CFLAR | Ser273 | LLRDTFTsLGYEVQK | phosphorylation down-regulates quantity | 19339247 | SIGNOR-252548 |
| AKT1 | ADARB1 | Thr553 | LQGERLLtMSCSDKI | phosphorylation down-regulates activity | 31095429 | SIGNOR-276194 |
| AKT1 | CLK2 | Thr127 | RRRRRSRtFSRSSSQ | phosphorylation up-regulates | 20682768 | SIGNOR-167340 |
| AKT1 | RNF11 | Thr135 | DWLMRSFtCPSCMEP | phosphorylation down-regulates quantity | 16123141 | SIGNOR-252558 |
| AKT1 | RAF1 | Ser259 | SQRQRSTsTPNVHMV | phosphorylation down-regulates | 16854453 | SIGNOR-147963 |
| AKT1 | FOXO | Ser197 | APRRRAAsMDSSSKL | phosphorylation down-regulates | 16272144 | SIGNOR-252853 |
| AKT1 | PTK2 | Ser517 | FLQVRKYsLDLASLI | phosphorylation up-regulates activity | 31138602 | SIGNOR-279774 |
| AKT1 | PFKP | – | phosphorylation up-regulates quantity | 29038421 | SIGNOR-279788 | |
| AKT1 | PFKFB3 | Ser461 | NPLMRRNsVTPLASP | phosphorylation up-regulates | 15896703 | SIGNOR-252477 |
| AKT1 | FOXO | Thr32 | QSRPRSCtWPLQRPE | phosphorylation down-regulates quantity by destabilization | 19951971 | SIGNOR-252846 |
| AKT1 | PAWR | – | phosphorylation down-regulates activity | 21555373 | SIGNOR-279668 | |
| AKT1 | SH3RF1 | Ser304 | KNTKKRHsFTSLTMA | phosphorylation down-regulates | 17535800 | SIGNOR-252501 |
| AKT1 | FANCA | Ser1149 | CLRSRDPsLMVDFIL | phosphorylation unknown | 11855836 | SIGNOR-252567 |
| AKT1 | AKT1 | Thr72 | TERPRPNtFIIRCLQ | phosphorylation up-regulates activity | 16549426 | SIGNOR-276054 |
| AKT1 | MDM4 | Ser367 | PDCRRTIsAPVVRPK | phosphorylation up-regulates quantity by stabilization | 18356162 | SIGNOR-252517 |
| AKT1 | ALYREF | Thr219 | GGGTRRGtRGGARGR | phosphorylation up-regulates | 18562279 | SIGNOR-252518 |
| AKT1 | STK3 | Thr384 | GTMKRNAtSPQVQRP | phosphorylation down-regulates | 20086174 | SIGNOR-163537 |
| AKT1 | FOXO | – | phosphorylation down-regulates | 21620960 | SIGNOR-252847 | |
| AKT1 | FOXO3 | Thr32 | QSRPRSCtWPLQRPE | phosphorylation down-regulates quantity by destabilization | 19951971 | SIGNOR-249625 |
| AKT1 | CBY1 | Ser20 | TPPRKSAsLSNLHSL | phosphorylation up-regulates activity | 18573912 | SIGNOR-279002 |
| AKT1 | CABLES1 | Thr415 | AFGARRNtIDSTSSF | phosphorylation down-regulates activity | 25361894 | SIGNOR-276757 |
| AKT1 | USP14 | Ser432 | THQGRSSsSGHYVSW | phosphorylation up-regulates activity | 26523394 | SIGNOR-265056 |
| AKT1 | PIKFYVE | Ser307 | PARNRSAsITNLSLD | phosphorylation up-regulates | 15546921 | SIGNOR-252474 |
| AKT1 | H3-3A | Ser11 | TKQTARKsTGGKAPR | phosphorylation down-regulates activity | 12588998 | SIGNOR-98285 |
| AKT1 | GATA2 | Ser401 | QTRNRKMsNKSKKSK | phosphorylation down-regulates | 15837948 | SIGNOR-135614 |
| AKT1 | FOXO4 | – | phosphorylation down-regulates | 21798082 | SIGNOR-175291 | |
| AKT1 | CHEK1 | Ser280 | AKRPRVTsGGVSESP | phosphorylation down-regulates | 15107605 | SIGNOR-124365 |
| AKT1 | FOXO4 | Ser262 | TFRPRSSsNASSVST | phosphorylation down-regulates activity | 10217147 | SIGNOR-252569 |
| AKT1 | FOXO4 | – | phosphorylation down-regulates | 21620960 | SIGNOR-252515 | |
| AKT1 | SOX2 | Thr118 | RPRRKTKtLMKKDKY | phosphorylation up-regulates quantity by stabilization | 25042802 | SIGNOR-279003 |
| AKT1 | FOXO4 | Thr32 | QSRPRSCtWPLPRPE | phosphorylation down-regulates | 16272144 | SIGNOR-252486 |
| AKT1 | TERT | Ser227 | GARRRGGsASRSLPL | phosphorylation up-regulates | 10224060 | SIGNOR-67313 |
| AKT1 | ADRB2 | Ser346 | LLCLRRSsLKAYGNG | phosphorylation down-regulates | 11809767 | SIGNOR-252470 |
| AKT1 | HK2 | Thr473 | QHRARQKtLEHLQLS | phosphorylation up-regulates activity | 31435020 | SIGNOR-259984 |
| AKT1 | ITGB3 | Thr779 | LYKEATStFTNITYR | phosphorylation down-regulates activity | 10896934 | SIGNOR-252552 |
| AKT1 | POU5F1 | Thr235 | QARKRKRtSIENRVR | phosphorylation up-regulates quantity by stabilization | 23041284 | SIGNOR-252545 |
| AKT1 | ZRANB1 | Thr117 | QRRTRSPtESPQSSG | phosphorylation up-regulates activity | 29748601 | SIGNOR-273484 |
| AKT1 | IMPDH2 | – | phosphorylation up-regulates activity | 10930578 | SIGNOR-261262 | |
| AKT1 | TSC | – | phosphorylation down-regulates activity | 12150915 | SIGNOR-235628 | |
| AKT1 | MAP3K8 | Ser400 | EDQPRCQsLDSALLE | phosphorylation up-regulates activity | 12138205 | SIGNOR-252571 |
| AKT1 | AKT1 | Ser246 | LSRERVFsEDRARFY | phosphorylation up-regulates activity | 16549426 | SIGNOR-276055 |
| AKT1 | VCP | Ser352 | AATNRPNsIDPALRR | phosphorylation up-regulates | 16551632 | SIGNOR-252491 |
| AKT1 | CDKN1B | Thr198 | PGLRRRQt | phosphorylation down-regulates | 12042314 | SIGNOR-88294 |
| AKT1 | CHUK | Thr23 | EMRERLGtGGFGNVC | phosphorylation up-regulates | 19609947 | SIGNOR-187006 |
| AKT1 | CDKN1B | – | phosphorylation down-regulates | 14967450 | SIGNOR-121944 | |
| AKT1 | CARD11 | Ser644 | NLMFRKFsLERPFRP | phosphorylation up-regulates activity | 24548923 | SIGNOR-276255 |
| AKT1 | FOXO1 | Ser319 | TFRPRTSsNASTISG | phosphorylation down-regulates | 11237865 | SIGNOR-105459 |
| AKT1 | PDCD4 | Ser67 | KRRLRKNsSRDSGRG | phosphorylation down-regulates | 18296647 | SIGNOR-252505 |
| AKT1 | TSC2 | Thr1462 | GLRPRGYtISDSAPS | phosphorylation down-regulates activity | 12150915 | SIGNOR-235515 |
| AKT1 | CARHSP1 | Ser52 | TRRTRTFsATVRASQ | phosphorylation unknown | 15910284 | SIGNOR-252478 |
| AKT1 | RAF1 | Ser259 | SQRQRSTsTPNVHMV | phosphorylation down-regulates | 10576741 | SIGNOR-252588 |
| AKT1 | STK3 | Thr117 | IIRLRNKtLIEDEIA | phosphorylation down-regulates | 20086174 | SIGNOR-163533 |
| AKT1 | CDKN1C | Ser282 | FFAKRKRsAPEKSSG | phosphorylation down-regulates | 23421998 | SIGNOR-252535 |
| AKT1 | CASP9 | Ser196 | KLRRRFSsLHFMVEV | phosphorylation down-regulates activity | 10529400 | SIGNOR-252585 |
| AKT1 | TTC3 | Ser378 | AYTPRSLsAPIFTTS | phosphorylation up-regulates | 20059950 | SIGNOR-252508 |
| AKT1 | PIK3R6 | Thr607 | SHRPREVtVSLRATG | phosphorylation up-regulates activity | 25753393 | SIGNOR-275722 |
| AKT1 | BRAF | Ser429 | PQRERKSsSSSEDRN | phosphorylation down-regulates activity | 10869359 | SIGNOR-251472 |
| AKT1 | XIAP | Ser87 | VGRHRKVsPNCRFIN | phosphorylation up-regulates quantity by stabilization | 14645242 | SIGNOR-119488 |
| AKT1 | KDM5A | Ser225 | TRRVKTQsESGDVSR | phosphorylation up-regulates activity | 27292631 | SIGNOR-274060 |
| AKT1 | ZYX | Ser142 | PQPREKVsSIDLEID | phosphorylation down-regulates | 17572661 | SIGNOR-156122 |
| AKT1 | PTK2 | Thr700 | MESRRQAtVSWDSGG | phosphorylation up-regulates activity | 23264741 | SIGNOR-276436 |
| AKT1 | BTK | Thr495 | EMRHRFQtQQLLEMC | phosphorylation down-regulates quantity by destabilization | 23754751 | SIGNOR-276465 |
| AKT1 | LONP1 | Ser181 | NESDVVEsLDEIYHT | phosphorylation up-regulates activity | 31406245 | SIGNOR-265725 |
| AKT1 | USP4 | Ser445 | NHRLRNDsVIVDTFH | phosphorylation up-regulates quantity by stabilization | 22706160 | SIGNOR-273482 |
| AKT1 | TBC1D4 | – | phosphorylation down-regulates | 12637568 | SIGNOR-252594 | |
| AKT1 | BCL3 | Ser41 | KRPLRAPsPEPAAPR | phosphorylation up-regulates quantity by stabilization | 28689659 | SIGNOR-277358 |
| AKT1 | LARP1 | Ser1056 | EGRKRCPsQSSSRPA | phosphorylation down-regulates activity | 28650797 | SIGNOR-260992 |
| AKT1 | FOXO4 | Ser197 | APRRRAAsMDSSSKL | phosphorylation down-regulates activity | 10217147 | SIGNOR-252568 |
| AKT1 | RAC1 | Ser71 | YDRLRPLsYPQTDVF | phosphorylation down-regulates activity | 10617634 | SIGNOR-252576 |
| AKT1 | HMOX1 | Ser188 | LYRSRMNsLEMTPAV | phosphorylation unknown | 15581622 | SIGNOR-252506 |
| AKT1 | NOS3 | Ser1177 | TSRIRTQsFSLQERQ | phosphorylation up-regulates | 11729179 | SIGNOR-112363 |
| AKT1 | DLX5 | – | phosphorylation up-regulates | 21619873 | SIGNOR-252513 | |
| AKT1 | HSF1 | Thr142 | DSVTKLLtDVQLMKG | phosphorylation up-regulates activity | 35080342 | SIGNOR-278372 |
| AKT1 | BAX | Ser184 | VAGVLTAsLTIWKKM | phosphorylation down-regulates activity | 14766748 | SIGNOR-252538 |
| AKT1 | ATG4B | Ser34 | WILGRKYsIFTEKDE | phosphorylation up-regulates activity | 29165041 | SIGNOR-275834 |
| AKT1 | RPS3 | Thr70 | GRRIRELtAVVQKRF | phosphorylation up-regulates activity | 20605787 | SIGNOR-259815 |
| AKT1 | STK3/4 | – | phosphorylation down-regulates | 20086174 | SIGNOR-269945 | |
| AKT1 | SP7 | – | phosphorylation up-regulates | 21619873 | SIGNOR-252514 | |
| AKT1 | FOXO1 | – | phosphorylation down-regulates activity | 18423396 | SIGNOR-236206 | |
| AKT1 | FOXO1 | Thr24 | LPRPRSCtWPLPRPE | phosphorylation down-regulates activity | 10377430 | SIGNOR-236163 |
| AKT1 | MDM2 | Ser188 | RKRHKSDsISLSFDE | phosphorylation up-regulates | 15169778 | SIGNOR-124953 |
| AKT1 | BRCA1 | Thr509 | LKRKRRPtSGLHPED | phosphorylation up-regulates | 17428466 | SIGNOR-154312 |
| AKT1 | HSF1 | Ser326 | SSVDTLLsPTALIDS | phosphorylation up-regulates activity | 35080342 | SIGNOR-278374 |
| AKT1 | NOS3 | Ser615 | SYKIRFNsISCSDPL | phosphorylation up-regulates activity | 24379783 | SIGNOR-251622 |
| AKT1 | PFKFB2 | Ser466 | PVRMRRNsFTPLSSS | phosphorylation up-regulates activity | 10521487 | SIGNOR-252584 |
| AKT1 | FOXO6 | – | phosphorylation down-regulates | 21798082 | SIGNOR-175294 | |
| AKT1 | PRKAA1 | – | phosphorylation down-regulates activity | 16340011 | SIGNOR-252739 | |
| AKT1 | HTT | Ser419 | GGRSRSGsIVELIAG | phosphorylation unknown | 12062094 | SIGNOR-252590 |
| AKT1 | CARD11 | Ser644 | NLMFRKFsLERPFRP | phosphorylation up-regulates activity | 24548923 | SIGNOR-276621 |
| AKT1 | RARA | Ser96 | FVCQDKSsGYHYGVS | phosphorylation down-regulates | 16417524 | SIGNOR-252489 |
| AKT1 | BECN1 | Ser234 | AQYQREYsEFKRQQL | phosphorylation down-regulates activity | 31852899 | SIGNOR-279666 |
| AKT1 | UBE2S | Thr152 | AARARLLtEIHGGAG | phosphorylation up-regulates quantity by stabilization | 27593939 | SIGNOR-265078 |
