Entity Details

Name AKT1_Ser477
ID P31749
Role residue
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Data Summary
PTM Format
SIGNOR Summary
Modifier Substrate Residue Sequence Mechanism/Effect PMID Interaction ID
mTORC2AKT1Ser477
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PQFSYSAsGTAphosphorylation
up-regulates activity		24670654SIGNOR-252441
CyclinA2/CDK2AKT1Ser477
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PQFSYSAsGTAphosphorylation
up-regulates activity		24670654SIGNOR-252440
Enzyme Effect Phosphosite Effect Target PMID Interaction ID
mTORC2phosphorylation
up-regulates
→
AKT1
PSer477		phosphorylation
up-regulates
→		AKT124670654SIGNOR-252441
CyclinA2/CDK2phosphorylation
up-regulates
→
AKT1
PSer477		phosphorylation
up-regulates
→		AKT124670654SIGNOR-252440
Regulator Mechanism/Effect Target SIGNOR-ID
mTORC2phosphorylation
→
up-regulates activity 		AKT1SIGNOR-252441
CyclinA2/CDK2phosphorylation
→
up-regulates activity 		AKT1SIGNOR-252440