| AKT1 | ZRANB1 | Ser78 | SARPRVKsSYSMENA | phosphorylation up-regulates activity | 29748601 | SIGNOR-273483 |
| AKT1 | HSF1 | Ser230 | PKYSRQFsLEHVHGS | phosphorylation up-regulates activity | 35080342 | SIGNOR-277580 |
| AKT1 | AGAP2 | Ser985 | THLSRVRsLDLDDWP | phosphorylation up-regulates | 19176382 | SIGNOR-183543 |
| AKT1 | FOXO4 | Ser197 | APRRRAAsMDSSSKL | phosphorylation down-regulates | 16272144 | SIGNOR-252484 |
| AKT1 | FOXO | Ser319 | TFRPRTSsNASTISG | phosphorylation down-regulates | 11237865 | SIGNOR-252860 |
| AKT1 | AR | Ser215 | SGRAREAsGAPTSSK | phosphorylation down-regulates | 17470458 | SIGNOR-154631 |
| AKT1 | SOX2 | Thr116 | KYRPRRKtKTLMKKD | phosphorylation up-regulates quantity by stabilization | 30894683 | SIGNOR-277445 |
| AKT1 | Histone H3 | – | phosphorylation unknown | 12588998 | SIGNOR-265320 | |
| AKT1 | FOXO | Ser253 | APRRRAVsMDNSNKY | phosphorylation down-regulates activity | 19188143 | SIGNOR-252849 |
| AKT1 | NQO1 | Thr128 | FIGEFAYtYAAMYDK | phosphorylation down-regulates quantity by destabilization | 31358653 | SIGNOR-276869 |
| AKT1 | BAD | Ser99 | PFRGRSRsAPPNLWA | phosphorylation down-regulates activity | 9346240 | SIGNOR-52863 |
| AKT1 | SYTL1 | Ser241 | RMLSSSSsVSSLNSS | phosphorylation down-regulates quantity | 15998322 | SIGNOR-273540 |
| AKT1 | DAB2IP | Ser971 | STRLRQQsSSSKGDS | phosphorylation down-regulates activity | 27858941 | SIGNOR-254780 |
| AKT1 | FBXW7 | Ser227 | QQRRRITsVQPPTGL | phosphorylation up-regulates activity | 21620836 | SIGNOR-276328 |
| AKT1 | NCF1 | Ser304 | GAPPRRSsIRNAHSI | phosphorylation up-regulates | 10559253 | SIGNOR-252586 |
| AKT1 | CCDC88A | Ser1417 | INRERQKsLTLTPTR | phosphorylation unknown | 16139227 | SIGNOR-252482 |
| AKT1 | MDM2 | Ser166 | SSRRRAIsETEENSD | phosphorylation up-regulates quantity by stabilization | 15169778 | SIGNOR-124949 |
| AKT1 | AR | Ser215 | SGRAREAsGAPTSSK | phosphorylation down-regulates activity | 11404460 | SIGNOR-108504 |
| AKT1 | FOXO | – | phosphorylation down-regulates activity | 18423396 | SIGNOR-252851 | |
| AKT1 | CDKN1A | Thr145 | QGRKRRQtSMTDFYH | phosphorylation up-regulates quantity by stabilization | 16982699 | SIGNOR-149698 |
| AKT1 | DLC1 | Ser766 | VTRTRSLsACNKRVG | phosphorylation unknown | 16338927 | SIGNOR-252550 |
| AKT1 | KDM5A | Ser287 | RQRKGTLsVNFVDLY | phosphorylation up-regulates activity | 27292631 | SIGNOR-274062 |
| AKT1 | IRAK1 | Thr100 | LRARDIItAWHPPAP | phosphorylation down-regulates activity | 11976320 | SIGNOR-252551 |
| AKT1 | ILF3 | Ser647 | RGRGRGGsIRGRGRG | phosphorylation up-regulates activity | 20870937 | SIGNOR-252512 |
| AKT1 | FOXO | Thr32 | QSRPRSCtWPLPRPE | phosphorylation down-regulates | 16272144 | SIGNOR-252855 |
| AKT1 | PTPN1 | Ser50 | RNRYRDVsPFDHSRI | phosphorylation down-regulates activity | 11579209 | SIGNOR-252542 |
| AKT1 | CDK2 | Thr39 | LKKIRLDtETEGVPS | phosphorylation up-regulates | 18354084 | SIGNOR-178058 |
| AKT1 | MTOR | Ser2448 | RSRTRTDsYSAGQSV | phosphorylation unknown | 10910062 | SIGNOR-251099 |
| AKT1 | GAB2 | Ser159 | LLRERKSsAPSHSSQ | phosphorylation down-regulates | 11782427 | SIGNOR-252468 |
| AKT1 | FOXO4 | Ser262 | TFRPRSSsNASSVST | phosphorylation down-regulates | 16272144 | SIGNOR-252485 |
| AKT1 | IKK-complex | – | phosphorylation up-regulates | 19609947 | SIGNOR-217460 | |
| AKT1 | BAD | Ser118 | GRELRRMsDEFVDSF | phosphorylation down-regulates activity | 9346240 | SIGNOR-52859 |
| AKT1 | PDE3B | Ser295 | VIRPRRRsSCVSLGE | phosphorylation up-regulates activity | 10454575 | SIGNOR-252573 |
| AKT1 | PRKAA1 | Ser496 | ATPQRSGsVSNYRSC | phosphorylation down-regulates activity | 27784766 | SIGNOR-276461 |
| AKT1 | mTORC1 | – | phosphorylation up-regulates activity | 20138985 | SIGNOR-252539 | |
| AKT1 | HIRA | – | phosphorylation up-regulates activity | 27515126 | SIGNOR-279584 | |
| AKT1 | RAB3IP | Ser165 | LSRLRSPsVLEVREK | phosphorylation up-regulates activity | 36797475 | SIGNOR-277816 |
| AKT1 | TIFA | Thr9 | TSFEDADtEETVTCL | phosphorylation up-regulates activity | 27965388 | SIGNOR-273542 |
| AKT1 | KDM5A | Ser1255 | CLTERAMsWQDRARQ | phosphorylation up-regulates activity | 27292631 | SIGNOR-274059 |
| AKT1 | PPARGC1A | Ser571 | RMRSRSRsFSRHRSC | phosphorylation down-regulates activity | 17554339 | SIGNOR-252502 |
| AKT1 | NHEJ1 | Thr181 | LIRDRLKtEPFEENS | phosphorylation down-regulates quantity by destabilization | 25661488 | SIGNOR-276881 |
| AKT1 | EP300 | – | phosphorylation up-regulates | 17964260 | SIGNOR-158624 | |
| AKT1 | EIF4B | Ser422 | RERSRTGsESSQTGT | phosphorylation up-regulates | 18836482 | SIGNOR-252520 |
| AKT1 | CDKN1B | Thr157 | GIRKRPAtDDSSTQN | phosphorylation down-regulates | 18570873 | SIGNOR-179109 |
| AKT1 | FOXO1 | – | phosphorylation down-regulates quantity by destabilization | 21440011 | SIGNOR-209647 | |
| AKT1 | SCYL1 | Thr469 | STRHRVLtSAFSRAT | phosphorylation up-regulates activity | 24769208 | SIGNOR-265496 |
| AKT1 | PFKFB2 | Ser466 | PVRMRRNsFTPLSSS | phosphorylation up-regulates activity | 12853467 | SIGNOR-252555 |
| AKT1 | COPS6 | Ser60 | DHWIRMRsQEGRPVQ | phosphorylation up-regulates | 23095642 | SIGNOR-252532 |
| AKT1 | KHSRP | Ser193 | GLPERSVsLTGAPES | phosphorylation down-regulates activity | 17177604 | SIGNOR-252497 |
| AKT1 | VIM | Ser39 | TTSTRTYsLGSALRP | phosphorylation up-regulates quantity by stabilization | 20856200 | SIGNOR-252511 |
| AKT1 | PFKFB2 | Ser483 | IRRPRNYsVGSRPLK | phosphorylation up-regulates activity | 12853467 | SIGNOR-252464 |
| AKT1 | RAF1 | – | phosphorylation down-regulates | 22798428 | SIGNOR-252531 | |
| AKT1 | TENT2 | Ser116 | LSGERRYsMPPLFHT | phosphorylation down-regulates activity | 31057087 | SIGNOR-259405 |
| AKT1 | VCP | Ser748 | RFARRSVsDNDIRKY | phosphorylation up-regulates | 16551632 | SIGNOR-252493 |
| AKT1 | BTK | Ser51 | FERGRRGsKKGSIDV | phosphorylation down-regulates quantity by destabilization | 23754751 | SIGNOR-276466 |
| AKT1 | YWHAZ | Ser58 | VVGARRSsWRVVSSI | phosphorylation unknown | 11956222 | SIGNOR-116587 |
| AKT1 | HNRNPA1 | Ser199 | SQRGRSGsGNFGGGR | phosphorylation down-regulates | 18562319 | SIGNOR-252519 |
| AKT1 | HSPB1 | Ser82 | RALSRQLsSGVSEIR | phosphorylation down-regulates | 19593530 | SIGNOR-252526 |
| AKT1 | P300/PCAF | – | phosphorylation up-regulates | 17964260 | SIGNOR-217670 | |
| AKT1 | ATXN1 | Ser775 | ATRKRRWsAPESRKL | phosphorylation up-regulates quantity by stabilization | 12757707 | SIGNOR-252561 |
| AKT1 | PDCD4 | Ser457 | RGRKRFVsEGDGGRL | phosphorylation down-regulates | 16357133 | SIGNOR-252488 |
| AKT1 | TP53RK | Ser250 | RLRGRKRsMVG | phosphorylation up-regulates | 17712528 | SIGNOR-252503 |
| AKT1 | STK3 | Thr117 | IIRLRNKtLIEDEIA | phosphorylation down-regulates | 20231902 | SIGNOR-252509 |
| AKT1 | ACAP1 | Ser554 | SIRPRPGsLRSKPEP | phosphorylation unknown | 16256741 | SIGNOR-252483 |
| AKT1 | BRAF | Ser365 | GQRDRSSsAPNVHIN | phosphorylation down-regulates activity | 10869359 | SIGNOR-251471 |
| AKT1 | TBC1D4 | Thr642 | QFRRRAHtFSHPPSS | phosphorylation unknown | 16880201 | SIGNOR-252494 |
| AKT1 | MVD | Ser96 | LARKRRNsRDGDPLP | phosphorylation up-regulates activity | 25378391 | SIGNOR-265891 |
| AKT1 | AKT1S1 | Thr246 | LPRPRLNtSDFQKLK | phosphorylation down-regulates activity | 12524439 | SIGNOR-252544 |
| AKT1 | TKT | Thr382 | GCATRNRtVPFCSTF | phosphorylation up-regulates activity | 24981175 | SIGNOR-265101 |
| AKT1 | KDM5A | Thr1225 | SRRPRLEtILSLLVS | phosphorylation up-regulates activity | 27292631 | SIGNOR-274063 |
| AKT1 | FOXO | Ser197 | APRRRAAsMDSSSKL | phosphorylation down-regulates activity | 10217147 | SIGNOR-252861 |
| AKT1 | CARD11 | Ser652 | LERPFRPsVTSVGHV | phosphorylation up-regulates activity | 24548923 | SIGNOR-276620 |
| AKT1 | SH2B2 | Ser598 | SARSRSNsAERLLEA | phosphorylation unknown | 16141217 | SIGNOR-252577 |
| AKT1 | TARBP2 | Ser286 | LRSCSLGsLGALGPA | phosphorylation up-regulates activity | 27407113 | SIGNOR-274067 |
| AKT1 | mTORC1 | – | phosphorylation up-regulates activity | 17130464 | SIGNOR-252540 | |
| AKT1 | ESR1 | Ser104 | FPPLNSVsPSPLMLL | phosphorylation up-regulates | 11108261 | SIGNOR-84963 |
| AKT1 | FOXO3 | – | phosphorylation down-regulates activity | 21798082 | SIGNOR-175288 | |
| AKT1 | MASTL | Thr299 | QSRKRLAtSSASSQS | phosphorylation up-regulates activity | 32123010 | SIGNOR-277515 |
| AKT1 | MAP2K4 | Ser80 | IERLRTHsIESSGKL | phosphorylation down-regulates | 11707464 | SIGNOR-236494 |
| AKT1 | SP7 | – | phosphorylation up-regulates | 21777568 | SIGNOR-195549 | |
| AKT1 | FOXO1 | – | phosphorylation down-regulates | 21798082 | SIGNOR-175285 | |
| AKT1 | LTB4R2 | Thr324 | GGRSREGtMELRTTP | phosphorylation unknown | 22044535 | SIGNOR-252516 |
| AKT1 | PTK2 | Ser695 | EERMRMEsRRQATVS | phosphorylation up-regulates activity | 23264741 | SIGNOR-276437 |
| AKT1 | GSK3B | Ser9 | SGRPRTTsFAESCKP | phosphorylation down-regulates activity | 23552696 | SIGNOR-245416 |
| AKT1 | FOXO3 | Ser315 | DFRSRTNsNASTVSG | phosphorylation down-regulates quantity by destabilization | 19951971 | SIGNOR-249627 |
| AKT1 | NR3C1 | Ser134 | ANLNRSTsVPENPKS | phosphorylation down-regulates | 24291004 | SIGNOR-252543 |
| AKT1 | CDKN1A | Ser146 | GRKRRQTsMTDFYHS | phosphorylation up-regulates quantity by stabilization | 31575057 | SIGNOR-157790 |
| AKT1 | CASP9 | Ser196 | KLRRRFSsLHFMVEV | phosphorylation down-regulates | 15004527 | SIGNOR-252472 |
| AKT1 | ACLY | Ser455 | PAPSRTAsFSESRAD | phosphorylation unknown | 12107176 | SIGNOR-245255 |
| AKT1 | MXD1 | Ser145 | IERIRMDsIGSTVSS | phosphorylation down-regulates | 19526459 | SIGNOR-252525 |
| AKT1 | CCT2 | Ser260 | GSRVRVDsTAKVAEI | phosphorylation unknown | 19332537 | SIGNOR-184922 |
| AKT1 | NCOR1 | Ser1450 | TVRSRHTsVVSSGPS | phosphorylation down-regulates | 23940660 | SIGNOR-198913 |
| AKT1 | SKP2 | Ser72 | PPRKRLKsKGSDKDF | phosphorylation down-regulates activity | 19270695 | SIGNOR-278274 |
| AKT1 | ITCH | Ser257 | PSRPPRPsRPPPPTP | phosphorylation up-regulates quantity | 30517763 | SIGNOR-272922 |
| AKT1 | MITF | Ser516 | KTSSRRSsMSMEETE | phosphorylation down-regulates quantity by destabilization | 27702651 | SIGNOR-277281 |
| AKT1 | PDE3B | Ser295 | VIRPRRRsSCVSLGE | phosphorylation up-regulates | 10454575 | SIGNOR-252583 |
| AKT1 | NUAK1 | Ser600 | PARQRIRsCVSAENF | phosphorylation up-regulates | 12409306 | SIGNOR-252591 |
| AKT1 | ZFP36L1 | Ser92 | RFRDRSFsEGGERLL | phosphorylation down-regulates | 15538381 | SIGNOR-130376 |
| AKT1 | NPM1 | Ser48 | QLSLRTVsLGAGAKD | phosphorylation down-regulates activity | 25071014 | SIGNOR-276667 |
| AKT1 | NR4A1 | Ser351 | GRRGRLPsKPKQPPD | phosphorylation down-regulates activity | 11274386 | SIGNOR-252466 |
| AKT1 | YBX1 | Ser102 | NPRKYLRsVGDGETV | phosphorylation up-regulates | 15806160 | SIGNOR-252475 |
| AKT1 | NQO1 | Ser40 | KGWEVVEsDLYAMNF | phosphorylation down-regulates quantity by destabilization | 31358653 | SIGNOR-276868 |
| AKT1 | CYCS | Tyr47 | KTGQAPGySYTAANK | phosphorylation down-regulates activity | 32781572 | SIGNOR-277237 |
| AKT1 | mTORC1 | – | phosphorylation up-regulates | 15829723 | SIGNOR-255844 | |
| AKT1 | FOXO | Ser262 | TFRPRSSsNASSVST | phosphorylation down-regulates | 16272144 | SIGNOR-252854 |
| AKT1 | MTOR | – | phosphorylation up-regulates | 15829723 | SIGNOR-255107 |
| Enzyme | Effect | Phosphosite | Effect | Target | PMID | Interaction ID |
|---|---|---|---|---|---|---|
| AKT1 | phosphorylation up-regulates → | ACOT4 PSer392 | phosphorylation up-regulates → | ACOT4 | 33148467 | SIGNOR-271820 |
| AKT1 | phosphorylation up-regulates → | METTL1 PSer27 | phosphorylation down-regulates ⊣ | METTL1 | 3627513 | SIGNOR-24994 |
| AKT1 | phosphorylation up-regulates → | YBX1 PSer102 | phosphorylation up-regulates → | YBX1 | 19036157 | SIGNOR-252521 |
| AKT1 | phosphorylation up-regulates → | CARD11 PSer652 | phosphorylation up-regulates → | CARD11 | 24548923 | SIGNOR-276256 |
| AKT1 | phosphorylation up-regulates → | CASP9 PSer196 | phosphorylation down-regulates ⊣ | CASP9 | 9812896 | SIGNOR-252581 |
| AKT1 | phosphorylation up-regulates → | TERT PSer824 | phosphorylation up-regulates → | TERT | 10224060 | SIGNOR-67317 |
| AKT1 | phosphorylation up-regulates → | ESR1 PSer167 | phosphorylation up-regulates → | ESR1 | 11108261 | SIGNOR-84975 |
| AKT1 | phosphorylation up-regulates → | EP300 PSer1834 | phosphorylation up-regulates → | EP300 | 16926151 | SIGNOR-148983 |
| AKT1 | phosphorylation up-regulates → | FOXO3 PThr32 | phosphorylation down-regulates ⊣ | FOXO3 | 19188143 | SIGNOR-252524 |
| AKT1 | phosphorylation up-regulates → | FOXO PSer315 | phosphorylation down-regulates ⊣ | FOXO | 19951971 | SIGNOR-252845 |
| AKT1 | phosphorylation up-regulates → | CTNNB1 PSer552 | phosphorylation up-regulates → | CTNNB1 | 17287208 | SIGNOR-252499 |
| AKT1 | phosphorylation up-regulates → | BLVRA PSer230 | phosphorylation up-regulates → | BLVRA | 15870194 | SIGNOR-275517 |
| AKT1 | phosphorylation up-regulates → | RANBP3 PSer126 | phosphorylation down-regulates ⊣ | RANBP3 | 18280241 | SIGNOR-252504 |
| AKT1 | phosphorylation up-regulates → | PHF20 PSer291 | phosphorylation down-regulates ⊣ | PHF20 | 22334668 | SIGNOR-252529 |
| AKT1 | phosphorylation up-regulates → | CELF1 PSer28 | phosphorylation up-regulates → | CELF1 | 18570922 | SIGNOR-280173 |
| AKT1 | phosphorylation up-regulates → | GAPDH PThr237 | phosphorylation down-regulates ⊣ | GAPDH | 23332158 | SIGNOR-280174 |
| AKT1 | phosphorylation up-regulates → | UPF1 PThr151 | phosphorylation up-regulates → | UPF1 | 35675814 | SIGNOR-277597 |
| AKT1 | phosphorylation up-regulates → | DOCK6 PSer1194 | phosphorylation up-regulates → | DOCK6 | 23462102 | SIGNOR-275666 |
| AKT1 | phosphorylation up-regulates → | FOXO PSer253 | phosphorylation down-regulates ⊣ | FOXO | 19951971 | SIGNOR-252844 |
| AKT1 | phosphorylation up-regulates → | FBXO31 PSer33 | phosphorylation down-regulates ⊣ | FBXO31 | 29343641 | SIGNOR-277376 |
| AKT1 | phosphorylation up-regulates → | SIRT6 PSer338 | phosphorylation down-regulates ⊣ | SIRT6 | 25074979 | SIGNOR-278465 |
| AKT1 | phosphorylation up-regulates → | MDM2 PSer166 | phosphorylation up-regulates → | MDM2 | 11504915 | SIGNOR-116270 |
| AKT1 | phosphorylation up-regulates → | BAD PSer75 | phosphorylation down-regulates ⊣ | BAD | 9381178 | SIGNOR-252562 |
| AKT1 | phosphorylation up-regulates → | SRPK2 PThr492 | phosphorylation up-regulates → | SRPK2 | 19592491 | SIGNOR-186760 |
| AKT1 | phosphorylation up-regulates → | CABLES1 PThr309 | phosphorylation down-regulates ⊣ | CABLES1 | 25361894 | SIGNOR-276756 |
| AKT1 | phosphorylation up-regulates → | GSK3B PSer9 | phosphorylation down-regulates ⊣ | GSK3B | 9373175 | SIGNOR-252546 |
| AKT1 | phosphorylation up-regulates → | ADAR PThr1033 | phosphorylation down-regulates ⊣ | ADAR | 31095429 | SIGNOR-276193 |
| AKT1 | phosphorylation up-regulates → | FOXO PThr32 | phosphorylation down-regulates ⊣ | FOXO | 19188143 | SIGNOR-252848 |
| AKT1 | phosphorylation up-regulates → | PDCD4 PSer67 | phosphorylation down-regulates ⊣ | PDCD4 | 17053147 | SIGNOR-252496 |
| AKT1 | phosphorylation up-regulates → | BAD PSer99 | phosphorylation down-regulates ⊣ | BAD | 9381178 | SIGNOR-252563 |
| AKT1 | phosphorylation up-regulates → | LARP1 PSer847 | phosphorylation down-regulates ⊣ | LARP1 | 28650797 | SIGNOR-260991 |
| AKT1 | phosphorylation up-regulates → | CDKN1C PThr310 | phosphorylation down-regulates ⊣ | CDKN1C | 23421998 | SIGNOR-252536 |
| AKT1 | phosphorylation up-regulates → | PTK2 PSer601 | phosphorylation up-regulates → | PTK2 | 31138602 | SIGNOR-279775 |
| AKT1 | phosphorylation up-regulates → | PTK2 PSer695 | phosphorylation up-regulates → | PTK2 | 31138602 | SIGNOR-279776 |
| AKT1 | phosphorylation up-regulates → | HSF1 PSer230 | phosphorylation up-regulates → | HSF1 | 35080342 | SIGNOR-278373 |
| AKT1 | phosphorylation up-regulates → | MDM2 PSer186 | phosphorylation up-regulates → | MDM2 | 11504915 | SIGNOR-116274 |
| AKT1 | phosphorylation up-regulates → | MAP3K11 PSer674 | phosphorylation down-regulates ⊣ | MAP3K11 | 12458207 | SIGNOR-252592 |
| AKT1 | phosphorylation up-regulates → | SH2B2 PSer598 | phosphorylation up-regulates → | SH2B2 | 16141217 | SIGNOR-252557 |
| AKT1 | phosphorylation up-regulates → | EZH2 PSer21 | phosphorylation down-regulates ⊣ | EZH2 | 16224021 | SIGNOR-141043 |
| AKT1 | phosphorylation up-regulates → | BECN1 PSer295 | phosphorylation down-regulates ⊣ | BECN1 | 31852899 | SIGNOR-279667 |
| AKT1 | phosphorylation up-regulates → | HSF1 PSer326 | phosphorylation up-regulates → | HSF1 | 35080342 | SIGNOR-277581 |
| AKT1 | phosphorylation up-regulates → | RARG PSer371 | phosphorylation up-regulates → | RARG | 31740618 | SIGNOR-277492 |
| AKT1 | phosphorylation up-regulates → | FOXO3 PSer253 | phosphorylation down-regulates ⊣ | FOXO3 | 19951971 | SIGNOR-249626 |
| AKT1 | phosphorylation up-regulates → | HSF1 PThr527 | phosphorylation up-regulates → | HSF1 | 35080342 | SIGNOR-277578 |
| AKT1 | phosphorylation up-regulates → | PDK1 PThr346 | phosphorylation up-regulates → | PDK1 | 27505672 | SIGNOR-277272 |
| AKT1 | phosphorylation up-regulates → | ADRB2 PSer345 | phosphorylation down-regulates ⊣ | ADRB2 | 11809767 | SIGNOR-252469 |
| AKT1 | phosphorylation up-regulates → | CREB1 PSer119 | phosphorylation up-regulates → | CREB1 | 9829964 | SIGNOR-252549 |
| AKT1 | phosphorylation up-regulates → | ARFIP2 PSer260 | phosphorylation down-regulates ⊣ | ARFIP2 | 15809304 | SIGNOR-252476 |
| AKT1 | phosphorylation up-regulates → | TWIST1 PSer42 | phosphorylation up-regulates → | TWIST1 | 20400976 | SIGNOR-164884 |
| AKT1 | phosphorylation up-regulates → | NCF1 PSer328 | phosphorylation up-regulates → | NCF1 | 10559253 | SIGNOR-252587 |
| AKT1 | phosphorylation up-regulates → | HTRA2 PSer212 | phosphorylation down-regulates ⊣ | HTRA2 | 17311912 | SIGNOR-252500 |
| AKT1 | phosphorylation up-regulates → | GSK3A PSer21 | phosphorylation down-regulates ⊣ | GSK3A | 11035810 | SIGNOR-252589 |
| AKT1 | phosphorylation up-regulates → | CDCA7 PThr163 | phosphorylation down-regulates ⊣ | CDCA7 | 23166294 | SIGNOR-252533 |
| AKT1 | phosphorylation up-regulates → | YAP1 PSer127 | phosphorylation down-regulates ⊣ | YAP1 | 12535517 | SIGNOR-252593 |
| AKT1 | phosphorylation up-regulates → | PFKFB2 PSer483 | phosphorylation down-regulates ⊣ | PFKFB2 | 12853467 | SIGNOR-252575 |
| AKT1 | phosphorylation up-regulates → | PALLD PSer1118 | phosphorylation down-regulates ⊣ | PALLD | 20471940 | SIGNOR-252510 |
| AKT1 | phosphorylation up-regulates → | VCP PSer746 | phosphorylation up-regulates → | VCP | 16551632 | SIGNOR-252492 |
| AKT1 | phosphorylation up-regulates → | FOXO PThr24 | phosphorylation down-regulates ⊣ | FOXO | 10377430 | SIGNOR-252857 |
| AKT1 | phosphorylation up-regulates → | HSF1 PThr142 | phosphorylation up-regulates → | HSF1 | 35080342 | SIGNOR-277579 |
| AKT1 | phosphorylation up-regulates → | TARBP2 PSer283 | phosphorylation up-regulates → | TARBP2 | 27407113 | SIGNOR-274064 |
| AKT1 | phosphorylation up-regulates → | FOXO3 PSer253 | phosphorylation down-regulates ⊣ | FOXO3 | 19188143 | SIGNOR-252522 |
| AKT1 | phosphorylation up-regulates → | RPS6KA3 PSer19 | phosphorylation down-regulates ⊣ | RPS6KA3 | 33574926 | SIGNOR-277548 |
| AKT1 | phosphorylation up-regulates → | PEA15 PSer116 | phosphorylation up-regulates → | PEA15 | 12808093 | SIGNOR-102092 |
| AKT1 | phosphorylation up-regulates → | PFKFB2 PSer483 | phosphorylation up-regulates → | PFKFB2 | 23457334 | SIGNOR-252528 |
| AKT1 | phosphorylation up-regulates → | S1PR1 PThr236 | phosphorylation up-regulates → | S1PR1 | 11583630 | SIGNOR-252467 |
| AKT1 | phosphorylation up-regulates → | MST1R PSer1394 | phosphorylation up-regulates → | MST1R | 14505491 | SIGNOR-252471 |
| AKT1 | phosphorylation up-regulates → | TSC2 PSer939 | phosphorylation down-regulates ⊣ | TSC2 | 12150915 | SIGNOR-235511 |
| AKT1 | phosphorylation up-regulates → | STK4 PThr387 | phosphorylation down-regulates ⊣ | STK4 | 23431053 | SIGNOR-252537 |
| AKT1 | phosphorylation up-regulates → | PFKFB2 PSer466 | phosphorylation down-regulates ⊣ | PFKFB2 | 12853467 | SIGNOR-252574 |
| AKT1 | phosphorylation up-regulates → | LONP1 PSer173 | phosphorylation up-regulates → | LONP1 | 31406245 | SIGNOR-265724 |
| AKT1 | phosphorylation up-regulates → | BMI1 PSer316 | phosphorylation up-regulates → | BMI1 | 22505453 | SIGNOR-252559 |
| AKT1 | phosphorylation up-regulates → | STK4 PThr120 | phosphorylation down-regulates ⊣ | STK4 | 19940129 | SIGNOR-252507 |
| AKT1 | phosphorylation up-regulates → | BRCA1 PSer694 | phosphorylation up-regulates → | BRCA1 | 20085797 | SIGNOR-163472 |
| AKT1 | phosphorylation up-regulates → | FOXO3 PSer315 | phosphorylation down-regulates ⊣ | FOXO3 | 19188143 | SIGNOR-252523 |
| AKT1 | phosphorylation up-regulates → | PDE3B PSer318 | phosphorylation up-regulates → | PDE3B | 10454575 | SIGNOR-252554 |
| AKT1 | phosphorylation up-regulates → | DNMT1 PSer143 | phosphorylation up-regulates → | DNMT1 | 21151116 | SIGNOR-170530 |
| AKT1 | phosphorylation up-regulates → | CARD11 PSer558 | phosphorylation up-regulates → | CARD11 | 24548923 | SIGNOR-276254 |
| AKT1 | phosphorylation up-regulates → | ESR1 PSer118 | phosphorylation up-regulates → | ESR1 | 11108261 | SIGNOR-84971 |
| AKT1 | phosphorylation up-regulates → | FOXO PSer256 | phosphorylation down-regulates ⊣ | FOXO | 10377430 | SIGNOR-252856 |
| AKT1 | phosphorylation up-regulates → | PLN PThr17 | phosphorylation down-regulates ⊣ | PLN | 19696029 | SIGNOR-252578 |
| AKT1 | phosphorylation up-regulates → | CLK2 PSer34 | phosphorylation up-regulates → | CLK2 | 20682768 | SIGNOR-167336 |
| AKT1 | phosphorylation up-regulates → | FOXO PSer262 | phosphorylation down-regulates ⊣ | FOXO | 10217147 | SIGNOR-252862 |
| AKT1 | phosphorylation up-regulates → | BCL2L11 PSer87 | phosphorylation down-regulates ⊣ | BCL2L11 | 16282323 | SIGNOR-252487 |
| AKT1 | phosphorylation up-regulates → | FOXO PSer315 | phosphorylation down-regulates ⊣ | FOXO | 19188143 | SIGNOR-252850 |
| AKT1 | phosphorylation up-regulates → | TMIGD2 PSer220 | phosphorylation up-regulates → | TMIGD2 | 31341021 | SIGNOR-273481 |
| AKT1 | phosphorylation up-regulates → | HSF1 PThr527 | phosphorylation up-regulates → | HSF1 | 35080342 | SIGNOR-278371 |
| AKT1 | phosphorylation up-regulates → | GATA1 PSer310 | phosphorylation up-regulates → | GATA1 | 16107690 | SIGNOR-139782 |
| AKT1 | phosphorylation up-regulates → | ESR1 PSer106 | phosphorylation up-regulates → | ESR1 | 11108261 | SIGNOR-84967 |
| AKT1 | phosphorylation up-regulates → | MAPKAP1 PThr86 | phosphorylation up-regulates → | MAPKAP1 | 26235620 | SIGNOR-276932 |
| AKT1 | phosphorylation up-regulates → | SKI PThr458 | phosphorylation down-regulates ⊣ | SKI | 19875456 | SIGNOR-252527 |
| AKT1 | phosphorylation up-regulates → | NIBAN1 PSer602 | phosphorylation down-regulates ⊣ | NIBAN1 | 22510990 | SIGNOR-252530 |
| AKT1 | phosphorylation up-regulates → | KDM5A PThr285 | phosphorylation up-regulates → | KDM5A | 27292631 | SIGNOR-274061 |
| AKT1 | phosphorylation up-regulates → | MAP3K5 PSer83 | phosphorylation down-regulates ⊣ | MAP3K5 | 11154276 | SIGNOR-252465 |
| AKT1 | phosphorylation up-regulates → | TAL1 PThr90 | phosphorylation down-regulates ⊣ | TAL1 | 15930267 | SIGNOR-252479 |
| AKT1 | phosphorylation up-regulates → | MAP3K8 PSer413 | phosphorylation up-regulates → | MAP3K8 | 12138205 | SIGNOR-252572 |
| AKT1 | phosphorylation up-regulates → | AR PSer792 | phosphorylation down-regulates ⊣ | AR | 11404460 | SIGNOR-108508 |
| AKT1 | phosphorylation up-regulates → | WNK1 PThr60 | phosphorylation up-regulates → | WNK1 | 16081417 | SIGNOR-252481 |
| AKT1 | phosphorylation up-regulates → | PARK7 PThr125 | phosphorylation up-regulates → | PARK7 | 32858971 | SIGNOR-275582 |
| AKT1 | phosphorylation up-regulates → | PTK2 PThr700 | phosphorylation up-regulates → | PTK2 | 31138602 | SIGNOR-279777 |
| AKT1 | phosphorylation up-regulates → | SMURF1 PThr145 | phosphorylation up-regulates → | SMURF1 | 27036023 | SIGNOR-279778 |
| AKT1 | phosphorylation up-regulates → | EPHA2 PSer897 | phosphorylation up-regulates → | EPHA2 | 35869144 | SIGNOR-279787 |
| AKT1 | phosphorylation up-regulates → | FOXO1 PSer256 | phosphorylation down-regulates ⊣ | FOXO1 | 10377430 | SIGNOR-236159 |
| AKT1 | phosphorylation up-regulates → | RAB3IP PSer165 | phosphorylation up-regulates → | RAB3IP | 36797475 | SIGNOR-277802 |
| AKT1 | phosphorylation up-regulates → | LARP6 PSer451 | phosphorylation up-regulates → | LARP6 | 26932461 | SIGNOR-277213 |
| AKT1 | phosphorylation up-regulates → | CFLAR PSer273 | phosphorylation down-regulates ⊣ | CFLAR | 19339247 | SIGNOR-252548 |
| AKT1 | phosphorylation up-regulates → | ADARB1 PThr553 | phosphorylation down-regulates ⊣ | ADARB1 | 31095429 | SIGNOR-276194 |
| AKT1 | phosphorylation up-regulates → | CLK2 PThr127 | phosphorylation up-regulates → | CLK2 | 20682768 | SIGNOR-167340 |
| AKT1 | phosphorylation up-regulates → | RNF11 PThr135 | phosphorylation down-regulates ⊣ | RNF11 | 16123141 | SIGNOR-252558 |
| AKT1 | phosphorylation up-regulates → | RAF1 PSer259 | phosphorylation down-regulates ⊣ | RAF1 | 16854453 | SIGNOR-147963 |
| AKT1 | phosphorylation up-regulates → | FOXO PSer197 | phosphorylation down-regulates ⊣ | FOXO | 16272144 | SIGNOR-252853 |
| AKT1 | phosphorylation up-regulates → | PTK2 PSer517 | phosphorylation up-regulates → | PTK2 | 31138602 | SIGNOR-279774 |
| AKT1 | phosphorylation up-regulates → | PFKFB3 PSer461 | phosphorylation up-regulates → | PFKFB3 | 15896703 | SIGNOR-252477 |
| AKT1 | phosphorylation up-regulates → | FOXO PThr32 | phosphorylation down-regulates ⊣ | FOXO | 19951971 | SIGNOR-252846 |
| AKT1 | phosphorylation up-regulates → | SH3RF1 PSer304 | phosphorylation down-regulates ⊣ | SH3RF1 | 17535800 | SIGNOR-252501 |
| AKT1 | phosphorylation up-regulates → | FANCA PSer1149 | phosphorylation down-regulates ⊣ | FANCA | 11855836 | SIGNOR-252567 |
| AKT1 | phosphorylation up-regulates → | AKT1 PThr72 | phosphorylation up-regulates → | AKT1 | 16549426 | SIGNOR-276054 |
| AKT1 | phosphorylation up-regulates → | MDM4 PSer367 | phosphorylation up-regulates → | MDM4 | 18356162 | SIGNOR-252517 |
| AKT1 | phosphorylation up-regulates → | ALYREF PThr219 | phosphorylation up-regulates → | ALYREF | 18562279 | SIGNOR-252518 |
| AKT1 | phosphorylation up-regulates → | STK3 PThr384 | phosphorylation down-regulates ⊣ | STK3 | 20086174 | SIGNOR-163537 |
| AKT1 | phosphorylation up-regulates → | FOXO3 PThr32 | phosphorylation down-regulates ⊣ | FOXO3 | 19951971 | SIGNOR-249625 |
| AKT1 | phosphorylation up-regulates → | CBY1 PSer20 | phosphorylation up-regulates → | CBY1 | 18573912 | SIGNOR-279002 |
| AKT1 | phosphorylation up-regulates → | CABLES1 PThr415 | phosphorylation down-regulates ⊣ | CABLES1 | 25361894 | SIGNOR-276757 |
| AKT1 | phosphorylation up-regulates → | USP14 PSer432 | phosphorylation up-regulates → | USP14 | 26523394 | SIGNOR-265056 |
| AKT1 | phosphorylation up-regulates → | PIKFYVE PSer307 | phosphorylation up-regulates → | PIKFYVE | 15546921 | SIGNOR-252474 |
| AKT1 | phosphorylation up-regulates → | H3-3A PSer11 | phosphorylation down-regulates ⊣ | H3-3A | 12588998 | SIGNOR-98285 |
| AKT1 | phosphorylation up-regulates → | GATA2 PSer401 | phosphorylation down-regulates ⊣ | GATA2 | 15837948 | SIGNOR-135614 |
| AKT1 | phosphorylation up-regulates → | CHEK1 PSer280 | phosphorylation down-regulates ⊣ | CHEK1 | 15107605 | SIGNOR-124365 |
| AKT1 | phosphorylation up-regulates → | FOXO4 PSer262 | phosphorylation down-regulates ⊣ | FOXO4 | 10217147 | SIGNOR-252569 |
| AKT1 | phosphorylation up-regulates → | SOX2 PThr118 | phosphorylation up-regulates → | SOX2 | 25042802 | SIGNOR-279003 |
| AKT1 | phosphorylation up-regulates → | FOXO4 PThr32 | phosphorylation down-regulates ⊣ | FOXO4 | 16272144 | SIGNOR-252486 |
| AKT1 | phosphorylation up-regulates → | TERT PSer227 | phosphorylation up-regulates → | TERT | 10224060 | SIGNOR-67313 |
| AKT1 | phosphorylation up-regulates → | ADRB2 PSer346 | phosphorylation down-regulates ⊣ | ADRB2 | 11809767 | SIGNOR-252470 |
| AKT1 | phosphorylation up-regulates → | HK2 PThr473 | phosphorylation up-regulates → | HK2 | 31435020 | SIGNOR-259984 |
| AKT1 | phosphorylation up-regulates → | ITGB3 PThr779 | phosphorylation down-regulates ⊣ | ITGB3 | 10896934 | SIGNOR-252552 |
| AKT1 | phosphorylation up-regulates → | POU5F1 PThr235 | phosphorylation up-regulates → | POU5F1 | 23041284 | SIGNOR-252545 |
| AKT1 | phosphorylation up-regulates → | ZRANB1 PThr117 | phosphorylation up-regulates → | ZRANB1 | 29748601 | SIGNOR-273484 |
| AKT1 | phosphorylation up-regulates → | MAP3K8 PSer400 | phosphorylation up-regulates → | MAP3K8 | 12138205 | SIGNOR-252571 |
| AKT1 | phosphorylation up-regulates → | AKT1 PSer246 | phosphorylation up-regulates → | AKT1 | 16549426 | SIGNOR-276055 |
| AKT1 | phosphorylation up-regulates → | VCP PSer352 | phosphorylation up-regulates → | VCP | 16551632 | SIGNOR-252491 |
| AKT1 | phosphorylation up-regulates → | CDKN1B PThr198 | phosphorylation down-regulates ⊣ | CDKN1B | 12042314 | SIGNOR-88294 |
| AKT1 | phosphorylation up-regulates → | CHUK PThr23 | phosphorylation up-regulates → | CHUK | 19609947 | SIGNOR-187006 |
| AKT1 | phosphorylation up-regulates → | CARD11 PSer644 | phosphorylation up-regulates → | CARD11 | 24548923 | SIGNOR-276255 |
| AKT1 | phosphorylation up-regulates → | FOXO1 PSer319 | phosphorylation down-regulates ⊣ | FOXO1 | 11237865 | SIGNOR-105459 |
| AKT1 | phosphorylation up-regulates → | PDCD4 PSer67 | phosphorylation down-regulates ⊣ | PDCD4 | 18296647 | SIGNOR-252505 |
| AKT1 | phosphorylation up-regulates → | TSC2 PThr1462 | phosphorylation down-regulates ⊣ | TSC2 | 12150915 | SIGNOR-235515 |
| AKT1 | phosphorylation up-regulates → | CARHSP1 PSer52 | phosphorylation down-regulates ⊣ | CARHSP1 | 15910284 | SIGNOR-252478 |
| AKT1 | phosphorylation up-regulates → | RAF1 PSer259 | phosphorylation down-regulates ⊣ | RAF1 | 10576741 | SIGNOR-252588 |
| AKT1 | phosphorylation up-regulates → | STK3 PThr117 | phosphorylation down-regulates ⊣ | STK3 | 20086174 | SIGNOR-163533 |
| AKT1 | phosphorylation up-regulates → | CDKN1C PSer282 | phosphorylation down-regulates ⊣ | CDKN1C | 23421998 | SIGNOR-252535 |
| AKT1 | phosphorylation up-regulates → | CASP9 PSer196 | phosphorylation down-regulates ⊣ | CASP9 | 10529400 | SIGNOR-252585 |
| AKT1 | phosphorylation up-regulates → | TTC3 PSer378 | phosphorylation up-regulates → | TTC3 | 20059950 | SIGNOR-252508 |
| AKT1 | phosphorylation up-regulates → | PIK3R6 PThr607 | phosphorylation up-regulates → | PIK3R6 | 25753393 | SIGNOR-275722 |
| AKT1 | phosphorylation up-regulates → | BRAF PSer429 | phosphorylation down-regulates ⊣ | BRAF | 10869359 | SIGNOR-251472 |
| AKT1 | phosphorylation up-regulates → | XIAP PSer87 | phosphorylation up-regulates → | XIAP | 14645242 | SIGNOR-119488 |
| AKT1 | phosphorylation up-regulates → | KDM5A PSer225 | phosphorylation up-regulates → | KDM5A | 27292631 | SIGNOR-274060 |
| AKT1 | phosphorylation up-regulates → | ZYX PSer142 | phosphorylation down-regulates ⊣ | ZYX | 17572661 | SIGNOR-156122 |
| AKT1 | phosphorylation up-regulates → | PTK2 PThr700 | phosphorylation up-regulates → | PTK2 | 23264741 | SIGNOR-276436 |
| AKT1 | phosphorylation up-regulates → | BTK PThr495 | phosphorylation down-regulates ⊣ | BTK | 23754751 | SIGNOR-276465 |
| AKT1 | phosphorylation up-regulates → | LONP1 PSer181 | phosphorylation up-regulates → | LONP1 | 31406245 | SIGNOR-265725 |
| AKT1 | phosphorylation up-regulates → | USP4 PSer445 | phosphorylation up-regulates → | USP4 | 22706160 | SIGNOR-273482 |
| AKT1 | phosphorylation up-regulates → | BCL3 PSer41 | phosphorylation up-regulates → | BCL3 | 28689659 | SIGNOR-277358 |
| AKT1 | phosphorylation up-regulates → | LARP1 PSer1056 | phosphorylation down-regulates ⊣ | LARP1 | 28650797 | SIGNOR-260992 |
| AKT1 | phosphorylation up-regulates → | FOXO4 PSer197 | phosphorylation down-regulates ⊣ | FOXO4 | 10217147 | SIGNOR-252568 |
| AKT1 | phosphorylation up-regulates → | RAC1 PSer71 | phosphorylation down-regulates ⊣ | RAC1 | 10617634 | SIGNOR-252576 |
| AKT1 | phosphorylation up-regulates → | HMOX1 PSer188 | phosphorylation down-regulates ⊣ | HMOX1 | 15581622 | SIGNOR-252506 |
| AKT1 | phosphorylation up-regulates → | NOS3 PSer1177 | phosphorylation up-regulates → | NOS3 | 11729179 | SIGNOR-112363 |
| AKT1 | phosphorylation up-regulates → | HSF1 PThr142 | phosphorylation up-regulates → | HSF1 | 35080342 | SIGNOR-278372 |
| AKT1 | phosphorylation up-regulates → | BAX PSer184 | phosphorylation down-regulates ⊣ | BAX | 14766748 | SIGNOR-252538 |
| AKT1 | phosphorylation up-regulates → | ATG4B PSer34 | phosphorylation up-regulates → | ATG4B | 29165041 | SIGNOR-275834 |
| AKT1 | phosphorylation up-regulates → | RPS3 PThr70 | phosphorylation up-regulates → | RPS3 | 20605787 | SIGNOR-259815 |
| AKT1 | phosphorylation up-regulates → | FOXO1 PThr24 | phosphorylation down-regulates ⊣ | FOXO1 | 10377430 | SIGNOR-236163 |
| AKT1 | phosphorylation up-regulates → | MDM2 PSer188 | phosphorylation up-regulates → | MDM2 | 15169778 | SIGNOR-124953 |
| AKT1 | phosphorylation up-regulates → | BRCA1 PThr509 | phosphorylation up-regulates → | BRCA1 | 17428466 | SIGNOR-154312 |
| AKT1 | phosphorylation up-regulates → | HSF1 PSer326 | phosphorylation up-regulates → | HSF1 | 35080342 | SIGNOR-278374 |
| AKT1 | phosphorylation up-regulates → | NOS3 PSer615 | phosphorylation up-regulates → | NOS3 | 24379783 | SIGNOR-251622 |
| AKT1 | phosphorylation up-regulates → | PFKFB2 PSer466 | phosphorylation up-regulates → | PFKFB2 | 10521487 | SIGNOR-252584 |
| AKT1 | phosphorylation up-regulates → | HTT PSer419 | phosphorylation down-regulates ⊣ | HTT | 12062094 | SIGNOR-252590 |
| AKT1 | phosphorylation up-regulates → | CARD11 PSer644 | phosphorylation up-regulates → | CARD11 | 24548923 | SIGNOR-276621 |
| AKT1 | phosphorylation up-regulates → | RARA PSer96 | phosphorylation down-regulates ⊣ | RARA | 16417524 | SIGNOR-252489 |
| AKT1 | phosphorylation up-regulates → | BECN1 PSer234 | phosphorylation down-regulates ⊣ | BECN1 | 31852899 | SIGNOR-279666 |
| AKT1 | phosphorylation up-regulates → | UBE2S PThr152 | phosphorylation up-regulates → | UBE2S | 27593939 | SIGNOR-265078 |
| AKT1 | phosphorylation up-regulates → | ZRANB1 PSer78 | phosphorylation up-regulates → | ZRANB1 | 29748601 | SIGNOR-273483 |
| AKT1 | phosphorylation up-regulates → | HSF1 PSer230 | phosphorylation up-regulates → | HSF1 | 35080342 | SIGNOR-277580 |
| AKT1 | phosphorylation up-regulates → | AGAP2 PSer985 | phosphorylation up-regulates → | AGAP2 | 19176382 | SIGNOR-183543 |
| AKT1 | phosphorylation up-regulates → | FOXO4 PSer197 | phosphorylation down-regulates ⊣ | FOXO4 | 16272144 | SIGNOR-252484 |
| AKT1 | phosphorylation up-regulates → | FOXO PSer319 | phosphorylation down-regulates ⊣ | FOXO | 11237865 | SIGNOR-252860 |
| AKT1 | phosphorylation up-regulates → | AR PSer215 | phosphorylation down-regulates ⊣ | AR | 17470458 | SIGNOR-154631 |
| AKT1 | phosphorylation up-regulates → | SOX2 PThr116 | phosphorylation up-regulates → | SOX2 | 30894683 | SIGNOR-277445 |
| AKT1 | phosphorylation up-regulates → | FOXO PSer253 | phosphorylation down-regulates ⊣ | FOXO | 19188143 | SIGNOR-252849 |
| AKT1 | phosphorylation up-regulates → | NQO1 PThr128 | phosphorylation down-regulates ⊣ | NQO1 | 31358653 | SIGNOR-276869 |
| AKT1 | phosphorylation up-regulates → | BAD PSer99 | phosphorylation down-regulates ⊣ | BAD | 9346240 | SIGNOR-52863 |
| AKT1 | phosphorylation up-regulates → | SYTL1 PSer241 | phosphorylation down-regulates ⊣ | SYTL1 | 15998322 | SIGNOR-273540 |
| AKT1 | phosphorylation up-regulates → | DAB2IP PSer971 | phosphorylation down-regulates ⊣ | DAB2IP | 27858941 | SIGNOR-254780 |
| AKT1 | phosphorylation up-regulates → | FBXW7 PSer227 | phosphorylation up-regulates → | FBXW7 | 21620836 | SIGNOR-276328 |
| AKT1 | phosphorylation up-regulates → | NCF1 PSer304 | phosphorylation up-regulates → | NCF1 | 10559253 | SIGNOR-252586 |
| AKT1 | phosphorylation up-regulates → | CCDC88A PSer1417 | phosphorylation down-regulates ⊣ | CCDC88A | 16139227 | SIGNOR-252482 |
| AKT1 | phosphorylation up-regulates → | MDM2 PSer166 | phosphorylation up-regulates → | MDM2 | 15169778 | SIGNOR-124949 |
| AKT1 | phosphorylation up-regulates → | AR PSer215 | phosphorylation down-regulates ⊣ | AR | 11404460 | SIGNOR-108504 |
| AKT1 | phosphorylation up-regulates → | CDKN1A PThr145 | phosphorylation up-regulates → | CDKN1A | 16982699 | SIGNOR-149698 |
| AKT1 | phosphorylation up-regulates → | DLC1 PSer766 | phosphorylation down-regulates ⊣ | DLC1 | 16338927 | SIGNOR-252550 |
| AKT1 | phosphorylation up-regulates → | KDM5A PSer287 | phosphorylation up-regulates → | KDM5A | 27292631 | SIGNOR-274062 |
| AKT1 | phosphorylation up-regulates → | IRAK1 PThr100 | phosphorylation down-regulates ⊣ | IRAK1 | 11976320 | SIGNOR-252551 |
| AKT1 | phosphorylation up-regulates → | ILF3 PSer647 | phosphorylation up-regulates → | ILF3 | 20870937 | SIGNOR-252512 |
| AKT1 | phosphorylation up-regulates → | FOXO PThr32 | phosphorylation down-regulates ⊣ | FOXO | 16272144 | SIGNOR-252855 |
| AKT1 | phosphorylation up-regulates → | PTPN1 PSer50 | phosphorylation down-regulates ⊣ | PTPN1 | 11579209 | SIGNOR-252542 |
| AKT1 | phosphorylation up-regulates → | CDK2 PThr39 | phosphorylation up-regulates → | CDK2 | 18354084 | SIGNOR-178058 |
| AKT1 | phosphorylation up-regulates → | MTOR PSer2448 | phosphorylation down-regulates ⊣ | MTOR | 10910062 | SIGNOR-251099 |
| AKT1 | phosphorylation up-regulates → | GAB2 PSer159 | phosphorylation down-regulates ⊣ | GAB2 | 11782427 | SIGNOR-252468 |
| AKT1 | phosphorylation up-regulates → | FOXO4 PSer262 | phosphorylation down-regulates ⊣ | FOXO4 | 16272144 | SIGNOR-252485 |
| AKT1 | phosphorylation up-regulates → | BAD PSer118 | phosphorylation down-regulates ⊣ | BAD | 9346240 | SIGNOR-52859 |
| AKT1 | phosphorylation up-regulates → | PDE3B PSer295 | phosphorylation up-regulates → | PDE3B | 10454575 | SIGNOR-252573 |
| AKT1 | phosphorylation up-regulates → | PRKAA1 PSer496 | phosphorylation down-regulates ⊣ | PRKAA1 | 27784766 | SIGNOR-276461 |
| AKT1 | phosphorylation up-regulates → | RAB3IP PSer165 | phosphorylation up-regulates → | RAB3IP | 36797475 | SIGNOR-277816 |
| AKT1 | phosphorylation up-regulates → | TIFA PThr9 | phosphorylation up-regulates → | TIFA | 27965388 | SIGNOR-273542 |
| AKT1 | phosphorylation up-regulates → | KDM5A PSer1255 | phosphorylation up-regulates → | KDM5A | 27292631 | SIGNOR-274059 |
| AKT1 | phosphorylation up-regulates → | PPARGC1A PSer571 | phosphorylation down-regulates ⊣ | PPARGC1A | 17554339 | SIGNOR-252502 |
| AKT1 | phosphorylation up-regulates → | NHEJ1 PThr181 | phosphorylation down-regulates ⊣ | NHEJ1 | 25661488 | SIGNOR-276881 |
| AKT1 | phosphorylation up-regulates → | EIF4B PSer422 | phosphorylation up-regulates → | EIF4B | 18836482 | SIGNOR-252520 |
| AKT1 | phosphorylation up-regulates → | CDKN1B PThr157 | phosphorylation down-regulates ⊣ | CDKN1B | 18570873 | SIGNOR-179109 |
| AKT1 | phosphorylation up-regulates → | SCYL1 PThr469 | phosphorylation up-regulates → | SCYL1 | 24769208 | SIGNOR-265496 |
| AKT1 | phosphorylation up-regulates → | PFKFB2 PSer466 | phosphorylation up-regulates → | PFKFB2 | 12853467 | SIGNOR-252555 |
| AKT1 | phosphorylation up-regulates → | COPS6 PSer60 | phosphorylation up-regulates → | COPS6 | 23095642 | SIGNOR-252532 |
| AKT1 | phosphorylation up-regulates → | KHSRP PSer193 | phosphorylation down-regulates ⊣ | KHSRP | 17177604 | SIGNOR-252497 |
| AKT1 | phosphorylation up-regulates → | VIM PSer39 | phosphorylation up-regulates → | VIM | 20856200 | SIGNOR-252511 |
| AKT1 | phosphorylation up-regulates → | PFKFB2 PSer483 | phosphorylation up-regulates → | PFKFB2 | 12853467 | SIGNOR-252464 |
| AKT1 | phosphorylation up-regulates → | TENT2 PSer116 | phosphorylation down-regulates ⊣ | TENT2 | 31057087 | SIGNOR-259405 |
| AKT1 | phosphorylation up-regulates → | VCP PSer748 | phosphorylation up-regulates → | VCP | 16551632 | SIGNOR-252493 |
| AKT1 | phosphorylation up-regulates → | BTK PSer51 | phosphorylation down-regulates ⊣ | BTK | 23754751 | SIGNOR-276466 |
| AKT1 | phosphorylation up-regulates → | YWHAZ PSer58 | phosphorylation down-regulates ⊣ | YWHAZ | 11956222 | SIGNOR-116587 |
| AKT1 | phosphorylation up-regulates → | HNRNPA1 PSer199 | phosphorylation down-regulates ⊣ | HNRNPA1 | 18562319 | SIGNOR-252519 |
| AKT1 | phosphorylation up-regulates → | HSPB1 PSer82 | phosphorylation down-regulates ⊣ | HSPB1 | 19593530 | SIGNOR-252526 |
| AKT1 | phosphorylation up-regulates → | ATXN1 PSer775 | phosphorylation up-regulates → | ATXN1 | 12757707 | SIGNOR-252561 |
| AKT1 | phosphorylation up-regulates → | PDCD4 PSer457 | phosphorylation down-regulates ⊣ | PDCD4 | 16357133 | SIGNOR-252488 |
| AKT1 | phosphorylation up-regulates → | TP53RK PSer250 | phosphorylation up-regulates → | TP53RK | 17712528 | SIGNOR-252503 |
| AKT1 | phosphorylation up-regulates → | STK3 PThr117 | phosphorylation down-regulates ⊣ | STK3 | 20231902 | SIGNOR-252509 |
| AKT1 | phosphorylation up-regulates → | ACAP1 PSer554 | phosphorylation down-regulates ⊣ | ACAP1 | 16256741 | SIGNOR-252483 |
| AKT1 | phosphorylation up-regulates → | BRAF PSer365 | phosphorylation down-regulates ⊣ | BRAF | 10869359 | SIGNOR-251471 |
| AKT1 | phosphorylation up-regulates → | TBC1D4 PThr642 | phosphorylation down-regulates ⊣ | TBC1D4 | 16880201 | SIGNOR-252494 |
| AKT1 | phosphorylation up-regulates → | MVD PSer96 | phosphorylation up-regulates → | MVD | 25378391 | SIGNOR-265891 |
| AKT1 | phosphorylation up-regulates → | AKT1S1 PThr246 | phosphorylation down-regulates ⊣ | AKT1S1 | 12524439 | SIGNOR-252544 |
| AKT1 | phosphorylation up-regulates → | TKT PThr382 | phosphorylation up-regulates → | TKT | 24981175 | SIGNOR-265101 |
| AKT1 | phosphorylation up-regulates → | KDM5A PThr1225 | phosphorylation up-regulates → | KDM5A | 27292631 | SIGNOR-274063 |
| AKT1 | phosphorylation up-regulates → | FOXO PSer197 | phosphorylation down-regulates ⊣ | FOXO | 10217147 | SIGNOR-252861 |
| AKT1 | phosphorylation up-regulates → | CARD11 PSer652 | phosphorylation up-regulates → | CARD11 | 24548923 | SIGNOR-276620 |
| AKT1 | phosphorylation up-regulates → | SH2B2 PSer598 | phosphorylation down-regulates ⊣ | SH2B2 | 16141217 | SIGNOR-252577 |
| AKT1 | phosphorylation up-regulates → | TARBP2 PSer286 | phosphorylation up-regulates → | TARBP2 | 27407113 | SIGNOR-274067 |
| AKT1 | phosphorylation up-regulates → | ESR1 PSer104 | phosphorylation up-regulates → | ESR1 | 11108261 | SIGNOR-84963 |
| AKT1 | phosphorylation up-regulates → | MASTL PThr299 | phosphorylation up-regulates → | MASTL | 32123010 | SIGNOR-277515 |
| AKT1 | phosphorylation up-regulates → | MAP2K4 PSer80 | phosphorylation down-regulates ⊣ | MAP2K4 | 11707464 | SIGNOR-236494 |
| AKT1 | phosphorylation up-regulates → | LTB4R2 PThr324 | phosphorylation down-regulates ⊣ | LTB4R2 | 22044535 | SIGNOR-252516 |
| AKT1 | phosphorylation up-regulates → | PTK2 PSer695 | phosphorylation up-regulates → | PTK2 | 23264741 | SIGNOR-276437 |
| AKT1 | phosphorylation up-regulates → | GSK3B PSer9 | phosphorylation down-regulates ⊣ | GSK3B | 23552696 | SIGNOR-245416 |
| AKT1 | phosphorylation up-regulates → | FOXO3 PSer315 | phosphorylation down-regulates ⊣ | FOXO3 | 19951971 | SIGNOR-249627 |
| AKT1 | phosphorylation up-regulates → | NR3C1 PSer134 | phosphorylation down-regulates ⊣ | NR3C1 | 24291004 | SIGNOR-252543 |
| AKT1 | phosphorylation up-regulates → | CDKN1A PSer146 | phosphorylation up-regulates → | CDKN1A | 31575057 | SIGNOR-157790 |
| AKT1 | phosphorylation up-regulates → | CASP9 PSer196 | phosphorylation down-regulates ⊣ | CASP9 | 15004527 | SIGNOR-252472 |
| AKT1 | phosphorylation up-regulates → | ACLY PSer455 | phosphorylation down-regulates ⊣ | ACLY | 12107176 | SIGNOR-245255 |
| AKT1 | phosphorylation up-regulates → | MXD1 PSer145 | phosphorylation down-regulates ⊣ | MXD1 | 19526459 | SIGNOR-252525 |
| AKT1 | phosphorylation up-regulates → | CCT2 PSer260 | phosphorylation down-regulates ⊣ | CCT2 | 19332537 | SIGNOR-184922 |
| AKT1 | phosphorylation up-regulates → | NCOR1 PSer1450 | phosphorylation down-regulates ⊣ | NCOR1 | 23940660 | SIGNOR-198913 |
| AKT1 | phosphorylation up-regulates → | SKP2 PSer72 | phosphorylation down-regulates ⊣ | SKP2 | 19270695 | SIGNOR-278274 |
| AKT1 | phosphorylation up-regulates → | ITCH PSer257 | phosphorylation up-regulates → | ITCH | 30517763 | SIGNOR-272922 |
| AKT1 | phosphorylation up-regulates → | MITF PSer516 | phosphorylation down-regulates ⊣ | MITF | 27702651 | SIGNOR-277281 |
| AKT1 | phosphorylation up-regulates → | PDE3B PSer295 | phosphorylation up-regulates → | PDE3B | 10454575 | SIGNOR-252583 |
| AKT1 | phosphorylation up-regulates → | NUAK1 PSer600 | phosphorylation up-regulates → | NUAK1 | 12409306 | SIGNOR-252591 |
| AKT1 | phosphorylation up-regulates → | ZFP36L1 PSer92 | phosphorylation down-regulates ⊣ | ZFP36L1 | 15538381 | SIGNOR-130376 |
| AKT1 | phosphorylation up-regulates → | NPM1 PSer48 | phosphorylation down-regulates ⊣ | NPM1 | 25071014 | SIGNOR-276667 |
| AKT1 | phosphorylation up-regulates → | NR4A1 PSer351 | phosphorylation down-regulates ⊣ | NR4A1 | 11274386 | SIGNOR-252466 |
| AKT1 | phosphorylation up-regulates → | YBX1 PSer102 | phosphorylation up-regulates → | YBX1 | 15806160 | SIGNOR-252475 |
| AKT1 | phosphorylation up-regulates → | NQO1 PSer40 | phosphorylation down-regulates ⊣ | NQO1 | 31358653 | SIGNOR-276868 |
| AKT1 | phosphorylation up-regulates → | CYCS PTyr47 | phosphorylation down-regulates ⊣ | CYCS | 32781572 | SIGNOR-277237 |
| AKT1 | phosphorylation up-regulates → | FOXO PSer262 | phosphorylation down-regulates ⊣ | FOXO | 16272144 | SIGNOR-252854 |
| Regulator | Mechanism/Effect | Target | SIGNOR-ID |
|---|---|---|---|
| AKT1 | phosphorylation → up-regulates quantity by stabilization | ACOT4 | SIGNOR-271820 |
| AKT1 | phosphorylation down-regulates | METTL1 | SIGNOR-24994 |
| AKT1 | phosphorylation → up-regulates | YBX1 | SIGNOR-252521 |
| AKT1 | phosphorylation → up-regulates activity | CARD11 | SIGNOR-276256 |
| AKT1 | phosphorylation → down-regulates activity | RUNX2 | SIGNOR-280176 |
| AKT1 | phosphorylation → down-regulates activity | CASP9 | SIGNOR-252581 |
| AKT1 | phosphorylation → up-regulates | TERT | SIGNOR-67317 |
| AKT1 | phosphorylation → up-regulates | ESR1 | SIGNOR-84975 |
| AKT1 | phosphorylation → down-regulates activity | FOXO | SIGNOR-252841 |
| AKT1 | phosphorylation → down-regulates activity | TSC | SIGNOR-235340 |
| AKT1 | phosphorylation → up-regulates | EP300 | SIGNOR-148983 |
| AKT1 | phosphorylation → down-regulates activity | FOXO3 | SIGNOR-252524 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | FOXO | SIGNOR-252845 |
| AKT1 | phosphorylation down-regulates | FOXO | SIGNOR-252843 |
| AKT1 | phosphorylation → up-regulates | CTNNB1 | SIGNOR-252499 |
| AKT1 | phosphorylation → up-regulates activity | BLVRA | SIGNOR-275517 |
| AKT1 | phosphorylation → unknown | RANBP3 | SIGNOR-252504 |
| AKT1 | phosphorylation down-regulates | PHF20 | SIGNOR-252529 |
| AKT1 | phosphorylation → up-regulates activity | CELF1 | SIGNOR-280173 |
| AKT1 | phosphorylation → down-regulates activity | GAPDH | SIGNOR-280174 |
| AKT1 | phosphorylation → up-regulates activity | PRKCD | SIGNOR-280175 |
| AKT1 | phosphorylation → up-regulates activity | UPF1 | SIGNOR-277597 |
| AKT1 | phosphorylation → up-regulates activity | DOCK6 | SIGNOR-275666 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | FOXO | SIGNOR-252844 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | FBXO31 | SIGNOR-277376 |
| AKT1 | phosphorylation → down-regulates activity | SIRT6 | SIGNOR-278465 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | MDM2 | SIGNOR-116270 |
| AKT1 | phosphorylation → down-regulates activity | BAD | SIGNOR-252562 |
| AKT1 | phosphorylation → up-regulates | SRPK2 | SIGNOR-186760 |
| AKT1 | phosphorylation → down-regulates activity | CABLES1 | SIGNOR-276756 |
| AKT1 | phosphorylation → down-regulates activity | GSK3B | SIGNOR-252546 |
| AKT1 | phosphorylation → down-regulates activity | ADAR | SIGNOR-276193 |
| AKT1 | phosphorylation → down-regulates activity | FOXO | SIGNOR-252848 |
| AKT1 | phosphorylation down-regulates | PDCD4 | SIGNOR-252496 |
| AKT1 | phosphorylation → down-regulates activity | BAD | SIGNOR-252563 |
| AKT1 | phosphorylation → down-regulates activity | LARP1 | SIGNOR-260991 |
| AKT1 | phosphorylation down-regulates | CDKN1C | SIGNOR-252536 |
| AKT1 | phosphorylation → up-regulates activity | PTK2 | SIGNOR-279775 |
| AKT1 | phosphorylation → up-regulates activity | PTK2 | SIGNOR-279776 |
| AKT1 | phosphorylation → up-regulates activity | HSF1 | SIGNOR-278373 |
| AKT1 | phosphorylation → up-regulates activity | MDM2 | SIGNOR-116274 |
| AKT1 | phosphorylation down-regulates | MAP3K11 | SIGNOR-252592 |
| AKT1 | phosphorylation → up-regulates activity | SH2B2 | SIGNOR-252557 |
| AKT1 | phosphorylation → down-regulates activity | EZH2 | SIGNOR-141043 |
| AKT1 | phosphorylation → down-regulates activity | BECN1 | SIGNOR-279667 |
| AKT1 | phosphorylation → up-regulates activity | HSF1 | SIGNOR-277581 |
| AKT1 | phosphorylation → up-regulates activity | RARG | SIGNOR-277492 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | FOXO3 | SIGNOR-249626 |
| AKT1 | phosphorylation → up-regulates activity | HSF1 | SIGNOR-277578 |
| AKT1 | phosphorylation → up-regulates activity | MAPK1 | SIGNOR-279136 |
| AKT1 | phosphorylation → up-regulates activity | PDK1 | SIGNOR-277272 |
| AKT1 | phosphorylation down-regulates | ADRB2 | SIGNOR-252469 |
| AKT1 | phosphorylation → up-regulates activity | CREB1 | SIGNOR-252549 |
| AKT1 | phosphorylation → unknown | ARFIP2 | SIGNOR-252476 |
| AKT1 | phosphorylation → up-regulates | TWIST1 | SIGNOR-164884 |
| AKT1 | phosphorylation down-regulates | FOXO | SIGNOR-252859 |
| AKT1 | phosphorylation → up-regulates | NCF1 | SIGNOR-252587 |
| AKT1 | phosphorylation down-regulates | HTRA2 | SIGNOR-252500 |
| AKT1 | phosphorylation down-regulates | GSK3A | SIGNOR-252589 |
| AKT1 | phosphorylation down-regulates | CDCA7 | SIGNOR-252533 |
| AKT1 | phosphorylation down-regulates | YAP1 | SIGNOR-252593 |
| AKT1 | phosphorylation → unknown | PFKFB2 | SIGNOR-252575 |
| AKT1 | phosphorylation → unknown | PALLD | SIGNOR-252510 |
| AKT1 | phosphorylation → up-regulates | VCP | SIGNOR-252492 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | FOXO | SIGNOR-252858 |
| AKT1 | phosphorylation down-regulates | FOXO | SIGNOR-252857 |
| AKT1 | phosphorylation → up-regulates activity | HSF1 | SIGNOR-277579 |
| AKT1 | phosphorylation → up-regulates activity | TARBP2 | SIGNOR-274064 |
| AKT1 | phosphorylation → down-regulates activity | FOXO3 | SIGNOR-252522 |
| AKT1 | phosphorylation → down-regulates activity | RPS6KA3 | SIGNOR-277548 |
| AKT1 | phosphorylation → up-regulates activity | PEA15 | SIGNOR-102092 |
| AKT1 | phosphorylation → up-regulates activity | PFKFB2 | SIGNOR-252528 |
| AKT1 | phosphorylation → up-regulates activity | S1PR1 | SIGNOR-252467 |
| AKT1 | phosphorylation → up-regulates | MST1R | SIGNOR-252471 |
| AKT1 | phosphorylation down-regulates | FOXO6 | SIGNOR-252582 |
| AKT1 | phosphorylation → down-regulates activity | TSC2 | SIGNOR-235511 |
| AKT1 | phosphorylation → down-regulates quantity | CTBP1 | SIGNOR-278304 |
| AKT1 | phosphorylation down-regulates | STK4 | SIGNOR-252537 |
| AKT1 | phosphorylation → unknown | PFKFB2 | SIGNOR-252574 |
| AKT1 | phosphorylation → up-regulates activity | LONP1 | SIGNOR-265724 |
| AKT1 | phosphorylation → up-regulates activity | BMI1 | SIGNOR-252559 |
| AKT1 | phosphorylation down-regulates | STK4 | SIGNOR-252507 |
| AKT1 | phosphorylation → up-regulates | DLX5 | SIGNOR-195546 |
| AKT1 | phosphorylation → up-regulates | BRCA1 | SIGNOR-163472 |
| AKT1 | phosphorylation → down-regulates activity | FOXO3 | SIGNOR-252523 |
| AKT1 | phosphorylation → up-regulates activity | PDE3B | SIGNOR-252554 |
| AKT1 | phosphorylation → up-regulates | DNMT1 | SIGNOR-170530 |
| AKT1 | phosphorylation → up-regulates activity | CARD11 | SIGNOR-276254 |
| AKT1 | phosphorylation → up-regulates | ESR1 | SIGNOR-84971 |
| AKT1 | phosphorylation down-regulates | FOXO | SIGNOR-252856 |
| AKT1 | phosphorylation → down-regulates activity | PLN | SIGNOR-252578 |
| AKT1 | phosphorylation → up-regulates | CLK2 | SIGNOR-167336 |
| AKT1 | phosphorylation → down-regulates activity | FOXO | SIGNOR-252862 |
| AKT1 | phosphorylation → down-regulates activity | BCL2L11 | SIGNOR-252487 |
| AKT1 | phosphorylation → down-regulates activity | FOXO | SIGNOR-252850 |
| AKT1 | phosphorylation → up-regulates activity | TMIGD2 | SIGNOR-273481 |
| AKT1 | phosphorylation → up-regulates activity | HSF1 | SIGNOR-278371 |
| AKT1 | phosphorylation → up-regulates | GATA1 | SIGNOR-139782 |
| AKT1 | phosphorylation → up-regulates | ESR1 | SIGNOR-84967 |
| AKT1 | phosphorylation → up-regulates activity | MAPKAP1 | SIGNOR-276932 |
| AKT1 | phosphorylation down-regulates | SKI | SIGNOR-252527 |
| AKT1 | phosphorylation → unknown | NIBAN1 | SIGNOR-252530 |
| AKT1 | phosphorylation → up-regulates activity | KDM5A | SIGNOR-274061 |
| AKT1 | phosphorylation → down-regulates activity | MAP3K5 | SIGNOR-252465 |
| AKT1 | phosphorylation → up-regulates activity | Hexokinase | SIGNOR-270267 |
| AKT1 | phosphorylation down-regulates | TAL1 | SIGNOR-252479 |
| AKT1 | phosphorylation → up-regulates activity | MAP3K8 | SIGNOR-252572 |
| AKT1 | phosphorylation → down-regulates activity | AR | SIGNOR-108508 |
| AKT1 | phosphorylation → up-regulates | WNK1 | SIGNOR-252481 |
| AKT1 | phosphorylation → up-regulates activity | PARK7 | SIGNOR-275582 |
| AKT1 | phosphorylation → up-regulates activity | PTK2 | SIGNOR-279777 |
| AKT1 | phosphorylation → up-regulates activity | SMURF1 | SIGNOR-279778 |
| AKT1 | phosphorylation → up-regulates activity | EPHA2 | SIGNOR-279787 |
| AKT1 | phosphorylation → down-regulates activity | FOXO1 | SIGNOR-236159 |
| AKT1 | phosphorylation → up-regulates activity | RAB3IP | SIGNOR-277802 |
| AKT1 | phosphorylation → up-regulates activity | LARP6 | SIGNOR-277213 |
| AKT1 | phosphorylation → down-regulates quantity | CFLAR | SIGNOR-252548 |
| AKT1 | phosphorylation → down-regulates activity | ADARB1 | SIGNOR-276194 |
| AKT1 | phosphorylation → up-regulates | CLK2 | SIGNOR-167340 |
| AKT1 | phosphorylation → down-regulates quantity | RNF11 | SIGNOR-252558 |
| AKT1 | phosphorylation down-regulates | RAF1 | SIGNOR-147963 |
| AKT1 | phosphorylation down-regulates | FOXO | SIGNOR-252853 |
| AKT1 | phosphorylation → up-regulates activity | PTK2 | SIGNOR-279774 |
| AKT1 | phosphorylation → up-regulates quantity | PFKP | SIGNOR-279788 |
| AKT1 | phosphorylation → up-regulates | PFKFB3 | SIGNOR-252477 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | FOXO | SIGNOR-252846 |
| AKT1 | phosphorylation → down-regulates activity | PAWR | SIGNOR-279668 |
| AKT1 | phosphorylation down-regulates | SH3RF1 | SIGNOR-252501 |
| AKT1 | phosphorylation → unknown | FANCA | SIGNOR-252567 |
| AKT1 | phosphorylation → up-regulates activity | AKT1 | SIGNOR-276054 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | MDM4 | SIGNOR-252517 |
| AKT1 | phosphorylation → up-regulates | ALYREF | SIGNOR-252518 |
| AKT1 | phosphorylation down-regulates | STK3 | SIGNOR-163537 |
| AKT1 | phosphorylation down-regulates | FOXO | SIGNOR-252847 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | FOXO3 | SIGNOR-249625 |
| AKT1 | phosphorylation → up-regulates activity | CBY1 | SIGNOR-279002 |
| AKT1 | phosphorylation → down-regulates activity | CABLES1 | SIGNOR-276757 |
| AKT1 | phosphorylation → up-regulates activity | USP14 | SIGNOR-265056 |
| AKT1 | phosphorylation → up-regulates | PIKFYVE | SIGNOR-252474 |
| AKT1 | phosphorylation → down-regulates activity | H3-3A | SIGNOR-98285 |
| AKT1 | phosphorylation down-regulates | GATA2 | SIGNOR-135614 |
| AKT1 | phosphorylation down-regulates | FOXO4 | SIGNOR-175291 |
| AKT1 | phosphorylation down-regulates | CHEK1 | SIGNOR-124365 |
| AKT1 | phosphorylation → down-regulates activity | FOXO4 | SIGNOR-252569 |
| AKT1 | phosphorylation down-regulates | FOXO4 | SIGNOR-252515 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | SOX2 | SIGNOR-279003 |
| AKT1 | phosphorylation down-regulates | FOXO4 | SIGNOR-252486 |
| AKT1 | phosphorylation → up-regulates | TERT | SIGNOR-67313 |
| AKT1 | phosphorylation down-regulates | ADRB2 | SIGNOR-252470 |
| AKT1 | phosphorylation → up-regulates activity | HK2 | SIGNOR-259984 |
| AKT1 | phosphorylation → down-regulates activity | ITGB3 | SIGNOR-252552 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | POU5F1 | SIGNOR-252545 |
| AKT1 | phosphorylation → up-regulates activity | ZRANB1 | SIGNOR-273484 |
| AKT1 | phosphorylation → up-regulates activity | IMPDH2 | SIGNOR-261262 |
| AKT1 | phosphorylation → down-regulates activity | TSC | SIGNOR-235628 |
| AKT1 | phosphorylation → up-regulates activity | MAP3K8 | SIGNOR-252571 |
| AKT1 | phosphorylation → up-regulates activity | AKT1 | SIGNOR-276055 |
| AKT1 | phosphorylation → up-regulates | VCP | SIGNOR-252491 |
| AKT1 | phosphorylation down-regulates | CDKN1B | SIGNOR-88294 |
| AKT1 | phosphorylation → up-regulates | CHUK | SIGNOR-187006 |
| AKT1 | phosphorylation down-regulates | CDKN1B | SIGNOR-121944 |
| AKT1 | phosphorylation → up-regulates activity | CARD11 | SIGNOR-276255 |
| AKT1 | phosphorylation down-regulates | FOXO1 | SIGNOR-105459 |
| AKT1 | phosphorylation down-regulates | PDCD4 | SIGNOR-252505 |
| AKT1 | phosphorylation → down-regulates activity | TSC2 | SIGNOR-235515 |
| AKT1 | phosphorylation → unknown | CARHSP1 | SIGNOR-252478 |
| AKT1 | phosphorylation down-regulates | RAF1 | SIGNOR-252588 |
| AKT1 | phosphorylation down-regulates | STK3 | SIGNOR-163533 |
| AKT1 | phosphorylation down-regulates | CDKN1C | SIGNOR-252535 |
| AKT1 | phosphorylation → down-regulates activity | CASP9 | SIGNOR-252585 |
| AKT1 | phosphorylation → up-regulates | TTC3 | SIGNOR-252508 |
| AKT1 | phosphorylation → up-regulates activity | PIK3R6 | SIGNOR-275722 |
| AKT1 | phosphorylation → down-regulates activity | BRAF | SIGNOR-251472 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | XIAP | SIGNOR-119488 |
| AKT1 | phosphorylation → up-regulates activity | KDM5A | SIGNOR-274060 |
| AKT1 | phosphorylation down-regulates | ZYX | SIGNOR-156122 |
| AKT1 | phosphorylation → up-regulates activity | PTK2 | SIGNOR-276436 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | BTK | SIGNOR-276465 |
| AKT1 | phosphorylation → up-regulates activity | LONP1 | SIGNOR-265725 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | USP4 | SIGNOR-273482 |
| AKT1 | phosphorylation down-regulates | TBC1D4 | SIGNOR-252594 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | BCL3 | SIGNOR-277358 |
| AKT1 | phosphorylation → down-regulates activity | LARP1 | SIGNOR-260992 |
| AKT1 | phosphorylation → down-regulates activity | FOXO4 | SIGNOR-252568 |
| AKT1 | phosphorylation → down-regulates activity | RAC1 | SIGNOR-252576 |
| AKT1 | phosphorylation → unknown | HMOX1 | SIGNOR-252506 |
| AKT1 | phosphorylation → up-regulates | NOS3 | SIGNOR-112363 |
| AKT1 | phosphorylation → up-regulates | DLX5 | SIGNOR-252513 |
| AKT1 | phosphorylation → up-regulates activity | HSF1 | SIGNOR-278372 |
| AKT1 | phosphorylation → down-regulates activity | BAX | SIGNOR-252538 |
| AKT1 | phosphorylation → up-regulates activity | ATG4B | SIGNOR-275834 |
| AKT1 | phosphorylation → up-regulates activity | RPS3 | SIGNOR-259815 |
| AKT1 | phosphorylation down-regulates | STK3/4 | SIGNOR-269945 |
| AKT1 | phosphorylation → up-regulates | SP7 | SIGNOR-252514 |
| AKT1 | phosphorylation → down-regulates activity | FOXO1 | SIGNOR-236206 |
| AKT1 | phosphorylation → down-regulates activity | FOXO1 | SIGNOR-236163 |
| AKT1 | phosphorylation → up-regulates | MDM2 | SIGNOR-124953 |
| AKT1 | phosphorylation → up-regulates | BRCA1 | SIGNOR-154312 |
| AKT1 | phosphorylation → up-regulates activity | HSF1 | SIGNOR-278374 |
| AKT1 | phosphorylation → up-regulates activity | NOS3 | SIGNOR-251622 |
| AKT1 | phosphorylation → up-regulates activity | PFKFB2 | SIGNOR-252584 |
| AKT1 | phosphorylation down-regulates | FOXO6 | SIGNOR-175294 |
| AKT1 | phosphorylation → down-regulates activity | PRKAA1 | SIGNOR-252739 |
| AKT1 | phosphorylation → unknown | HTT | SIGNOR-252590 |
| AKT1 | phosphorylation → up-regulates activity | CARD11 | SIGNOR-276621 |
| AKT1 | phosphorylation down-regulates | RARA | SIGNOR-252489 |
| AKT1 | phosphorylation → down-regulates activity | BECN1 | SIGNOR-279666 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | UBE2S | SIGNOR-265078 |
| AKT1 | phosphorylation → up-regulates activity | ZRANB1 | SIGNOR-273483 |
| AKT1 | phosphorylation → up-regulates activity | HSF1 | SIGNOR-277580 |
| AKT1 | phosphorylation → up-regulates | AGAP2 | SIGNOR-183543 |
| AKT1 | phosphorylation down-regulates | FOXO4 | SIGNOR-252484 |
| AKT1 | phosphorylation down-regulates | FOXO | SIGNOR-252860 |
| AKT1 | phosphorylation down-regulates | AR | SIGNOR-154631 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | SOX2 | SIGNOR-277445 |
| AKT1 | phosphorylation → unknown | Histone H3 | SIGNOR-265320 |
| AKT1 | phosphorylation → down-regulates activity | FOXO | SIGNOR-252849 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | NQO1 | SIGNOR-276869 |
| AKT1 | phosphorylation → down-regulates activity | BAD | SIGNOR-52863 |
| AKT1 | phosphorylation → down-regulates quantity | SYTL1 | SIGNOR-273540 |
| AKT1 | phosphorylation → down-regulates activity | DAB2IP | SIGNOR-254780 |
| AKT1 | phosphorylation → up-regulates activity | FBXW7 | SIGNOR-276328 |
| AKT1 | phosphorylation → up-regulates | NCF1 | SIGNOR-252586 |
| AKT1 | phosphorylation → unknown | CCDC88A | SIGNOR-252482 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | MDM2 | SIGNOR-124949 |
| AKT1 | phosphorylation → down-regulates activity | AR | SIGNOR-108504 |
| AKT1 | phosphorylation → down-regulates activity | FOXO | SIGNOR-252851 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | CDKN1A | SIGNOR-149698 |
| AKT1 | phosphorylation → unknown | DLC1 | SIGNOR-252550 |
| AKT1 | phosphorylation → up-regulates activity | KDM5A | SIGNOR-274062 |
| AKT1 | phosphorylation → down-regulates activity | IRAK1 | SIGNOR-252551 |
| AKT1 | phosphorylation → up-regulates activity | ILF3 | SIGNOR-252512 |
| AKT1 | phosphorylation down-regulates | FOXO | SIGNOR-252855 |
| AKT1 | phosphorylation → down-regulates activity | PTPN1 | SIGNOR-252542 |
| AKT1 | phosphorylation → up-regulates | CDK2 | SIGNOR-178058 |
| AKT1 | phosphorylation → unknown | MTOR | SIGNOR-251099 |
| AKT1 | phosphorylation down-regulates | GAB2 | SIGNOR-252468 |
| AKT1 | phosphorylation down-regulates | FOXO4 | SIGNOR-252485 |
| AKT1 | phosphorylation → up-regulates | IKK-complex | SIGNOR-217460 |
| AKT1 | phosphorylation → down-regulates activity | BAD | SIGNOR-52859 |
| AKT1 | phosphorylation → up-regulates activity | PDE3B | SIGNOR-252573 |
| AKT1 | phosphorylation → down-regulates activity | PRKAA1 | SIGNOR-276461 |
| AKT1 | phosphorylation → up-regulates activity | mTORC1 | SIGNOR-252539 |
| AKT1 | phosphorylation → up-regulates activity | HIRA | SIGNOR-279584 |
| AKT1 | phosphorylation → up-regulates activity | RAB3IP | SIGNOR-277816 |
| AKT1 | phosphorylation → up-regulates activity | TIFA | SIGNOR-273542 |
| AKT1 | phosphorylation → up-regulates activity | KDM5A | SIGNOR-274059 |
| AKT1 | phosphorylation → down-regulates activity | PPARGC1A | SIGNOR-252502 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | NHEJ1 | SIGNOR-276881 |
| AKT1 | phosphorylation → up-regulates | EP300 | SIGNOR-158624 |
| AKT1 | phosphorylation → up-regulates | EIF4B | SIGNOR-252520 |
| AKT1 | phosphorylation down-regulates | CDKN1B | SIGNOR-179109 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | FOXO1 | SIGNOR-209647 |
| AKT1 | phosphorylation → up-regulates activity | SCYL1 | SIGNOR-265496 |
| AKT1 | phosphorylation → up-regulates activity | PFKFB2 | SIGNOR-252555 |
| AKT1 | phosphorylation → up-regulates | COPS6 | SIGNOR-252532 |
| AKT1 | phosphorylation → down-regulates activity | KHSRP | SIGNOR-252497 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | VIM | SIGNOR-252511 |
| AKT1 | phosphorylation → up-regulates activity | PFKFB2 | SIGNOR-252464 |
| AKT1 | phosphorylation down-regulates | RAF1 | SIGNOR-252531 |
| AKT1 | phosphorylation → down-regulates activity | TENT2 | SIGNOR-259405 |
| AKT1 | phosphorylation → up-regulates | VCP | SIGNOR-252493 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | BTK | SIGNOR-276466 |
| AKT1 | phosphorylation → unknown | YWHAZ | SIGNOR-116587 |
| AKT1 | phosphorylation down-regulates | HNRNPA1 | SIGNOR-252519 |
| AKT1 | phosphorylation down-regulates | HSPB1 | SIGNOR-252526 |
| AKT1 | phosphorylation → up-regulates | P300/PCAF | SIGNOR-217670 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | ATXN1 | SIGNOR-252561 |
| AKT1 | phosphorylation down-regulates | PDCD4 | SIGNOR-252488 |
| AKT1 | phosphorylation → up-regulates | TP53RK | SIGNOR-252503 |
| AKT1 | phosphorylation down-regulates | STK3 | SIGNOR-252509 |
| AKT1 | phosphorylation → unknown | ACAP1 | SIGNOR-252483 |
| AKT1 | phosphorylation → down-regulates activity | BRAF | SIGNOR-251471 |
| AKT1 | phosphorylation → unknown | TBC1D4 | SIGNOR-252494 |
| AKT1 | phosphorylation → up-regulates activity | MVD | SIGNOR-265891 |
| AKT1 | phosphorylation → down-regulates activity | AKT1S1 | SIGNOR-252544 |
| AKT1 | phosphorylation → up-regulates activity | TKT | SIGNOR-265101 |
| AKT1 | phosphorylation → up-regulates activity | KDM5A | SIGNOR-274063 |
| AKT1 | phosphorylation → down-regulates activity | FOXO | SIGNOR-252861 |
| AKT1 | phosphorylation → up-regulates activity | CARD11 | SIGNOR-276620 |
| AKT1 | phosphorylation → unknown | SH2B2 | SIGNOR-252577 |
| AKT1 | phosphorylation → up-regulates activity | TARBP2 | SIGNOR-274067 |
| AKT1 | phosphorylation → up-regulates activity | mTORC1 | SIGNOR-252540 |
| AKT1 | phosphorylation → up-regulates | ESR1 | SIGNOR-84963 |
| AKT1 | phosphorylation → down-regulates activity | FOXO3 | SIGNOR-175288 |
| AKT1 | phosphorylation → up-regulates activity | MASTL | SIGNOR-277515 |
| AKT1 | phosphorylation down-regulates | MAP2K4 | SIGNOR-236494 |
| AKT1 | phosphorylation → up-regulates | SP7 | SIGNOR-195549 |
| AKT1 | phosphorylation down-regulates | FOXO1 | SIGNOR-175285 |
| AKT1 | phosphorylation → unknown | LTB4R2 | SIGNOR-252516 |
| AKT1 | phosphorylation → up-regulates activity | PTK2 | SIGNOR-276437 |
| AKT1 | phosphorylation → down-regulates activity | GSK3B | SIGNOR-245416 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | FOXO3 | SIGNOR-249627 |
| AKT1 | phosphorylation down-regulates | NR3C1 | SIGNOR-252543 |
| AKT1 | phosphorylation → up-regulates quantity by stabilization | CDKN1A | SIGNOR-157790 |
| AKT1 | phosphorylation down-regulates | CASP9 | SIGNOR-252472 |
| AKT1 | phosphorylation → unknown | ACLY | SIGNOR-245255 |
| AKT1 | phosphorylation down-regulates | MXD1 | SIGNOR-252525 |
| AKT1 | phosphorylation → unknown | CCT2 | SIGNOR-184922 |
| AKT1 | phosphorylation down-regulates | NCOR1 | SIGNOR-198913 |
| AKT1 | phosphorylation → down-regulates activity | SKP2 | SIGNOR-278274 |
| AKT1 | phosphorylation → up-regulates quantity | ITCH | SIGNOR-272922 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | MITF | SIGNOR-277281 |
| AKT1 | phosphorylation → up-regulates | PDE3B | SIGNOR-252583 |
| AKT1 | phosphorylation → up-regulates | NUAK1 | SIGNOR-252591 |
| AKT1 | phosphorylation down-regulates | ZFP36L1 | SIGNOR-130376 |
| AKT1 | phosphorylation → down-regulates activity | NPM1 | SIGNOR-276667 |
| AKT1 | phosphorylation → down-regulates activity | NR4A1 | SIGNOR-252466 |
| AKT1 | phosphorylation → up-regulates | YBX1 | SIGNOR-252475 |
| AKT1 | phosphorylation down-regulates quantity by destabilization | NQO1 | SIGNOR-276868 |
| AKT1 | phosphorylation → down-regulates activity | CYCS | SIGNOR-277237 |
| AKT1 | phosphorylation → up-regulates | mTORC1 | SIGNOR-255844 |
| AKT1 | phosphorylation down-regulates | FOXO | SIGNOR-252854 |
| AKT1 | phosphorylation → up-regulates | MTOR | SIGNOR-255107 |